Haematological and biochemical investigations of diseased koalas (Phascolarctos cinereus)     

PJ CANFIELD  ME O'NEILL†  EF SMITH† 《Australian veterinary journal》1989,66(9):269-272

Haematological and biochemical investigations were performed on 14 koalas with uncomplicated cystitis, 8 with complicated cystitis, 8 with conjunctivitis, 8 with lymphosarcoma, and 14 with miscellaneous diseases. Changes were limited and inconsistent in individual koalas with uncomplicated cystitis and conjunctivitis. In contrast, individual koalas with complicated cystitis were more likely to have anaemia, leukocytosis due to neutrophilia, hypoproteinaemia due to hypoalbuminaemia, and azotaemia due to elevated urea concentration. Although these changes were non-specific they did allow assessment of prognosis for survival and response to treatment. Koalas with lymphosarcoma were invariably anaemic, leukaemic, azotaemic and hypoalbuminaemic. Elevated enzymes (aspartate transaminase [AST]. lactate dehydrogenase [LD] and gamma glutamyl transferase [GGT]) were more common in koalas with lymphosarcoma. Koalas affected by miscellaneous conditions showed variable changes but once again anaemia, leukocytosis, azotaemia, elevated AST and LD, and hypoalbuminaemia were not uncommon. On the basis of these findings a minimal profile is suggested for the investigation of sick koalas and would include haematocrit, total and differential leukocyte counts, urea, total protein and albumin concentrations and AST, GGT and LD activities.  相似文献   

Successful treatment of severe hypokalemia in a dog with acute kidney injury caused by leptospirosis          下载免费PDF全文

Ashley E. Allen DVM  Gareth J. Buckley MA  VetMB  DACVECC  DECVECC  Michael Schaer DVM  DACVIM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2016,26(6):837-843

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Presentation,clinical pathological and post‐mortem findings in three related Scottish terriers with ligneous membranitis          下载免费PDF全文

S. L. Mason  C. Fisher  L. Ressel  N. X. Bommer  L. M. Buckley  T. Nuttall 《The Journal of small animal practice》2016,57(5):271-276

Ligneous conjunctivitis and gingivitis were diagnosed in three related Scottish terrier dogs presented for investigation of severe conjunctivitis and respiratory signs. Hypoplasminogenaemia was confirmed in one of the three affected dogs. Supportive treatment was not effective, and the dogs died or were euthanased because of the disease. Post‐mortem analysis of two of the dogs revealed multiple abnormalities including severe proliferative fibrinous lesions affecting the conjunctiva, gingiva, trachea, larynx and epicardium and multiple fibrous adhesions throughout the thoracic and abdominal cavities. One dog had internal hydrocephalus and lacked a cerebellar vermis. Ligneous membranitis was confirmed on histopathology. This is a rare condition in dogs but an important differential diagnosis for severe conjunctivitis and gingivitis.  相似文献   

Resistance studies of erythromycin and rifampin for Rhodococcus equi over a 10-year period     

Buckley T  McManamon E  Stanbridge S 《Irish veterinary journal》2007,60(12):728-731

This study sought to determine whether an increase in resistance of Rhodococcus equi to the antibiotics rifampin and erythromycin occurred over a 10-year period. This was carried out by the use of E test strips for rifampin and erythromycin to determine the MIC (minimum inhibitory concentration) values of Rhodococcus equi to this combination of antibiotics.The findings of this study indicated that there was an increase in resistance of Rhodococcus equi to rifampin and erythromycin over the 10-year period. The MIC for rifampin increased from 0.081 μg/ml in 1996 to 0.187 μg/ml in 2006 and from 0.258 μg/ml for erythromycin during the years prior to 2000 to 0.583 μg/ml in 2006.This finding suggests that there may be a problem in the treatment of Rhodococcus equi infections in foals in the future, particularly as the number of drugs available for treatment of Rhodococcus equi infection is limited because of the intracellular capabilities of this bacterium. Antibiotics used in its treatment have to be able to penetrate the polysaccharide cell wall of Rhodococcus equi as well as the alveolar macrophages in which the bacterium is capable of surviving.  相似文献   

Surveillance of dairy production holdings supplying raw milk to the farmhouse cheese sector for Escherichia coli O157, O26 and O111     

Murphy M  Buckley JF  Whyte P  O'Mahony M  Anderson W  Wall PG  Fanning S 《Zoonoses and public health》2007,54(9-10):358-365

