Ovine hereditary chondrodysplasia (spider syndrome) in Suffolk lambs   总被引：1，自引：0，他引：1  

PH PHILLIPS  CM BUNN  CE ANDERSON 《Australian veterinary journal》1993,70(2):73-74

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Equine Cryptorchidism: Pre-surgical Considerations and Surgical Management     

J. N. MOORE D.V.M.    J. H. JOHNSON D.V.M.  M.S.  L G. TRITSCHLER D.V.M.  M.S.  H. E. GARNER D.V.M.  PH.D. 《Veterinary surgery : VS》1978,7(2):43-47

Horses with undescended testes are frequently presented to the veterinary surgeon for castration. The pertinent pre-operative evaluations and diagnostic procedures that should be made prior to either surgical intervention or referral of such cases are outlined. Several accepted anesthetic and surgical techniques are similarly reviewed. Case histories of 58 horses referred during a two year period are reviewed and correlated with the findings of a recent study of equine testicular development and descent.  相似文献   

Nodules caused by demodex-like mites in the skin of tiger quolls (Dasyurus maculatus)     

PH HOLZ 《Australian veterinary journal》1998,76(1):59-60

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A clinicopathologic and ultrastructural study of undifferentiated malignant tumors of the oral cavity in dogs     

A K Patnaik  P H Lieberman  R A Erlandson  E G MacEwen  A I Hurvitz 《Veterinary pathology》1986,23(2):170-175

Undifferentiated malignant tumors of the oral cavity were diagnosed in six dogs under 2 years of age. The dogs were examined because of pain and swelling of the upper molar or premolar areas. In all six dogs, the tumors were initially misdiagnosed as infections or carnasal abscesses. The differential diagnosis included malignant lymphoma, osteosarcoma, mesenchymal chondrosarcoma, embryonal rhabdomyosarcoma, and malignant melanoma. Electron microscopy of three neoplasms showed that there were no specific features characteristic of carcinoma or sarcoma. Immunoperoxidase studies for cytokeratins, epithelial membrane antigen, actin, myosin, desmin, and vimentin were also negative. We conclude that these tumors be designated undifferentiated malignant tumors of the oral cavity until histogenesis is established.  相似文献   

Tropical Tree Growth and Longevity: Validation of Growth Simulation,a Bootstrapping Model     

Mariby Cruz  Milton Lieberman 《Journal of Sustainable Forestry》2020,39(7):674-691

ABSTRACT

Growth Simulation, an analytical modeling technique, has been increasingly used in ecological studies and practical forestry applications where dendrochronology is not applicable. The technique uses randomly sampled diameter increments from tagged trees over a known time interval to assemble a statistical sample of lifetime growth trajectories. We carried out a validation of Growth Simulation using a temperate species in order to compare indirect model outputs with direct tree ring analysis. Rings were measured on sample disks cut from 55 pine branches ranging in age from 8–36 years. Assessments included lifetime growth rates, growth rate with respect to diameter and age, periodic annual increment (PAI), cross-referencing of rings by date, and autocorrelation of growth over successive periods. Tree ring analysis and Growth Simulation showed close correspondence for all parameters tested (maximum, median, and minimum growth rates; longevity estimates). Growth Simulation is found to be a robust and informative technique for studies of tropical tree growth, and is especially useful where analysis of tree rings is not feasible or when bootstrapping analysis of ring data is of interest.  相似文献   

Esophageal neuroendocrine carcinoma in a cat     

A K Patnaik  R A Erlandson  P H Lieberman 《Veterinary pathology》1990,27(2):128-130

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Whither or wither microbicides?     

Grant RM  Hamer D  Hope T  Johnston R  Lange J  Lederman MM  Lieberman J  Miller CJ  Moore JP  Mosier DE  Richman DD  Schooley RT  Springer MS  Veazey RS  Wainberg MA 《Science (New York, N.Y.)》2008,321(5888):532-534

After disappointing results from all efficacy trials conducted to date, the field of microbicides research now faces substantial challenges. Poor coordination among interested parties and the choice of nonvalidated scientific targets for phase III studies have hampered progress and created mistrust about the use of microbicides as a method to prevent HIV-1 sexual transmission. Although new promising strategies are available, there will need to be serious reappraisals of how decisions are made to advance the next generations of candidates into clinical trials, and the use of appropriate animal models in this process will be critical.  相似文献   

Polymorphism of heavy-chain genes in immunoglobulins of wild mice   总被引：3，自引：0，他引：3  

R Lieberman  M Potter 《Science (New York, N.Y.)》1966,154(748):535-537

The serums of 123 wild mice from six different geographic locations in the United States contain five of the six known heavy-chain antigenic determinants that have been identified in immunoglobulin of inbred laboratory strains of mice. On the basis of the distribution of determinants in inbred strains,44 of the mice were judged to be heterozygotes of various combinations and two had combinations of determinants that were unusual and could only have occurred in laboratory inbred mice by recombination.  相似文献   

Quantitative analysis of culture using millions of digitized books   总被引：1，自引：0，他引：1  

Michel JB  Shen YK  Aiden AP  Veres A  Gray MK;Google Books Team  Pickett JP  Hoiberg D  Clancy D  Norvig P  Orwant J  Pinker S  Nowak MA  Aiden EL 《Science (New York, N.Y.)》2011,331(6014):176-182

We constructed a corpus of digitized texts containing about 4% of all books ever printed. Analysis of this corpus enables us to investigate cultural trends quantitatively. We survey the vast terrain of 'culturomics,' focusing on linguistic and cultural phenomena that were reflected in the English language between 1800 and 2000. We show how this approach can provide insights about fields as diverse as lexicography, the evolution of grammar, collective memory, the adoption of technology, the pursuit of fame, censorship, and historical epidemiology. Culturomics extends the boundaries of rigorous quantitative inquiry to a wide array of new phenomena spanning the social sciences and the humanities.  相似文献   

2-chain immunoglobulin A molecules: abnormal or normal intermediates in synthesis   总被引：4，自引：0，他引：4  

R Lieberman  J F Mushinski  M Potter 《Science (New York, N.Y.)》1968,159(821):1355-1357

Immunoglobulin A (gammaA) myeloma proteins secreted by plasma-cell tumors of mice are of two types, a common four-chain molecule and a rare two-chain (3.9S) molecule. The close similarity between two-chain gammaA molecules and four-chain gammaA molecules and their polymers is demonstrated in tryptic peptide maps of isolated polypeptide chains and by precipitin reactions with rabbit antiserums to gammaA immzunoglobulins. However, a difference between these two types is distinguishable with homologous antiserums. Homologous antiserums to two-chain gammaA immunoglobulins are specific and do not cross-react with four-chain gammaA immutnoglobulins.  相似文献