Avian malaria in African black-footed penguins     

M K Stoskopf  J Beier 《Journal of the American Veterinary Medical Association》1979,175(9):944-947

Ten captive-reared African black-footed penguins (Spheniscus demersus) from a large outdoor colony were monitored for avian malaria, using several diagnostic tests. One treatment regimen was evaluated. Thin smear blood evaluation enabled detection of seven parasitemias involving Plasmodium relictum and Plasmodium elongatum in the penguins. Leukocytosis (relative lymphocytosis) was characteristic of infected birds. Parasitemia was detected as early as 21 days prior to onset of clinical signs (depression, anorexia, regurgitation, pale mucous membranes, and respiratory distress). The single bird that died had clinical signs only a few hours prior to its death. Treatment consisted of 0.03 mg of primaquine phosphate base/kg body weight, administered orally once daily for 3 days. Oral chloroquine phosphate therapy, given simultaneously, was administered in an initial loading dose of 10 mg of chloroquine phosphate base/kg body weight, followed by doses of 5 mg/kg at 6, 18 and 24 hours after the initial chloroquine dose. This treatment regimen prevented mortality and cleared parasites from the blood. Recurrences of malaria occurred in two birds that had received this treatment.  相似文献   

An outbreak of enzootic bovine leukosis in upper Egypt: clinical,laboratory and molecular-epidemiological studies     

Zaghawa A  Beier D  Abd El-Rahim IH  Karim I  El-ballal S  Conraths FJ  Marquardt O 《Journal of veterinary medicine. B, Infectious diseases and veterinary public health》2002,49(3):123-129

In 1989, 220 Holstein Friesian cattle (212 heifers and eight bulls) were imported from Minnesota, USA, to form a closed dairy herd in Arab El-Aoumar, Assiut, Upper Egypt. In November 1996, some abnormal signs such as loss of weight, decreased milk yield, external lymphadenopathy and decreased appetite were observed on this farm. Serological screening by enzyme-linked immunosorbent assay revealed a seroprevalence of antibodies directed against bovine leukaemia virus (BLV) of 37.7% in cattle under 2 years old and of 72.8% in animals more than 2 years old. Diagnosis was confirmed by the detection of BLV proviral DNA using polymerase chain reaction with primers amplifying a fragment of the env gene. Out of 21 tested leucocyte fractions from individual animals, 15 were positive showing a BLV-specific amplicon of 444 base pairs. Analysis of the amplicons for restriction fragment length polymorphisms and DNA sequencing results allowed the isolates to be typed. Since this was the first recorded case of enzootic bovine leukosis in Upper Egypt, strict quarantine measures were adopted and all serologically positive animals in the herd were culled.  相似文献   

Superficial digital flexor tendonitis in Thoroughbred race horses: outcome following non-surgical treatment and superior check desmotomy     

KT GIBSON  HM BURBIDGE  DU PFEIFFER 《Australian veterinary journal》1997,75(9):631-635

Objective This study documents the results of non-surgical treatment and treatment by superior check desmotomy in Thoroughbred racehorses with superficial digital flexor (SDF) tendonitis. Design A prospective study was made of 124 thoroughbred racehorses with unilateral or bilateral SDF tendonitis. Procedure The flexor tendons were assessed by physical and ultrasonographic examination before treatment, and the lesions detected in affected tendons were characterised according to lesion type, length and cross-sectional area. Ninety three horses were managed non-surgically and 31 by superior check desmotomy. Recurrent or new injuries were defined as injuries affecting a previously injured superficial digital flexor tendon, the contralateral SDF tendon, or the suspensory ligament (interosseous muscle) in either forelimb. Results No statistically significant difference was found in ultrasonographic lesion severity between treatment groups. Horses managed by superior check desmotomy were 1.3 times more likely to complete five or more races than horses managed non-surgically (95% confidence limits 0.93–1.82). Horses treated surgically were 1.2 times more likely to develop recurrent or new injuries after returning to training than horses managed non-surgically (95% CL 0.95–1.55). Horses under-going superior check desmotomy were 5.5 times more likely to develop suspensory desmitis than horses treated non-surgically (95% CL 1.13–26.4). There was no difference in the time to recurrent or new injury between treatment groups. Conclusion There was no statistically significant difference between treatment groups in the proportions of horses able to complete five or more races after an episode of superficial digital flexor tendonitis. Superior check desmotomy did not appear to offer an advantage over non-surgical treatment in preventing recurrent or new injuries in Thoroughbred racehorses. Horses undergoing superior check desmotomy appeared to be at greater risk of developing suspensery ligament injuries than horses managed non-surgically.  相似文献   

