Hyperlipemia and Ketonuria in an Alpaca and a Llama     

David E. Anderson  Peter D. Constable  Kathleen E. Yvorchuk  Neil V. Anderson  Guy St-Jean  Linda Rock 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1994,8(3):207-211

An alpaca and a llama in late stages of gestation were evaluated for lethargy, anorexia, and recumbency. Both camelids had cloudy, white, turbid serum, elevated serum triglyceride (1564, 5658 mg/dL, respectively) and cholesterol (158, 297 mg/dL, respectively) concentrations, and ketonuria. Signs of fetal stress were evident ultrasonographically in the alpaca, and a live cria was delivered by Cesarean section performed under general anesthesia. The alpaca developed severe metabolic acidosis, hepatic lipidosis, and acute renal failure secondary to renal lipidosis and died 36 hours after admission despite medical therapy. Histopathology revealed renal and hepatic lipidosis and neutrophilic pancreatitis. The cria died 72 hours after birth. The llama responded to IV electrolyte, dextrose, and regular crystalline insulin therapy. The pregnancy was maintained, and the llama was discharged from the hospital 20 days after admission. Two months after discharge, the llama gave birth to a live, 5 kg cria. Findings of hypertriglyceridemia, hypercholesterolemia, elevated sorbitol dehydrogenase activity, metabolic acidosis, azotemia, and ketonuria occurred in these two camelids. Based on this report, camelids appear to be similar to both horses and cattle in their response to severe energy imbalances in late gestation.  相似文献   

Specificities of antinuclear antibodies detected in dogs with systemic lupus erythematosus   总被引：4，自引：0，他引：4  

O Costa  C Fournel  E Lotchouang  J C Monier  M Fontaine 《Veterinary immunology and immunopathology》1984,7(3-4):369-382

Five hundred and eighty dogs with at least one clinical sign compatible with a systemic lupus erythematosus (SLE) were entered in a prospective study aimed at evaluating the prevalence of antinuclear antibodies (ANAb). SLE was diagnosed in 38 of these dogs (group A) which fulfilled at least four American Rheumatism Association (ARA) criteria; of these, sixteen had ANAb titers greater than or equal to 4096. The 23 dogs which met three or two ARA criteria (group B) had an ANAb geometric mean titer (GMT) of 259. Dogs (group C) with only 1 criterium had an ANAb GMT of 75. Anti-ds-DNA Ab were present in 6 dogs from group A (16%), and 2 dogs from group B (9%). Anti-histone Ab were present among dogs from group A, B and C with frequencies of 81%, 67% and 26%, respectively. Among dogs from group A, the ANAb titers and the levels of anti-histone Ab correlated positively when individual sera were considered. Antibodies against the soluble nuclear antigen (SNA) were detected in 74%, 39% and 13% of the dogs from groups A, B and C, respectively. Antibodies initially described in human SLE also exist in SLE dogs. Anti-Sm Ab were found in 24% of dogs in group A. With anti-RNP Ab the frequency was still lower (10%). However, two other types of anti-SNA Ab against RNAse and trypsin-resistant antigens, not found in human "reference sera", were often detected. The first type (anti-type 1 Ab) was found in 26% and 9% of group A and group B, The first type (anti-type 1 Ab) was found in 26% and 9% of group A and group B, respectively; the second type (anti-type 2 Ab) is less frequent, and was found in 13% and 17% of group A and B, respectively. It appears that testing for anti-Sm, anti-type 1 and anti-histone Ab should be performed in order to improve the diagnosis of SLE in dogs.  相似文献   

Ollulanus tricuspis in domestic cats - prevalence and methods of post-mortem diagnosis     

Guy PA 《New Zealand veterinary journal》1984,32(6):81-84

Ollulanus tricuspus is a parasite of the stomach of domestic cats and other animals, with a worldwide distribution. It can sometimes cause severe gastritis. Fifty-five cat stomachs were examined for O.tricuspis using three techniques. O.tricuspis was found in seven stomachs (13%) from adult cats; the number of parasites recovered from individual cats ranged from 9 to 119 (mean 54). The prevalence was higher than that previously recorded in New Zealand. Repeated dilution and sedimentation of the stomach contents and mucosal washings was found to be the most reliable detection method, being positive in all of the detected infections. Pepsin/HCI digestion of the stomach mucosa detected only 71% and punch sampling of the mucosa only 29% of these infections. This contrasts with an overseas study indicating that, in heavily infected cats, these techniques are similar in sensitivity. No macroscopic lesions were seen in the stomachs of infected cats.  相似文献   

Fine needle aspiration biopsy of malignant tumors in dogs and cats: a report of 102 cases          下载免费PDF全文

Ménard M  Fontaine M  Morin M 《The Canadian veterinary journal. La revue veterinaire canadienne》1986,27(12):504-510

