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Small breed dogs (<15 kg) affected by cranial cruciate ligament rupture secondary to cranial cruciate ligament disease are usually middle-aged (mean age at presentation: 5.4 to 9.8 years); terrier breeds, miniature and toy poodles are over-represented. Small breed dogs have a different morphology of the proximal tibia compared to medium and large breed dogs with a steep tibial plateau angle (mean tibial plateau angle 28.8° to 36.3°), absent base of the flare of the tibial tuberosity and a caudally bowed fibula. There is a lack of evidence regarding the optimal management of cranial cruciate ligament rupture in small dogs. The treatment options consist of conservative management, extracapsular stabilisation, cranial closing wedge ostectomy, tibial plateau levelling osteotomy and tibial tuberosity advancement. The limited evidence available shows that conservative management is likely to result in prolonged recovery time (average time to recovery approximately 4 months). There is paucity of reports focussing on extracapsular stabilisation in small breed dogs, and questions have been raised regarding the early failure of the extracapsular suture subject to higher loads due to the steep tibial plateau angle of small breed dogs. Cranial closing wedge ostectomy and tibial plateau levelling osteotomy have been reported to have low major complication rates and good subjective outcomes. It is controversial whether tibial tuberosity advancement is a suitable technique in dogs with steep tibial plateau angle, which includes most small breed dogs.  相似文献   
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GI Gellene 《Science (New York, N.Y.)》1996,274(5291):1344-1346
Application of a theory of nuclear symmetry-based reaction restrictions to the O2 + O --> O3 reaction provides a potential explanation for the symmetry-induced isotopic enrichment observed for laboratory and atmospherically produced O3. Within this theory, the rate of formation of O3 from collisions of O and isotopically homonuclear O2 depends on whether the O2 molecule is in an f (allowed) or an e (restricted) parity label state. The restriction can be relaxed by various potential energy surface coupling terms, and the assumption that approximately 78 percent of the restricted O2(e) levels produce O3 with the same efficiency as the allowed O2(f) levels can account for laboratory-observed isotopic fractionation. In particular, the theory explains the special enhanced formation of the completely asymmetric isotopomer 16O17O18O.  相似文献   
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OBJECTIVE: To review surgical techniques and postoperative complications associated with correction of patellar luxation in dogs. STUDY DESIGN: Retrospective study. ANIMALS: Dogs (n = 109) with patellar luxation (n = 131). METHODS: Medical records of dogs that had corrective surgery for patellar luxation were reviewed. Signalment, history, grade and direction of patellar luxation, operative technique and clinical outcomes were retrieved. RESULTS: Overall frequency of postoperative complications was 18%. Frequency of major (requiring revision surgery) complications was 13%. Frequency of patellar reluxation was 8%. Frequency of overall, major, and patellar reluxation complications was higher for dogs weighing > or =20 kg compared with those <20 kg. Frequency of overall and major complications was higher for dogs with higher grades of patellar luxation. Femoral trochlear sulcoplasty resulted in lower frequency of patellar reluxation. Tibial tuberosity transposition (TTT) resulted in lower frequency of major complications and patellar reluxation. Retinacular/capsular release resulted in higher frequency of major complications. Patient age, gender, medial versus lateral patellar luxation, left versus right hindlimb, capsular/retinacular imbrication, use of anti-rotational sutures, and whether stifle surgery had been performed previously did not significantly influence frequency of complications. CONCLUSION: TTT and femoral trochlear sulcoplasty minimize the risk of postoperative patellar reluxation and major complications. CLINICAL RELEVANCE: Information derived from this study can be used to estimate the likelihood of postoperative complications for canine patients undergoing corrective surgery for patellar luxation.  相似文献   
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A 7 yr old spayed female mastiff presented for examination of a left pelvic limb lameness of 3 mo duration. Six years previously, the dog had undergone tibial plateau leveling osteotomy (TPLO) surgery of the left pelvic limb for the treatment of cranial cruciate disease. On presentation, the dog had a painful and swollen proximal tibia. Following investigation, a diagnosis of osteosarcoma of the proximal left tibia at the site of the previous TPLO surgery was made. This is the first reported case of osteosarcoma following TPLO using an implant other than the Slocum plate.  相似文献   
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This retrospective study identified 32 cases of patellar luxation which occurred as a complication of surgical intervention for cranial cruciate ligament rupture (CCLR). The complication was recorded mostly in larger (>/=20 kg) dogs with the Labrador Retriever being the most common breed. The complication followed extra-capsular, intra-capsular and tibial plateau levelling surgery. The mean time from CCLR surgery to the diagnosis of patellar luxation was 14 weeks. The incidence of patellar luxation occurring as a complication of surgical intervention for CCLR was 0.18% of all CCLR corrective procedures. Corrective surgery for patellar luxation was successful in 79% of stifles. The patellar reluxation rate was significantly lower (p = 0.0007) when at least one corrective osteotomy (tibial tuberosity transposition, femoral trochlear sulcoplasty or tibial plateau levelling osteotomy with tibial axial re-alignment) was performed (35%), compared to when corrective osteotomy was not performed (100% patellar reluxation rate). When performing corrective surgery for patellar luxation following CCLR surgery, at least one corrective osteotomy should be performed in order to reduce the patellar reluxation rate. The correction of patellar luxation following surgery for CCLR is challenging and carries a significant rate of failure.  相似文献   
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