Hauptprobleme der forstlichen Entomologie in Dänemark (mit besonderer Berücksichtigung der Verhältnisse seit 1923)     

B. Beier Petersen 《Journal of pest science》1959,32(8):113-117

Ohne Zusammenfassung  相似文献   

Effect of dietary lactose on cecal pH, bacteriostatic volatile fatty acids, and Salmonella typhimurium colonization of broiler chicks   总被引：4，自引：0，他引：4  

D E Corrier  A Hinton  R L Ziprin  R C Beier  J R DeLoach 《Avian diseases》1990,34(3):617-625

One-day-old broiler chicks were inoculated with volatile fatty acid producing cecal flora from adult chickens. The chicks were divided into four groups and provided 1) no lactose, 2) 2.5% lactose in water, 3) 5% lactose in feed, or 4) 10% lactose in feed, until 10 days of age. All groups were challenged at 3 days of age with 10(6) or 10(8) S. typhimurium. At 10 days, the number of Salmonella in the ceca of the chicks challenged with 10(6) Salmonella was significantly decreased (P less than 0.01) in the groups provided lactose as compared with the controls. A significant decrease (P less than 0.01) in Salmonella numbers occurred in the chicks challenged with 10(8) Salmonella and provided 10% lactose. Providing 2.5% lactose or 5% lactose failed to inhibit Salmonella growth in chicks challenged with 10(8) Salmonella. The pH of the ceca of the groups provided lactose decreased significantly (P less than 0.05) and was accompanied by significant increases (P less than 0.01) in the concentrations of bacteriostatic acetic and propionic acids. Results showed that providing dietary lactose to broiler chicks and inoculation with normal cecal flora decreased cecal pH, increased the concentrations of bacteriostatic volatile fatty acids, and inhibited Salmonella colonization.  相似文献   

Small isolated aspen stands enrich bird communities in southwestern ponderosa pine forests     

Kerry L. Griffis-Kyle  Paul Beier 《Biological conservation》2003,110(3):375-385

Small aspen stands are disappearing from the landscape in the Southwest, so it is important to understand their contribution to the avian community. We sampled birds in 53 small, isolated aspen stands and 53 paired plots within the ponderosa pine forest in northern Arizona, during the 1996 and 1997 breeding seasons. Bird species richness and abundance were higher in aspen than in pine. However, bird species richness and abundance did not vary with size of the aspen patch or isolation index. In addition, direct ordination of species distributions with habitat factors suggested no distinct avian communities. This suggests that aspen stands do not harbor separate populations, but rather are locations where the regional avifauna reaches high local density and richness and may be crucial to birds in years of resource scarcity. Thus it is important for avian conservation to maintain many aspen stands across the landscape, encompassing a diversity of vegetation structure and composition.  相似文献   