Fine needle aspiration biopsy is a fast and inexpensive technique well tolerated by animals. Its efficacy for the diagnosis of malignancy and determination of cellular origin was investigated for 97 malignant tumors and five benign lesions in 83 dogs and 19 cats. Histological examination of the lesions was performed in each case. Malignancy was detected by cytology in 69% of the malignant tumors. The cellular origin of the lesion was determined in 74% of the cases. Confirmation of malignancy and determination of cellular origin permitted an early diagnosis and prognosis. Since fine needle aspiration biopsy and cytology cannot definitely rule out malignancy, a surgical biopsy and histopathology should be done when malignancy is suspected clinically and not confirmed cytologically. Specimens of good quality, adequate collaboration between the cytologist and clinicians, and sufficient knowledge of pathology and cytology are basic requirements for obtaining good results with fine needle aspiration biopsy and cytology.  相似文献   

Blood coagulation parameters in clinically normal intensively farmed red deer (Cervus elaphus) and fallow deer (Dama dama)     

Sutherland RJ  Saunders BW  Guy LA 《New Zealand veterinary journal》1985,33(1-2):14-16

Reference ranges for five parameters of blood coagulation were established in clinically normal farmed fallow deer (Dama dama) and red deer (Cervus elaphus). Storage of plasma at -15 degrees C resulted in small increases in activated partial thromboplastin time (APTT) for both species, and in the one stage prothrombin time (OSPT) of fallow deer, between days 1 and 30. These times were then stable between days 30 and 60. The fibrinogen levels of fallow deer plasma showed a small apparent increase over 60 days. These storage artefacts were not of sufficient magnitude to preclude the use of such plasma for diagnostic purposes although they could limit its use in research. Levels of fibrin/fibrinogen degradation products (FDP) were not affected by storage at -15 degrees C. Rabbit brain thromboplastin appeared adequate for OSPT determination in both species. The activated clotting time (ACT) is recommended as a field test for screening the intrinsic and common pathways of blood coagulation in deer.  相似文献   

Perceptions and opinions of pet owners in the United Sates about surgery,pain management,and anesthesia in dogs and cats          下载免费PDF全文

Bradley T. Simon DVM  MSc  DACVAA  Elizabeth M. Scallan DVM  MBA  MS  CVA  CCRP  Dirsko J. F. Von Pfeil DVM  DACVS  DECVS  DACVSMR  Daniel T. Boruta DVM  DACVAA  Rick Wall DVM  DACVSMR  CCRP  Belle M. Nibblett DVM  MVSc  DACVIM  O Odette DVM  DACVAA  Guy Beauchamp PhD  Paulo V. Steagall DVM  MSc  PhD  DACVAA 《Veterinary surgery : VS》2018,47(2):277-284

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Treatment of contaminated radial fracture in Sprague-Dawley rats by application of a degradable polymer releasing gentamicin     

Yuval Ramot  Michal Steiner  Netanel Amouyal  Yossi Lavie  Guy Klaiman  Abraham J. Domb  Abraham Nyska  Tal Hagigit 《Journal of toxicologic pathology》2021,34(1):11

Fracture-related infections remain a leading cause of morbidity and mortality. We aimed to establish a simple contaminated radial osteotomy model to assess the efficacy of a biodegradable polymer poly(sebacic-co-ricinoleic acid) [p(SA-RA)] containing 20% w/w gentamicin. A unilateral transverse osteotomy was induced in Sprague-Dawley (SD) rats, followed by application of Staphylococcus aureus suspension over the fracture. After successfully establishing the contaminated open fracture model, we treated the rats either systemically (intraperitoneal cefuroxime), locally with p(SA-RA) containing gentamicin, or both. Control groups included non-contaminated group and contaminated groups that were either untreated or treated with the polymer alone. After 4 weeks, the bones were subjected to micro-CT scanning and microbiological and histopathology evaluations. Micro-CT analysis revealed similar changes in the group subjected to both local and systemic treatment as in the non-contaminated control group. Lack of detectable bacterial growth was noted in most animals of the group subjected to both local and systemic treatment, and all samples were negative for S. aureus. Histopathological evaluation revealed that all treatment modalities containing antibiotics were highly effective in reducing infection and promoting callus repair, resulting in early bone healing. While p(SA-RA) containing gentamicin treatment showed better results than cefuroxime, the combination of local and systemic treatment displayed the highest therapeutic potential in this model.  相似文献   

Reference intervals for plasma,urinary, and salivary concentrations of free metanephrines in dogs: Relevance to the diagnosis of pheochromocytoma     

Marit F. van den Berg  Hans S. Kooistra  Guy C. M. Grinwis  Sebastiaan A. van Nimwegen  Martijn van Faassen  Ido P. Kema  Erik Teske  Sara Galac 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(1):173-183

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Liposome encapsulation and EDTA formulation of dsRNA targeting essential genes increase oral RNAi‐caused mortality in the Neotropical stink bug Euschistus heros     

Nathaly L Castellanos  Guy Smagghe  Rohit Sharma  Eugênio E Oliveira  Olivier Christiaens 《Pest management science》2019,75(2):537-548

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Investigation of the sensitivity of Plasmopara viticola to amisulbrom and ametoctradin in French vineyards using bioassays and molecular tools     

Sverine Fontaine  Florent Remuson  Laëtitia Caddoux  Benoit Barrs 《Pest management science》2019,75(8):2115-2123

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