Ovine hereditary chondrodysplasia (spider syndrome) in Suffolk lambs   总被引：1，自引：0，他引：1  

PH PHILLIPS  CM BUNN  CE ANDERSON 《Australian veterinary journal》1993,70(2):73-74

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Minimum duration of effective head-only electrical stunning of fallow deer (Dama dama) and time to loss of consciousness following a throat-cut     

Cook CJ  Gilbert KV  Devine CE  Dean JM  Hogg B 《New Zealand veterinary journal》1994,42(4):156-157

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Immunohistochemical differentiation of reactive from malignant mesothelium as a diagnostic aid in canine pericardial disease          下载免费PDF全文

E. Milne  Y. Martinez Pereira  C. Muir  T. Scase  D. J. Shaw  G. McGregor  L. Oldroyd  E. Scurrell  M. Martin  C. Devine  H. Hodgkiss‐Geere 《The Journal of small animal practice》2018,59(5):261-271

Objectives

To develop a provisional immunohistochemistry panel for distinguishing reactive pericardium, atypical mesothelial proliferation and mesothelioma in dogs.

Materials and Methods

Archived pericardial biopsies were subject to haematoxylin and eosin staining, immunohistochemistry for cytokeratin, vimentin, insulin‐like growth factor II mRNA‐binding protein 3, glucose transporter 1 and desmin. Samples were scored for intensity and number of cells stained.

Results

Ten biopsies of reactive mesothelium, 17 of atypical mesothelial proliferation, 26 of mesothelioma and five of normal pericardium were identified on the basis of haematoxylin and eosin staining. Cytokeratin and vimentin were expressed in all biopsies, confirming mesothelial origin. Normal pericardial samples had the lowest scores for insulin‐like growth factor II mRNA‐binding protein 3, glucose transporter 1 and desmin. Mesothelioma and atypical proliferative samples were similar to each other, with higher scores for insulin‐like growth factor II mRNA‐binding protein 3 and glucose transporter 1 than the reactive samples. Desmin staining was variable. Insulin‐like growth factor II mRNA‐binding protein 3 was the best to distinguish between disease groups.

Clinical Significance

An immunohistochemistry panel of cytokeratin, vimentin, insulin‐like growth factor II mRNA‐binding protein 3 and glucose transporter 1 could provide superior information compared with haematoxylin and eosin staining alone in the diagnosis of cases of mesothelial proliferation in canine pericardium, but further validation is warranted.  相似文献   

Inhibition of acetolactate synthase in susceptible and resistant biotypes of Stellaria media     

Malcolm D. Devine  M. A. Susan Maries  Linda M. Hall 《Pest management science》1991,31(3):273-280

Acetolactate synthase (ALS) from one susceptible and two chlorsulfuronresistant biotypes of Stellaria media(L.) Vill. was assayed in the presence of eight known ALS inhibitors. As expected, ALS from the chlorsulfuronresistant biotypes (R1 and R2) showed reduced sensitivity to chlorsulfuron and other sulfonylurea herbicides. The patterns of cross-resistance varied, however, indicating that the alteration in ALS that confers chlorsulfuron resistance does not confer the same level of resistance to other sulfonylurea herbicides. The resistant biotypes were highly cross-resistant to sulfometuron-methyl and DPX-A7H81, but less cross-resistant to triasulfuron. Both R1 and R2 were highly cross-resistant to DTPS (N-[2,6-dichlorophenyl]-5,7-dimethyl-1,2,4-iriazolo[1,5a]pyrimidine-2-siilfoiiamide), but only slightly cross-resistant to imazamethahenz, an imidazolinone herbicide. The differences in the patterns of cross-resistance observed presumably reflect differences in the binding affinity of the herbicides for the altered ALS. The data presented suggest, but do not confirm, that R1 and R2 contain the same ALS mutation.  相似文献   

New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UK     

Gorman K  Hewitt F  Denholm I  Devine GJ 《Pest management science》2002,58(2):123-130

A recent survey of insecticide resistance in two of the most problematic pests in UK glasshouses revealed some new developments. At least some individuals in all UK samples of Trialeurodes vaporariorum that were tested resisted the insect growth regulator (IGR) buprofezin. The most strongly resistant strains were unaffected by the field application rate of this compound, and even samples from populations that had never been exposed to buprofezin contained individuals that survived the highest concentration applied (10,000 mg litre-1). The field rate of buprofezin was shown to select for resistance through vapour action alone. The benzophenylurea teflubenzuron, an unrelated IGR, was cross-resisted by buprofezin-resistant individuals. There was no evidence of resistance to imidacloprid, but all T vaporariorum strains tested, regardless of origin, exhibited a high innate tolerance to nicotine, when compared with another whitefly species, Bemisia tabaci. Marked resistance to fenbutatin oxide and tebufenpyrad was found in single glasshouse populations of Tetranychus urticae, but these compounds and abamectin appeared to remain highly effective against all other strains collected.  相似文献   

Report of resistance to the neonicotinoid insecticide imidacloprid in Trialeurodes vaporariorum (Hemiptera: Aleyrodidae)   总被引：1，自引：0，他引：1  

Gorman K  Devine G  Bennison J  Coussons P  Punchard N  Denholm I 《Pest management science》2007,63(6):555-558