Sequence interpretation. Functional annotation of mouse genome sequences     

Nadeau JH  Balling R  Barsh G  Beier D  Brown SD  Bucan M  Camper S  Carlson G  Copeland N  Eppig J  Fletcher C  Frankel WN  Ganten D  Goldowitz D  Goodnow C  Guenet JL  Hicks G  Hrabe de Angelis M  Jackson I  Jacob HJ  Jenkins N  Johnson D  Justice M  Kay S  Kingsley D  Lehrach H  Magnuson T  Meisler M  Poustka A  Rinchik EM  Rossant J  Russell LB  Schimenti J  Shiroishi T  Skarnes WC  Soriano P  Stanford W  Takahashi JS  Wurst W  Zimmer A;International Mouse Mutagenesis Consortium 《Science (New York, N.Y.)》2001,291(5507):1251-1255

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Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications   总被引：12，自引：0，他引：12  

S L Hoffman  C N Oster  C V Plowe  G R Woollett  J C Beier  J D Chulay  R A Wirtz  M R Hollingdale  M Mugambi 《Science (New York, N.Y.)》1987,237(4815):639-642

The first human vaccines against the malaria parasite have been designed to elicit antibodies to the circumsporozoite protein of Plasmodium falciparum. However, it is not known whether any level of naturally acquired antibodies to the circumsporozoite protein can predict resistance to Plasmodium falciparum malaria. In this study, 83 adults in a malaria-endemic region of Kenya were tested for circumsporozoite antibodies and then treated for malaria. They were monitored for the development of new malaria infections for 98 days. Antibody levels, as determined by four assays in vitro, were indistinguishable between the 60 individuals who did and the 23 who did not develop parasitemia during follow-up, and there was no apparent relation between day of onset of parasitemia and level of antibodies to circumsporozoite protein. Unless immunization with sporozoite vaccines induces antibodies that are quantitatively or qualitatively superior to the circumsporozoite antibodies in these adults, it is unlikely that such antibodies will prevent infection in areas with as intense malaria transmission as western Kenya.  相似文献   

Aluminium sulphate solubility in acid forest soils in Denmark     

Per Gundersen  Claus Beier 《Water, air, and soil pollution》1988,39(3-4):247-261

Ion leaching in 3 sandy spruce forest soils of different origin and pH was investigated in the laboratory. Zero-tension lysimeters containing undisturbed soil columns of varying soil depth were subjected to H₂SO₄ loadings for a period of 9 weeks. The analysis of the resulting leachate supports the hypothesis that Al-sulphate minerals may form in acidic soils when exposed to acid (H₂SO₄) deposition. In the B horizon of a glaciofluvial sandy soil (pH 4.2), both H⁺ and sulphate ions were retained to maintain 2pH + PSO₄ = 11.9 in the leachate solutions. This relation between H⁺ and sulphate activity may be due to an adsorption mechanism or a precipitation mechanism. The precipitation mechanism is favored by the good fit of leachate composition to the conditions for jurbanite [AlOHSO₄] formation from gibbsite [Al(OH)₃]. In the B horizon of a sandy till at pH 3.7, the Al in soil solution (0.5 mmol L^?1) was leached with sulphate. As the sulphate load was increased, some sulphate was retained. This may also be due to the dissolution and precipitation of an Al-sulphate mineral. The ion activity products of leachate solutions from the B horizon of this soil were close to the pK_s reported for jurbanite. The conditions for the possible existence and/or formation of Al-sulphate minerals in acidic soils are discussed.  相似文献   

Modelling ”clean rain” treatments in acidified soils-EXMAN project results     

Charlotta Walse  Claus Beier  Per Warfvinge  Lennart Rasmussen 《Water, air, and soil pollution》1995,85(3):1807-1812

The SAFE dynamic model was applied to a ”clean rain” roof experiment performed within the EXMAN project. In the experiment ambient throughfall was removed and replaced with artificial ”clean throughfall”. Input of S, N and H to the forest ecosystem was reduced by 75–100%. The results of the modelling show, that the time scales of model predictions and experiments are the same. The change in base cation flux was well reproduced, while the simulation of changes in aluminum flux was less successful. pH stayed constant in the experiment as well as in the calculations.  相似文献