Gossypol toxicity in preruminant calves     

RZ ZELSKI  JT ROTHWELL†  RE MOORE‡  DJ KENNEDY§ 《Australian veterinary journal》1995,72(10):394-398

SUMMARY Twenty-four of 57 calves fed a diet containing 33% cotton seed meal (CSM) died between 7 and 15 weeks of age. Initial deaths were not accompanied by premonitory signs, but after CSM withdrawal most calves developed rough coats, anorexia, weakness, ascites and subcutaneous oedema. Those that died had large volumes of serous fluid in the body cavities, hard livers of ‘nutmeg’ appearance, and pulmonary congestion. Histopathologically the livers showed periacinar necrosis in acute cases and periacinar fibrosis in chronic cases. Lungs from several calves had oedema, haemosiderosis and fibrosis in some pulmonary vessels. Atrophy of myocardial fibres was present in most cases. The concentration of free gossypol in the diet was 100 to 220 mg/kg. Ante-mortem and post-mortem findings supported a diagnosis of gossypol poisoning. The deaths continued for 4 weeks after withdrawal of CSM from the diet.  相似文献   

Primary tonsillar mast cell tumour in a dog          下载免费PDF全文

CC Shekell  MJ Thomson  RI Miller  JT Mackie 《Australian veterinary journal》2018,96(5):184-187

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What is your neurologic diagnosis? Osteochondroma of the dorsal process of T4     

Marioni K  Hathcock JT  Simpson ST 《Journal of the American Veterinary Medical Association》2001,219(7):917-920

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Coccygeal muscle injury in English Pointers (limber tail)     

Steiss J  Braund K  Wright J  Lenz S  Hudson J  Brawner W  Hathcock J  Purohit R  Bell L  Horne R 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1999,13(6):540-548

A condition colloquially referred to as "limber tail" and "cold tail" is familiar to people working with hunting dogs, primarily Pointers and Labrador Retrievers. The typical case consists of an adult dog that suddenly develops a flaccid tail. The tail either hangs down from the tail base or is held out horizontally for several inches from the tail base and then hangs straight down or at some degree below horizontal. Initially, the hair on the dorsal aspect of the proximal tail may be raised and dogs may resent palpation of the area 3-4 inches (8-10 cm) from the tail base. Most dogs recover spontaneously within a few days to weeks. Anecdotal reports suggest that anti-inflammatory drugs administered within 24 hours after onset hasten recovery. Less than one half of affected dogs experience a recurrence. Affected Pointers almost always have a history of prolonged cage transport, a hard workout the previous day, or exposure to cold or wet weather Most owners and trainers familiar with the condition do not seek veterinary assistance. In cases where people are not familiar with this disease, other conditions such as a fracture, spinal cord disease, impacted anal glands, or prostatic disease have been incorrectly diagnosed. We examined 4 affected Pointers and found evidence of coccygeal muscle damage, which included mild elevation of creatine kinase early after onset of clinical signs, needle electromyographic examination showing abnormal spontaneous discharges restricted to the coccygeal muscles several days after onset, and histopathologic evidence of muscle fiber damage. Specific muscle groups, namely the laterally positioned intertransversarius ventralis caudalis muscles, were affected most severely. Abnormal findings on thermography and scintigraphy further supported the diagnosis.  相似文献   

Tissue-print hybridization using a non-radioactive probe for the detection of infectious bursal disease virus.     