Susceptibilities of UK and mainland European samples of Trialeurodes vaporariorum (Westwood) to the neonicotinoid insecticide imidacloprid were investigated over a 7 year period. All 24 strains collected between 1997 and 2003 showed similar baseline levels of susceptibility to that of a known susceptible laboratory strain when exposed to a diagnostic concentration (128 mg L(-1)) of formulated imidacloprid. Two samples collected during 2004, one from the UK and one from The Netherlands, demonstrated reduced susceptibility at this concentration. Using dose-response assays, the presence of resistant individuals was disclosed in both these strains; some individuals were unaffected at doses high enough to induce phytotoxic effects. This report represents the first confirmed cases of neonicotinoid resistance inducing control failures in T. vaporariorum, and highlights a need for careful vigilance to sustain the effectiveness of imidacloprid and related neonicotinoid insecticides.  相似文献   

关于内蒙古大兴安岭林区大径材培育的探讨     

策日格  刘科 《内蒙古林业调查设计》2011,34(1):58-59,65

文章通过对内蒙古大兴安岭林区培育大径材的目的、意义、必要性及方法等方面的分析,论述了大径级材培育是促进林区生态、经济和社会协调发展的有力措施。  相似文献   

Isotopic fractionation of stratospheric nitrous oxide     

YL Yung  CE Miller 《Science (New York, N.Y.)》1997,278(5344):1778-1780

We propose an isotopic fractionation mechanism, based on photolytic destruction, to explain the 15N/14N and 18O/16O fractionation of stratospheric nitrous oxide (N2O) and reconcile laboratory experiments with atmospheric observations. The theory predicts that (i) the isotopomers 15N14N16O and 14N15N16O have very different isotopic fractionations in the stratosphere, and (ii) laboratory photolysis experiments conducted at 205 nanometers should better simulate the observed isotopic fractionation of stratospheric N2O. Modeling results indicate that there is no compelling reason to invoke a significant chemical source of N2O in the middle atmosphere and that individual N2O isotopomers might be useful tracers of stratospheric air parcel motion.  相似文献   

Identification of a DNA nonhomologous end-joining complex in bacteria     

Weller GR  Kysela B  Roy R  Tonkin LM  Scanlan E  Della M  Devine SK  Day JP  Wilkinson A  d'Adda di Fagagna F  Devine KM  Bowater RP  Jeggo PA  Jackson SP  Doherty AJ 《Science (New York, N.Y.)》2002,297(5587):1686-1689

In eukaryotic cells, double-strand breaks (DSBs) in DNA are generally repaired by the pathway of homologous recombination or by DNA nonhomologous end joining (NHEJ). Both pathways have been highly conserved throughout eukaryotic evolution, but no equivalent NHEJ system has been identified in prokaryotes. The NHEJ pathway requires a DNA end-binding component called Ku. We have identified bacterial Ku homologs and show that these proteins retain the biochemical characteristics of the eukaryotic Ku heterodimer. Furthermore, we show that bacterial Ku specifically recruits DNA ligase to DNA ends and stimulates DNA ligation. Loss of these proteins leads to hypersensitivity to ionizing radiation in Bacillus subtilis. These data provide evidence that many bacteria possess a DNA DSB repair apparatus that shares many features with the NHEJ system of eukarya and suggest that this DNA repair pathway arose before the prokaryotic and eukaryotic lineages diverged.  相似文献   

Effect of Water Stress on the Yield of Cowpea (Vigna unguiculata L. Walp.) Genotypes in the Delmarva Region of the United States     

R. B. Dadson  F. M. Hashem  I. Javaid  J. Joshi  A. L. Allen  T. E. Devine 《Journal of Agronomy and Crop Science》2005,191(3):210-217

Drought is an important yield-reducing factor for corn and soya bean which are the two major crops in the Delaware, Maryland and Virginia (Delmarva) region of the United States. Cowpea (Vigna unguiculata L. Walp.) is primarily grown in drier regions of the world where it is one of the most drought-resistant food legumes. Field experiments were conducted in which 10 genetically diverse cowpea genotypes were evaluated for adaptability to the Delmarva area. The cowpea genotypes were grown in rain-out shelters under non-water-stressed and water-stressed conditions. The results showed that under non-water-stressed conditions cowpea genotypes California Blackeye 5, Champion and Mississippi Silver gave higher seed yields, while genotypes White Acre, Six Week Browneye and Texas Cream 8 provided lower seed yields. Genotypes California Blackeye 5 and Champion gave comparatively better seed yields under water-stressed conditions. California Blackeye 5 was the highest seed-yielding genotype under both water-stressed and non-water-stressed conditions. The highest biological yield under non-water-stressed conditions was given by genotypes Two Crop Brown, White Acre and Elite, whereas under the water-stressed condition genotypes Texas Cream 8, California Blackeye 5, and Mississippi Silver gave higher biological yield. Genotypes Quickpick Pinkeye and Elite were identified as early maturing genotypes. The harvest index (HI) varied significantly among genotypes, with Texas Cream 8 having the lowest HI. Cowpea genotypes which gave higher seed yield under water-stressed conditions could play an important role in sustaining crop production in the Delmarva region.  相似文献