Single oral β-cryptoxanthin administration increases its serum concentration and enhances peripheral blood neutrophil function in Holstein cattle     

Atsushi KIMURA  Yo-Han KIM  Kazuyoshi HASHIZUME  Akira ITO  Katsuyuki MUKAI  Keiichiro KIZAKI  Shigeru SATO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(5):829

We investigated the effect of oral administration of β-cryptoxanthin (β-CRX) on its serum concentration and peripheral neutrophil functions by the chemiluminescence (CL) response in Holstein cattle. A single oral administration of β-CRX was performed for serum β-CRX concentration (0, 0.05, 0.1, or 0.2 mg/kg body weight [BW]) and for peak CL response of peripheral neutrophils (0.2 mg/kg BW). The serum β-CRX concentration was peaked on 2 days after, similar to peak CL response on 3 days after β-CRX administration. Therefore, a single oral administration of β-CRX (0.2 mg/kg BW) induces higher serum concentration and concurrently enhances bactericidal ability of peripheral neutrophils in Holstein cattle.  相似文献   

Hematological and biochemical features of postpartum fever in the heavy draft mare     

Takahiro AOKI  Yuki KIMURA  Anna OYA  Akiko CHIBA  Mitsuo ISHII  Yasuo NAMBO 《Journal of Equine Science》2016,27(1):13-16

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Geographical variation of skull morphology and its functional significances in the red-cheeked squirrel     

Endo H  Kimura J  Oshida T  Stafford BJ  Rerkamnuaychoke W  Nishida T  Sasaki M  Hayashida A  Hayashi Y 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2003,65(11):1179-1183

Skulls of the red-cheeked squirrel (Dremomys rufigenis) from various geographical locations: Malaysia (peninsular area), Vietnam (south district)-Laos, and Thailand (north district) were osteometrically examined. The skull size of the squirrels in the southern (Malaysia) population was fundamentally larger than that in the northern (Vietnam, Laos and Thailand) populations. The proportion indices indicated that the splanchnocranium was relatively longer in the Malaysia population, and that the interorbital space was narrower in Vietnam-Laos, and Thailand populations. We suggest that the long nose and laterally-oriented orbits in the skull may be better adapted for terrestrial-insectivorous life in the Malaysia population and the binocular sense facilitated by rostrally-oriented eyes contributes to the arboreal-fruit eating behavior in the two northern populations. The Malaysia population was clearly distinguished from the other populations by the principal component analysis. We suggest that the geographical barrier of the Isthmus of Kra influences the morphological variation of the skull among the squirrel populations.  相似文献   

核桃试管嫩茎生根的形态结构及激素调控研究   总被引：5，自引：0，他引：5  

王清民  彭伟秀  张俊佩  裴东 《园艺学报》2006,33(2):255-259

 以核桃品种‘新早丰’试管嫩茎为试材, 对其诱导生根过程中的形态结构及相关的生长素(IAA) 和脱落酸(ABA) 变化进行了研究。证实诱导生根过程中核桃嫩茎不定根原基发生于形成层, 特别是髓射线正对的形成层部分; 根原基起始分化期为诱导第6 天左右, 伸长期是第10天; 如果12 d之后仍放在诱导培养基中, 生根率下降, 并且出现茎基愈伤化、茎尖变黑和叶片脱落等现象; 若生根诱导10 d后转入无植物生长调节剂培养基, 培养5 d左右可见根尖突出表皮, 根系发育正常; 同时与不定根形态发生相应的内源IAA和ABA的变化是根原基的发生期和伸长期, 内源IAA出现高峰, 内源ABA呈上升趋势,IAA /ABA值在根原基的发生前为最大, 随后降低。本研究不仅从形态结构证实了二步生根法的合理性, 而且从生理学角度阐述了不定根发生的IAA /ABA调控机制。  相似文献   

Influence of feeding regime on timing of parturition in beef cattle and the relationship of vaginal temperature to parturition     

Mari AOKI  Koji KIMURA  Osamu SUZUKI 《Animal Science Journal》2006,77(3):290-299

The timing of parturition was recorded for a total of 56 beef cattle (Japanese Black × Holstein Friesian) on different dietary treatments. The rate of calving during daylight hours in cows night‐fed (18.00 hours) with a roughage diet was significantly higher than that in cows night‐fed with a high concentrate diet (79.2% vs 38.5%, P < 0.05). Subsequently, the vaginal temperature (VT) of these cows was analyzed using a cosinor method. When the feeding schedule was changed from twice daily (08.30 and 15.30 hours) to night feeding, the periodicity, the acrophase and the bathyphase, which were the parameters of the cosine curve, were unstable from the first day of night feeding until after day 6 (P < 0.05). Prior to parturition, the midline‐estimating statistic of rhythm (MESOR) and the amplitude for the cows that were fed a high‐roughage diet at night and that calved at night‐time were lower and larger, respectively, than that for the other treatments (P < 0.01). Based on these results, the time of parturition in most of the beef cows was influenced by feeding time and diet composition. Those cows that calved at night‐time in spite of night feeding had lower vaginal temperatures.  相似文献   

The effect of topical minoxidil treatment on hair follicular growth of neonatal hairless descendants of Mexican hairless dogs     