T L Hathcock  J J Giambrone 《Avian diseases》1992,36(2):202-205

Tissue-print hybridization was evaluated as a simplified means for detection of infectious bursal disease virus (IBDV) in the bursa of Fabricius from infected chickens. The assay employed a biotin-labeled synthetic oligonucleotide as a probe. The bound probe was detected using a color assay consisting of streptavidin conjugated to alkaline phosphatase. Bursae were imprinted onto nitrocellulose and then hybridized with the biotinylated probe. Bursal prints from IBDV-infected chickens were readily distinguished from control prints by color development and differences in signal intensity.  相似文献   

LOW-FIELD MAGNETIC RESONANCE IMAGING OF EARLY SUBCHONDRAL CYST-LIKE LESIONS IN INDUCED CRANIAL CRUCIATE LIGAMENT DEFICIENT DOGS     

Debra K.  Baird  DVM  John T.  Hathcock  DVM  MS  Steven A.  Kincaid  DVM  MS  PhD  Paul F.  Rumph  DVM  MS  John  Kammermann  MS  William R.  Widmer  DVM  MS  Denise  Visco  PhD  Donald  Sweet  MD 《Veterinary radiology & ultrasound》1998,39(3):167-173

Six healthy adult male mongrel dogs underwent cranial cruciate ligament transection in the left stifle. Survey radiography of both stifles and low-field (0.064 T) MRI of the left stifle were performed preoperatively and at 2, 6, and 12 weeks postoperatively. Focal changes in signal intensity were seen with MRI in the subchondral bone of the medial tibial condyle at 2 and 6 weeks postoperatively. At 12 weeks postoperative, a cyst-like lesion was detected using MRI in the subchondral bone of the medial tibial condyle in 4 of 6 dogs and a less defined lesion at this site in the remaining 2 dogs. The cyst-like lesion was spherical in shape and showed typical characteristics of fluid with low signal intensity on T1-weighted images, high signal intensity on T2-weighted images and high signal intensity on inversion recovery images. The lesion was seen in the subchondral bone of the caudal medial and/or middle region of the tibial plateau slightly cranial to the insertion of the caudal cruciate ligament. No subchondral cysts were seen in the tibia on radiographs. Histopathologically, the tibia was characterized by a loose myxomatous phase of early subchondral cyst formation.  相似文献   

COMPUTED TOMOGRAPHY OF THE LLAMA HEAD: TECHNIQUE AND NORMAL ANATOMY     

John T.  Hathcock  DVM  MS  D. G. Pugh  DVM  MS  Robert E.  Cartee  DVM  MS  Linda  Hammond  DVM 《Veterinary radiology & ultrasound》1995,36(4):290-296

Computed tomography was performed on the head of 6 normal adult llamas. The animals were under general anesthesia and positioned in dorsal recumbency on the scanning table. The area scanned was from the external occipital protuberance to the rostral portion of the nasal passage, and the images are presented in both a bone window and a soft tissue window to allow evaluation and identification of the anatomy of the head. Computed tomography of the llama head can be accomplished by most computed tomography scanners utilizing a technique similar to that used in small animals with minor modification of the scanning table.  相似文献   

First case of psittacine proventricular dilatation syndrome (macaw wasting disease) in Australia     

ND SULLIVAN  JT MACKIE  RI MILLER  A. GILES 《Australian veterinary journal》1997,75(9):674-674

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Chlamydiosis in workers at a duck farm and processing plant   总被引：4，自引：0，他引：4  

DG HINTON  A. SHIPLEY†  JW GALVIN‡  JT HARKIN‡  RA BRUNTON† 《Australian veterinary journal》1993,70(5):174-176

SUMMARY An outbreak of chlamydiosis was Investigated in workers at a duck farm and processing plant during winter 1989. Chlamydia psittaci was isolated from ducks, but there was little evidence of clinical chlamydiosis in the ducks. Serological tests showed that 76% of workers had been exposed to Infection, 12% recently, 16% had not been exposed and 8% had inconclusive test results. There was a strong association (P < 0.05) between years of employment and exposure to Infection. Infection appeared to be contracted during the first year of employment. Measures were Implemented to reduce shed contamination and control rodents and wild birds. At the same time, ducks were medicated, the processing plant was modified, work practices were altered and workers were advised about chlamydiosis to reduce the risk of human infection.  相似文献   

Diagnosis of equine herpesvirus 1 abortion using polymerase chain reaction     

JT MACKIE  GA MACLEOD  GH REUBEL  MJ STUDDERT 《Australian veterinary journal》1996,74(5):390-391

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