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Objective— To analyze the effect of the intraoperative use of sodium carboxymethylcellulose (CBMC) and related perioperative factors on postoperative colic and survival in horses that had abdominal surgery for colic.
Study Design— Retrospective study.
Animals— Horses (n=203) that had surgery for small intestinal disease; 33 horses had intraoperative administration of CBMC.
Methods— Information was obtained from medical records for 170 horses that had surgery for colic before use of CBMC and 33 horses that had intraoperative CBMC. Kaplan–Meier survival curves were used to estimate median survival time and a Cox proportional hazards model was used to estimate the hazard ratio for the effect of CBMC and other perioperative variables on survival.
Results— Seventy-five percent of horses administered CBMC survived to 180 days, whereas 75% of untreated horses survived 8 days (median survival time=18 days). Horses not administered CBMC were twice as likely to die compared with horses administered CBMC. Horses that had postoperative ileus (POI) were 1.4 times more likely to die than horses without ileus. Similarly, horses with signs of colic after surgery were 1.3 times more likely to die than horses without postoperative signs of colic.
Conclusions— CBMC administration is seemingly protective against death and prolongs survival when used intraoperatively in horses with small intestine disease, particularly horses with postoperative colic or POI. Both POI and colic increased risk of death after surgery.
Clinical Relevance— Intraoperative administration of CBMC in horses that have surgery for small intestinal disease may improve survival, possibly by reducing early adhesion formation.  相似文献   
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The problems are as numerous and diverse as the biology of the various organisms causing damage to crops. They are compounded by the differences in reaction of crops cultivated in different ways, by weather sequences over long periods or short periods and the interactions of all three factors;noxious organisms, crops and weather. To ensure that control measures are economically justified, their need must be assessed on the basis of probable crop loss if no precautions are taken. The relationship between the intensity and timing of the infestation of the crop by the noxious organisms, crop damage and crop loss must be determined. In some instances, this is straight forward;in others, very complicated. The assessment of the probability of infestation may be based on existing population levels, on intervening weather, on crop examination for the start of infestation, on the occurrence of critical environmental conditions, or on the transport of inoculum. Having developed a warning system, how is the information conveyed to the grower? Warning systems are based on past experience, but how stable are they ? Pathogens change, crop cultivation practices change, available controls change. The problems of estimating the need for and timing or control measures are likely to be continuing ones for the biologist and crop specialist. Les problèmes sont aussi nombreux et diversifyés que la biologie des organismes nuisibles eux-mêmes. Les réactions dissemblables des cultures soumises à différents modes de culture, les séquences méteorologiques à court et a long terme ainsi que les interactions entre L'organisme nuisible, la culture et le temps sont autant d'élements qui ajoutent à la complexite des phénomenes. La justification économique dune méthode de lutte repose sur I'évaluation de la perte de récolte a laquelle il faut s'attendre en I'absence de protection. Cette évaluation, plus ou moins diffcile, tiendra compte de I'importance et de la durée de la contamination en fonction du dommage que subit la culture et des pertes de récoltes qui en résultent. L'évaluation de la probabilityé d'une infestation peut reposer sur la densité de la population au moment du contrble, les conditions météorologiques prévalentes, la detection d'une attaque primaire de la culture, L'apparition de conditions critiques dans une biocoenose, ou la possibilityé de dissemination de L'inoculum. Lorsqu'un système d'avertissement a éte développé, la question est de savoir de quelle faGon L'information peut atteindre le cultivateur. Les systemés d'avertissement sont basés sur des expériences acquises, mais quelle est leur fiabilite ? L'organisme change de méme que les modes de culture et de lutte. I1 s'ensuit que I'evaluation de la necessite et du moment de I'intervention phytosanitaire doit être continuellement reconsideré par le biologiste et I'agronome.  相似文献   
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Objectives— To compare short‐ and long‐term functional and radiographic outcome of cranial cruciate ligament (CrCL) injury in dogs treated with postoperative physical rehabilitation and either tibial plateau leveling osteotomy (TPLO) or lateral fabellar suture stabilization (LFS). Study Design— Prospective observational clinical study. Animals— Medium to large breed dogs with naturally occurring CrCL injury (n=65). Methods— Dogs with CrCL injury were treated with either TPLO or LFS and with identical physical rehabilitation regimes postoperatively. Limb peak vertical force (PVF) was measured preoperatively and at 3, 5, and 7 weeks, and 6 months and 24 months postoperatively. Stifles were radiographically assessed for osteoarthrosis (OA) preoperatively and 24 months postoperatively. Results— Thirty‐five dogs had LFS and 30 dogs had TPLO. Radiographic OA scores were significantly increased at 24 months compared with preoperative scores in all dogs. Radiographic OA scores preoperatively and at 24 months were not significantly different between treatment groups. PVF was significantly increased from preoperative to 24 months among both treatment groups but not significantly different between treatment groups preoperatively or at 3, 5, 7 weeks, 6, or 24 months. Conclusion— No significant difference in outcome as determined by ground reaction forces or radiographic OA scores were found between dogs with CrCL injury treated with LFS or TPLO. Clinical Relevance— LFS and TPLO remain good options for stabilizing stifles with CrCL injury with all dogs showing significant functional improvement. This study does not support the superiority of either surgical technique.  相似文献   
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JOSH REXING  DVM    DIANNE DUNNING  DVM  MS  Diplomate ACVS    ARTHUR M. SIEGEL  DVM  PhD    KIM KNAP  BS  CVT  CCRP    BOBBIE WERBE  RVT 《Veterinary surgery : VS》2010,39(1):54-58
Objective— To compare 4 therapeutic techniques to reduce soft tissue swelling after cranial cruciate ligament repair in the dog.
Study Design— Prospective study.
Animals— Twenty-four dogs with cranial cruciate ligament rupture (CCLR).
Methods— Dogs with naturally occurring CCLR, were surgically repaired by an extracapsular technique and randomly divided into 4 treatment groups (cold compression [CC], modified Robert Jones bandage [B], cold compression and bandage [CCB], and microcurrent electrical therapy and bandage [METB]) each with 6 dogs. Data were collected at 2 time points, the morning after surgery before the 1st treatment and 72 hours later after the last treatment. Limb girth was measured at 3 anatomic locations to assess soft tissue swelling and all affected limbs were evaluated for presence (or absence) of pitting edema and bruising. Analysis of covariance was used to determine effect of treatment on the percent change in circumference. Duncan's multiple-range test was used to determine differences in treatment groups circumferential percent change over 72 hours. Statistical significance was set at P <.05.
Results— Use of a Robert Jones bandage had the least effect on reducing postoperative soft tissue swelling with CC, METB, and CCB being equally effective in reducing swelling by 72 hours after surgery.
Conclusion— Use of cold compresses alone or with a bandage, or using microcurrent electrical therapy in combination with a bandage decreases soft tissue swelling over 72 hours more than a bandaging alone after extracapsular repair of CCLR.
Clinical Relevance— CC, METB, and CCB should be considered as viable options to limit soft tissue swelling after extracapsular repair of CCLR in dogs.  相似文献   
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