Enzootic nasal tumor (ENT) is a contagious neoplasm associated with enzootic nasal tumor virus (ENTV), which may induce disease in sheep (ENTV-1) and goats (ENTV-2). This study aimed to describe the occurrence of ENT in two Texel sheep (Ovis aries) from a 75-sheep flock, located in the city of Gravataí, southern Brazil. Animals used to be purchased from different origins, and no specific tests for disease monitoring or quarantine procedure were performed. Affected animals presented respiratory distress, anorexia with severe weight loss, and mucopurulent unilateral nasal discharge. Necropsy was performed in both animals and nasal cavity masses were observed. Histopathological analysis demonstrated an epithelial neoplasm compatible with nasal adenocarcinoma. PCR using a protocol that amplifies a 591 bp sequence of 5’LTR-gag region of ENTV1 was performed followed by DNA sequencing. Both samples were positive, and the sequences obtained presented highest identity (97%) with ENTV strain TN28 (GenBank accession number MH899613) detected in a Texel sheep from Scotland. This is the first report of ENTV-1 leading to enzootic nasal tumor in sheep in Latin America, which confirms the presence of the retrovirus in sheep flocks in the Brazilian territory.
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Luan C. Henker Regina T. Kemper Simone P. Bianchi Marcele B. Bandinelli Saulo P. Pavarini 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2019,48(2):255-258
A 9‐year‐old mixed breed 13 kg spayed female dog was presented for evaluation of two masses in the right abdominal mammary gland region. Surgery was conducted to excise the masses. A grade I complex mammary gland carcinoma and high grade (grade III) mast cell tumor with an inguinal lymph node metastasis were diagnosed. Forty‐seven days after the surgical procedure, the mast cell tumor relapsed, and neoadjuvant treatment with lomustine (81 mg/m2) was prescribed. Thirteen days from initiation of lomustine therapy, the dog was re‐presented to the hospital with bloody diarrhea, hematemesis, epistaxis, an elevated rectal temperature, depression, severe dehydration, and marked dyspnea. The CBC showed severe thrombocytopenia and leukopenia. According to the owner, lomustine (45mg per os [PO]) was mistakenly administered daily for 10 consecutive days (total dose, 810 mg/m2). The dog died and a necropsy was performed. The main gross lesions consisted of severe multifocal hemorrhages in multiple organs, especially in the digestive system. Histopathologic evaluation revealed disseminated hemorrhages, as well as marked bone marrow aplasia. This report describes the clinical, hematologic, gross, and histologic findings in a fatal case of lomustine overdose in a dog. 相似文献
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de Cecco Bianca Santana Lorenzett Marina Paula Henker Luan Cleber Weber Matheus Nunes Moséna Ana Cristina Sbaraini Baumbach Letícia Canal Cláudio Wageck Driemeier David Pavarini Saulo Petinatti Sonne Luciana 《Tropical animal health and production》2019,51(7):2095-2098
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Ronaldo V. Leite‐Filho Welden Panziera Marcele B. Bandinelli Luan C. Henker Kalinka da Conceio Monteiro Luis G. Corbellini David Driemeier Luciana Sonne Saulo P. Pavarini 《Veterinary and comparative oncology》2020,18(2):224-230
A retrospective study compiling cases of feline lymphoma diagnosed during 12 years (2004‐2016) in Southern Brazil was performed. A total of 125 cases of lymphoma diagnosed in cats were reviewed, and information including age, breed, sex and tumour topography were collected. FeLV and FIV immunohistochemical tests were performed, as well as immunophenotyping of lymphomas. The alimentary form represented the most common presentation (42/125), followed by mediastinal lymphoma (35/125). Out of 125 cases, 79 presented positive retroviral immunostaining in tumour tissue (52 FeLV alone, 14 FIV alone and 13 presented FIV and FeLV co‐infections), 66/125 of the cases were of T‐cell origin and 59/125 of the cases were of B‐cell origin. The median age of cats with T‐cell lymphoma was 120 months (10‐240 months), and 60 months (6‐204 months) for cats with B‐cell lymphoma. The most frequent alimentary tumour presentation was the enteropathy‐associated T‐cell lymphoma (type 1), and the major type of mediastinal tumour observed was diffuse large B‐cell lymphoma. Considering only mediastinal and alimentary lymphomas (n = 77), the prevalence of mediastinal lymphoma in FeLV‐positive cats was 2.21 times higher than the prevalence of this type of tumour in FeLV‐negative cats (P = .036). Mediastinal lymphoma was more frequently observed in younger cats, and the prevalence of mediastinal tumours in these animals was 3.06 times higher than the prevalence of this tumour form in old cats (P = .0125). The present study indicates that retroviral infections still play an important role in the development of feline lymphomas in southern Brazil. 相似文献
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Zusammenfassung Einige aliphatische Aldehyde und Ketone sowie Ester von Fettsäuren wurden auf ihre Lockwirkung gegenüberIps sexdentatus geprüft. In den Test wurden außerdem die im Terpentinöl des Kiefernharzes vorhandenen Terpene d--Pinen, -Pinen, 3-Caren, Dipenten und Camphen einbezogen. Von den untersuchten Aldehyden erwies sich Propionaldehyd in der Verdünnung von 10–2 als Lockstoff. Mit Aceton wurde das gleiche Ergebnis erzielt.Bei den Estern höherer gesättigter und ungesättigter Fettsäuren konnte keine ausgesprochene Lockwirkung festgestellt werden. Mit den Äthylestern der Öl- und Linolsäure in der Verdünnung 10–4 wurden allerdings sehr unterschiedliche Ergebnisse erzielt, so daß eine Beurteilung schwierig erscheint.
Ips sexdentatus wird von Dipenten und Camphen stark angelockt. Dabei konnte für Dipenten eine Wirkung für den Konzentrationsbereich von 10–2 bis 10–6 und für Camphen von 10–2 bis 10–4 nachgewiesen werden. 相似文献
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