Clinically healthy domestic animals can harbour Escherichia coli O157 and other verocytotoxigenic E. coli (VTEC) strains in their faeces. Milk filters can be used to microbiologically monitor direct milk secretion and environmental contamination for these pathogens. The aim of this study was to establish baseline data on the prevalence and characteristics of VTEC organisms in lactating animals (bovine, ovine and caprine) supplying milk to the farmhouse cheese sector, with particular emphasis on serogroups O157, O111 and O26. Fifty-six bovine, 13 caprine and 5 ovine herds/flocks, the majority of which supplying milk for farmhouse cheese production, were surveyed from May 2004 to July 2005. Milk filters were analysed by immunomagnetic separation followed by PCR, on a serogroup-specific basis for E. coli O157, O26 and O111. Positive isolates were examined using a multiplex PCR protocol, for their potential to produce verocytotoxins (vt1/vt2), the haemolysin-encoding gene (hlyA) and the gene encoding attaching and effacement (eae). Five verocytotoxigenic and 22 non-virulent E. coli O157 isolates were detected. Seventeen E. coli O26 isolates were also detected, four of which were verocytotoxigenic, seven isolates contained the eae gene only and six isolates were devoid of any of the virulence factors. The VTEC O157 and O26 isolates contained the hlyA and eae genes along with the verocytotoxin genes. No E. coli O111 isolates were detected. Some of the herds were positive on more than one occasion and multiple E. coli serogroups were isolated from the same milk filter sample. Although all food products tested were VTEC negative, routine surveillance for such pathogens in raw milk/raw milk products is of public health importance. Herd-level surveillance along with subsequent risk management action may be a cost-effective component of risk reduction strategies for food production, drinking water supplies and the protection of public health.  相似文献   

Molecular surveillance of the incidence of Taylorella equigenitalis and Pseudomonas aeruginosa from horses in Ireland by sequence-specific PCR     

Moore JE  Buckley TC  Millar BC  Gibson P  Cannon G  Egan C  Cosgrove H  Stanbridge S  Anzai T  Matsuda M  Murphy PG 《Equine veterinary journal》2001,33(3):319-322

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Molecular detection and characterisation of Taylorella equigenitalis     

Moore JE  Millar BC  Matsuda M  Anzai T  Buckley T 《The Veterinary record》2003,152(17):543-544

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Empirical algebraic modelling of live weight of Irish dairy cows over lactation     

N. Quinn  L. Killen  F. Buckley 《Livestock Science》2006,103(1-2):141-147

The aim of this study is to derive an equation that has the ability to model live weight of Irish dairy cows over lactation. The data set consisted of 6899 cows from 63 herds, of which 428 were from experimental herds and 6471 cows were from commercial herds. An initial examination focussed on time series techniques, as the data are of a time series nature. Splines were also examined to determine the dimensions of a model required to represent the data. As an incomplete gamma function, which was previously used to model milk yield, has been used in other studies to model live weight, various milk yield models were investigated. Finally, live weight changes between two calvings were modelled as a function of age, days in milk and pregnancy. As multicollinearity was evident in this function, the variance inflation factor was examined and principal component analysis was carried out on the variables responsible for multicollinearity. The proposed live weight model has a better fit than previous models, weak multicollinearity and the residuals are homoskedastic, independent and normally distributed. This live weight model therefore provides an acceptable level of accuracy in representing the shape of the live weight curve for Irish dairy cows and can be easily modified for different environmental scenarios.  相似文献   

Simulation study of the competitive ability of erect, semi-erect and prostrate cowpea (Vigna unguiculata) genotypes   总被引：1，自引：1，他引：1  

G WANG  ME MCGIFFEN JR  JL LINDQUIST†  JD EHLERS  & I SARTORATO‡ 《Weed Research》2007,47(2):129-139

Ecophysiological simulation models provide a quantitative method to predict the effects of management practices, plant characteristics and environmental factors on crop and weed growth and competition. The INTERCOM interplant competition model was parameterised, calibrated by monoculture data for three cowpea (Vigna unguiculata) genotypes that differed in growth habit, common sunflower (Helianthus annuus) and common purslane (Portulaca oleracea), and used to simulate competition of cowpea cover crops with sunflower or purslane. The simulation results were compared with observations from field competition experiments in 2003 and 2004. INTERCOM more accurately simulated actual field data for the competition of cowpea genotypes and sunflower than companion field experiments for the competition of cowpea and purslane. The validated simulation model of cowpea and sunflower at two densities was used to study the effects of cowpea growth habit on final biomass production of cowpea and sunflower. The model suggested that erect growth habit was more competitive than semi‐erect and prostrate growth habit, when cowpea genotypes were grown with sunflower. Cowpea leaf area distribution was important to higher cowpea biomass production, while cowpea height growth was important to reduce sunflower biomass. Our simulation approach is suggested as a method for crop breeders to gauge the likely success of selection for competitive crops before undertaking expensive long‐term breeding experiments.  相似文献   

Diagnosis and therapy     

ME BERNAYS 《Australian veterinary journal》1998,76(5):316-316

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