TOHRU KIMURA  & KUNIO DOI 《Veterinary dermatology》1997,8(2):107-113

The effect of daily topical minoxidil treatment on hair growth was investigated in eight neonatal hairless pups. After 21 days of minoxidil treatment, hair growth occurred in the minoxidil-treated areas of each neonatal hairless pup. The numbers of hairs in the treated areas increased as compared with that in the areas treated with vehicle only. Histological findings revealed that the skin treated with minoxidil contained many hair follicles derived from epidermal ingrowths (hair germs) projecting into the dermis. These hair follicles showed various stages of neofolliculogenesis. After 31 days of treatment, terminal hair growth was observed. In the minoxidil-untreated areas, epidermal ingrowths remained undifferentiated. These results revealed that hairless dogs developed hair growth reactions following minoxidil-treatment when such treatment is applied in the early neonatal period. Neonatal hairless pups are a useful model for evaluating the effectiveness of hair growth stimulators.  相似文献   

Comparative functional anatomy of hindlimb muscles and bones with reference to aquatic adaptation of the sea otter     

Kent MORI  Satoshi SUZUKI  Daisuke KOYABU  Junpei KIMURA  Sung-Yong HAN  Hideki ENDO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(5):571-578

Although the sea otter (Enhydra lutris) is a complete aquatic species, spending its entire life in the ocean, it has been considered morphologically to be a semi-aquatic animal. This study aimed to clarify the unique hindlimb morphology and functional adaptations of E. lutris in comparison to other Mustelidae species. We compared muscle mass and bone measurements of five Mustelidae species: the sea otter, Eurasian river otter (Lutra lutra), American mink (Neovison vison), Japanese weasel (Mustela itatsi) and Siberian weasel (M. sibirica). In comparison with the other 4 species, E. lutris possessed significantly larger gluteus, popliteus and peroneus muscles, but smaller adductor and ischiopubic muscles. The popliteus muscle may act as a medial rotator of the crus, and the peroneus muscle may act as an abductor of the fifth toe and/or the pronator of the foot. The bundles of the gluteus superficialis muscle of E. lutris were fused with those of the tensor fasciae latae muscle and gluteofemoralis muscles, and they may play a role in femur abduction. These results suggest that E. lutris uses the abducted femur, medially rotated crus, eversion of the ankle and abducted fifth digit or extended interdigital web as a powerful propulsion generator. Therefore, we conclude that E. lutris is a complete aquatic animal, possessing differences in the proportions of the hindlimb muscles compared with those in other semi-aquatic and terrestrial mustelids.  相似文献   

Variations in the morphology of Rhizomucor pusillus in granulomatous lesions of a Magellanic penguin (Spheniscus magellanicus)     

Fumiko SUZUTA  Kumiko KIMURA  Ryo URAKAWA  Yukio KUSUDA  Shogo TANAKA  Yasuko HANAFUSA  Makoto HARITANI 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(8):1029-1031

This report presents a new case of mucormycosis encountered in penguin characterized by morphological variation of hyphae and presence of sporangia with numerous sporangiospores. A 4.5-year-old Magellanic penguin (Spheniscus magellanicus) died after exhibiting anorexia, poor nutritional condition and dyspnea. Multiple nodular lesions were observed in the thoracic and abdominal regions. Histopathologically, hyphae of various sizes were seen in the lungs, air sac and nodular lesions. Myriad sporangiospores and several sporangia were observed in/around the bronchi or parabronchi. The very narrow and short hyphae in the nodules were not consistent with the characteristics of Mucorales. However, for most hyphae, including those in the nodules, sporangiospores and sporangia, immunohistochemistry revealed Mucorales-positive reactions. In addition, these fungi were identified as Rhizomucor pusillus by gene analysis.  相似文献   

Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma     

Satoshi KAMBAYASHI  Masaya IGASE  Kosuke KOBAYASHI  Ayana KIMURA  Takako SHIMOKAWA MIYAMA  Kenji BABA  Shunsuke NOGUCHI  Takuya MIZUNO  Masaru OKUDA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(11):1405-1412

Hypoxic conditions in various cancers are believed to relate with their malignancy, and hypoxia inducible factor-1α (HIF-1α) has been shown to be a major regulator of the response to low oxygen. In this study, we examined HIF-1α expression in canine lymphoma using cell lines and clinical samples and found that these cells expressed HIF-1α. Moreover, the HIF-1α inhibitors, echinomycin, YC-1 and 2-methoxyestradiol, suppressed the proliferation of canine lymphoma cell lines. In a xenograft model using NOD/scid mice, echinomycin treatment resulted in a dose-dependent regression of the tumor. Our results suggest that HIF-1α contributes to the proliferation and/or survival of canine lymphoma cells. Therefore, HIF-1α inhibitors may be potential agents to treat canine lymphoma.  相似文献   

Bone morphological analyses in Spontaneously Diabetic Torii (SDT) fatty rats     

Takeshi OHTA  Shuichi KIMURA  Masaya HIRATA  Takahisa YAMADA  Toshie SUGIYAMA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(10):1327-1330

The Spontaneously Diabetic Torii (SDT) fatty rat, a model for obese type 2 diabetes, shows bone quantitative abnormalities, namely low bone mineral density (BMD). The objective of this study was to evaluate bone morphological changes, in particular identifying the bone qualitative abnormalities, in the SDT fatty rat. Male SDT fatty rats showed increases in total trabecular area and trabecular number and decreases in trabecular thickness in cancellous bones of the proximal tibia, indicating trabecular miniaturization. The SDT fatty rat is useful for investigation of pathophysiological changes in bone quality in diabetic osteoporosis.  相似文献