Surgical repair of skull fractures in four horses using cuttable bone plates.     

B A Dowling  A J Dart  G Trope 《Australian veterinary journal》2001,79(5):324-327

Three horses with severely comminuted, open facial bone fractures and one horse with a comminuted, open orbital rim fracture were referred for treatment. Severe facial bone asymmetry and epistaxis were apparent in all cases and subcutaneous emphysema was present in two, however physical and neurological examinations were otherwise normal. Radiography and endoscopy were of some use in assessing the degree of damage, although the true extent of the damage was more apparent at surgery. Surgical reduction of the fractures was recommended to maximise cosmetic and functional outcome. After surgical debridement and reduction of the fractures the bone fragments remained unstable and were not amenable to stabilisation with interfragmentary wires alone, so 2 mm cuttable bone plates were used to maintain fracture alignment. Screw migration occurred in three horses and in one of these horses the plate had to be removed. Other complications were minor and in all horses the fractures healed with good cosmetic and functional outcome. The use of cuttable bone plates should be considered as a reasonable alternative to inter-fragmentary wiring for unstable, comminuted fractures of the facial bones, even where fractures are open.  相似文献   

Isotypic antibody responses in cattle infected with Haemophilus somnus   总被引：4，自引：0，他引：4  

P R Widders  S C Dowling  R P Gogolewski  J W Smith  L B Corbeil 《Research in veterinary science》1989,46(2):212-217

Bovine antibody responses to Haemophilus somnus were compared on the basis of clinical and bacteriological findings. Serum IgG1 and IgM antibody titres were significantly increased in clinically normal cattle that were bacteriologically positive for H somnus from the nasal or vaginal mucosae compared with clinically normal, negative cows. IgG2 titres did not differ significantly between these two groups. However, IgG2 antibody was significantly higher in animals with H somnus disease (pneumonia or abortion) than in clinically normal cattle (whether bacteriologically positive or negative), while IgG1 and IgM titres did not differ between diseased and bacteriologically positive, clinically normal cattle. These antibody trends were duplicated in experimental H somnus abortion or pneumonia, with the greatest response occurring within the IgG2 subclass. Cattle vaccinated systemically with killed whole H somnus produced a predominant IgG2 response with minimal IgG1 and IgM responses. These results demonstrate that IgG2 antibody is consistently elevated in H somnus disease, and suggest that this response may be useful in discriminating diseased from asymptomatic cattle.  相似文献   

Characterisation of faecal microbiota in horses medicated with oral doxycycline hyclate     

Ronan J. J. Chapuis  Anne A. M. J. Becker  Patricia M. Dowling  J. Scott Weese 《Equine veterinary journal》2023,55(1):129-141

  相似文献   

Cutaneous phycomycosis in two horses     

Dowling BA  Dart AJ  Kessell AE  Pascoe RR  Hodgson DR 《Australian veterinary journal》1999,77(12):780-783

  相似文献   

Update on therapy of canine epilepsy          下载免费PDF全文

Dowling PM 《The Canadian veterinary journal. La revue veterinaire canadienne》1999,40(8):595-598

  相似文献   

Catheters: a review of the selection, utilisation and complications of catheters for peripheral venous access     

Tan RH  Dart AJ  Dowling BA 《Australian veterinary journal》2003,81(3):136-139

Intravenous catheters are used for the administration of medications and fluids and are an integral part of veterinary practice. The aim of catheter use is to optimise administration of medication and minimise complications such as thrombus formation, thrombophlebitis and sepsis. Catheters made from teflon are less flexible, less durable and stimulate more tissue reaction than polyurethane or silicon. However silicon catheters are more expensive and complicated to insert. Generally, for veterinary practice, the biostability and cost of polyurethane catheters make them preferable for short and long-term use. The smallest diameter catheter should be selected to minimise internal vessel wall contact and irritation without compromising medication delivery. The site of insertion varies with individual preference, vessel access and patient compliance. The jugular, cephalic, saphenous, ear, lateral thoracic and subcutaneous abdominal veins are accessible. Hair removal and a thorough aseptic skin preparation should be performed prior to catheter insertion. Daily maintenance is required to detect complications and maximise catheter longevity. Potential complications include thrombus formation, thromboembolism, bacterial colonisation and septicaemia, blood loss and air embolism. Permanent or transient skin dwelling bacteria are commonly isolated if sepsis occurs. The development of novel antiseptic and antibiotic impregnated catheters may reduce the complications associated with catheter infection in the future.  相似文献   

Recombinant equine growth hormone administration: effects on synovial fluid biomarkers and cartilage metabolism in horses     

Dart AJ  Little CB  Hughes CE  Chu O  Dowling BA  Hodgson DR  Rose RJ  Johnson KA 《Equine veterinary journal》2003,35(3):302-307

REASONS FOR PERFORMING STUDY: Recombinant equine growth hormone (reGH) has recently been evaluated for effects on body condition and wound healing. It has the potential to influence articular cartilage via stimulation of IGF-1. OBJECTIVES: To investigate effects of administration on synovial joint metabolism. METHODS: Six mature horses were given 20 microg/kg bwt reGH daily for 8 weeks by i.m. injection. Three control horses were injected with sterile water. Serum and synovial fluid samples were collected at 6, 8, 11 and 16 weeks for GH and IGF-1 assays. Articular cartilage harvested at week 16 was evaluated by Western analysis using monoclonal antibodies BC-13, BC-4, 8-A-4 and CH-3. RESULTS: Concentrations of IGF-1 in serum and synovial fluid were significantly elevated (P < 0.05) at 6 and 8 weeks in the reGH group. Glycosaminoglycan concentrations in synovial fluid were significantly less than controls at these time points, suggesting that reGH may modulate proteoglycan metabolism in articular cartilage. In the reGH group, there were not any alterations in synovial fluid content of 3B3(-) epitope or aggrecan metabolite, or in aggrecan or link protein catabolites retained within cartilage, that might be expected with development of osteoarthritis. CONCLUSIONS: Intramuscular administration of reGH may be a more efficient means of delivery of IGF-1 to joints for cartilage resurfacing initiatives. POTENTIAL RELEVANCE: We found no alterations in cartilage metabolism indicative of development of osteoarthritis.  相似文献   

禽流感病毒抗原超滤浓缩重要参数的动态变化     

张彦杰  李爱芬 《中国兽药杂志》2007,41(10):16-17

采用世界先进的切向流超滤浓缩技术，对禽流感病毒（H9N2亚型）超滤浓缩成倍体积，测定血凝价HA和半数感染量EID50。结果HA成倍增加，废液HA呈阴性，病毒回收率达100％；受宿主鸡胚系统的影响，EID50与病毒量之间不是简单的直线关系，但病毒的活性不受影响。结果表明，所用超滤系统适用于禽流感病毒抗原的浓缩。  相似文献   

Oxytetracycline residues in tissue, organs, and eggs of poultry fed supplemented rations     

S E Katz  C A Fassbender  J J Dowling 《Journal of the Association of Official Analytical Chemists》1973,56(1):77-81

  相似文献   

Comments — incompassionate, and a negative contribution — A reply          下载免费PDF全文

Trisha Dowling  Ken Kilpatrick 《The Canadian veterinary journal. La revue veterinaire canadienne》2007,48(10):1001

  相似文献