The spleen morphophysiology of fruit bats     

Desrayni Hanadhita  Anisa Rahma  Andhika Yudha Prawira  Ni Luh Putu Ika Mayasari  Aryani Sismin Satyaningtijas  Eiichi Hondo  Srihadi Agungpriyono 《Anatomia, histologia, embryologia》2019,48(4):315-324

Spleen is one of the important lymphoid organs with wide variations of morphological and physiological functions according to species. Morphology and function of the spleen in bats, which are hosts to several viral strains without exhibiting clinical symptoms, remain to be fully elucidated. This study aims to examine the spleen morphology of fruit bats associated with their physiological functions. Spleen histological observations were performed in three fruit bats species: Cynopterus titthaecheilus (n = 9), Rousettus leschenaultii (n = 3) and Pteropus vampyrus (n = 3). The spleens of these fruit bats were surrounded by a thin capsule. Red pulp consisted of splenic cord and wide vascular space filled with blood. Ellipsoids in all three studied species were found numerously and adjacent to one another forming macrophages aggregates. White pulp consisted of periarteriolar lymphoid sheaths (PALS), lymphoid follicles and marginal zone. The lymphoid follicle contained a germinal centre and a tingible body macrophage that might reflect an active immune system. The marginal zone was prominent and well developed. This study reports some differences in spleen structure of fruit bats compared to other bat species previously reported and discusses possible physiological implications of the spleen based on its morphology.  相似文献   

Radiographic anatomy of the heart of fruit bats     

Anisa Rahma  Desrayni Hanadhita  Andhika Yudha Prawira  Dwi Utari Rahmiati  Gunanti Gunanti  Hera Maheshwari  Aryani Sismin Satyaningtijas  Srihadi Agungpriyono 《Anatomia, histologia, embryologia》2021,50(3):604-613

As the only mammal that can fly, bats have organ systems with a unique morphophysiology. One of the highlights is the heart and blood circulation system, which must be able to meet the needs of blood and oxygen supply when flying. This study examined the radiography of the normal condition of the heart organ in 3 species of fruit bats, namely Cynopterus titthaecheilus, Cynopterus brachyotis and Rousettus leschenaultii using radiological silhouette analysis and clock analogy. The results showed that the heart positions of the three bat species tend to be tilted to the left with the apex moving away from the midsagittal plane. Analysis of intercostal space (ICS) value and vertebral heart score (VHS), and evaluation of radiographic features showed R. leschenaultii has a relatively larger heart size than the other two species. All three bat species have a higher VHS than mammals in general. Radiographic images obtained, and interpretation results show the position, size and normal heart parts of the three bat species. They will be useful in diagnostic efforts related to heart problems in these three species.  相似文献   

Extracellular matrix composition of different spleen compartments of fruit bats     

Desrayni Hanadhita  Anisa Rahma  Muhammad R. Wahid  Ni Luh Putu I. Mayasari  Aryani S. Satyaningtijas  Eiichi Hondo  Srihadi Agungpriyono 《Anatomia, histologia, embryologia》2020,49(2):281-289

The distribution and composition of extracellular matrix (ECM) of the spleen in two species of fruit bats, namely Cynopterus titthaecheilus and Rousettus leschenaultii, were examined by histochemistry and immunohistochemistry. Reticular fibres accompanied by laminin were identified to make up the splenic stromal network. Types I and III collagen were identified in various spleen compartments with varying intensities. Thin and short elastin fibres were scattered in several parts of the spleen. Visualization of the ECM of the spleen can better demonstrate spleen compartmentalization. The alleged vascular space structure in the fruit bats spleen was the sinus structure that was strengthened by the presence of reticular fibres that limit the sinus basement membrane. The present study identified periellipsoidal lymphoid sheath (PELS)-like structure in fruit bats spleen that had never been identified in mammals before. In addition to describing the structure, this study highlighted the variations in ECM composition of the spleen between species that can provide new insight into the phylogenetic study of spleen morphology.  相似文献