Effects of Nylon and Polyglactin 910 Suture Material on Perilimbal Corneal Wound Healing in the Dog     

RENE T. van  EE dvm  MARK P. NASISSE dvm  Diplomateacvo  GAYMAN HELMAN dvm  PhD  Diplomateacvp WILLIAM SANDERS PhD 《Veterinary surgery : VS》1986,15(6):435-440

The effects of fine suture materials on corneal wound healing in the dog were studied. In 20 dogs, standardized perforating perilimbal clear corneal wounds were made and closed with either monofilament Polyglactin 910 or nylon. Five dogs each were euthanized 8,12,16, and 21 days postoperatively. Results of gross, biomicroscopic, and histologic examinations at 8,12,16, and 21 days showed nylon and Polyglactin 910 to cause similar inflammatory responses. Epithelialization and suppuration around the suture tracts were observed more frequently when Polyglactin 910 was used. Both materials were associated with a foreign body (granulomatous) response. There was no loss of wound integrity with either material. Strengths of the incised corneal tissues with and without the sutures intact were determined. At day 16 postsurgery, there was a statistically significant difference in tissue strengths between cases in which sutures were and were not intact. This difference was not apparent at 21 days postsurgery, which suggested that the suture dependent phase ends between the 16th and 21st postsurgical days. In addition, at day 16 there was no statistical difference between the tissue strength of wounds sutured with nylon or Polyglactin 910. Corneal suture materials studied should remain in place for at least 16 days, and absorbable material is only appropriate if it retains tensile strength for 16 days.  相似文献   

Haematological and biochemical reference values for grazing Saanen goats     

S MCDOUGALL  EE LEPHERD  S SMITH 《Australian veterinary journal》1991,68(11):370-372

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Nerve growth factor gene expression in the developing rat brain   总被引：31，自引：0，他引：31  

T H Large  S C Bodary  D O Clegg  G Weskamp  U Otten  L F Reichardt 《Science (New York, N.Y.)》1986,234(4774):352-355

The regulation of nerve growth factor (NGF) protein and NGF messenger RNA (mRNA) in the developing rat brain has been studied to assess the hypothesis that NGF supports the differentiation of cholinergic neurons in the basal forebrain. In the adult, the major targets of these neurons, the hippocampus and neocortex, contain the highest concentrations of NGF mRNA, but comparatively low ratios of NGF protein to its mRNA. In contrast, a high concentration of NGF protein and a low concentration of NGF mRNA were seen in the basal forebrain, consistent with retrograde transport of NGF protein into this region from the neocortex and hippocampus. In these two target regions NGF and NGF mRNA were barely detectable at birth, their concentrations increased to a peak at day 21, and then NGF mRNA, but not NGF protein, declined threefold by day 35. NGF accumulation in the basal forebrain paralleled that in the target regions and preceded an increase in choline acetyltransferase, suggesting that the differentiation of cholinergic projection neurons is indeed regulated by retrogradely transported NGF. In addition, high ratios of NGF protein to NGF mRNA, comparable to that in the basal forebrain, were seen in the olfactory bulb and cerebellum, suggesting that NGF may be transported into these regions by unidentified neurons.  相似文献   

EXTENT OF PROTECTIVE SPRAYING AND HAULM DESTRUCTION ON POTATO CROPS IN GREAT BRITAIN, 1952–60     

E. C. Large  Rachel A.  Waines 《Plant pathology》1961,10(3):96-100

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LOSSES CAUSED BY POTATO BLIGHT IN ENGLAND AND WALES   总被引：4，自引：4，他引：0  

E. C. Large 《Plant pathology》1958,7(2):39-48

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GROWTH STAGES IN CEREALS ILLUSTRATION OF THE FEEKES SCALE   总被引：40，自引：33，他引：7  

E. C. Large 《Plant pathology》1954,3(4):128-129

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SURVEY OF COMMON SCAB OF POTATOES IN GREAT BRITAIN, 1952 AND 1953   总被引：12，自引：12，他引：0  

E. C. Large  June K.  Honey 《Plant pathology》1955,4(1):1-8

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LAMB PRODUCTION FROM TWO SIMPLE MIXTURES UNDER TWO METHODS OF MANAGEMENT     

R. V. Large  J. C. Tayler 《Grass and Forage Science》1956,11(4):216-223

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John Thomas Vaughan Large Animal Teaching Hospital     

John Thomas Vaughan Large Animal Teaching Hospital 《Journal of Equine Veterinary Science》2004,24(12):545-548

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Vertebral body osteomyelitis in the horse   总被引：1，自引：0，他引：1  

M D Markel  J E Madigan  C A Lichtensteiger  S M Large  W J Hornof 《Journal of the American Veterinary Medical Association》1986,188(6):632-634

Over a 4-year period, vertebral body abscess was diagnosed in 5 young cattle. The laboratory findings in most of these cases did not suggest a diagnosis of vertebral body abscess. The most important basis for diagnosis of this condition was a thorough neurologic examination. In 4 cases, necropsy revealed abscesses in the lungs or thoracic cavity as well, suggesting that a history of pneumonia preceding paresis may favor the diagnosis of vertebral body abscess.  相似文献