Book reviews     

Marilyn Holly  Paul Lasley  Ward Churchill 《Agriculture and Human Values》1991,8(3):73-78

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Isolation and characterization of the eighth component of the bovine complement system     

Menger M  Sowery RD  Aston WP 《American journal of veterinary research》1999,60(12):1474-1477

OBJECTIVE: To isolate and characterize the eighth component of the complement system (C8) in cattle. SAMPLE POPULATION: Fresh plasma obtained from beef cattle. PROCEDURES: Plasma samples were fractionated, using sequential precipitation and ion-exchange and gel-filtration chromatography, to yield C8. The protein was identified throughout the procedure on the basis of its hemolytic function. Electrophoresis in polyacrylamide gels was used to determine molecular weight and composition of polypeptide chains. Reconstitution of classical and alternative complement pathways was used to characterize the hemolytic function of bovine C8. RESULTS: The bovine C8 protein consisted of a disulfide-bonded alpha-gamma heterodimer that was noncovalently associated with a beta chain. Apparent molecular weight of the alpha, beta, and gamma chains under reducing conditions were 66, 61, and 23 kd, respectively. In the classical pathway of activation, bovine C8 and the ninth component of the complement system (C9) had species incompatibility with human C8 and C9 on sheep erythrocyte target cells. CONCLUSIONS: A simple 4-step fractionation procedure provided good yield of bovine C8 from plasma. The isolated protein was structurally comparable to C8 from other species. Purified bovine C8 may be useful in functional hemolytic assays to investigate the roles of complement-mediated lysis in the pathogenesis of inflammatory diseases and the killing of susceptible microorganisms.  相似文献   

Not classical homeopathy          下载免费PDF全文

Drosdovech M  Neumann S  Evans D  Blake S  Peck LS  Yearout DR  Ulbrich B  Facinelli J  Delgado R  Hoberg L  Harman J  Sthamann M  Lindsay M  Kwong H  Lampru A  Lamb J  Stagmeier K  Doyle JL  Elliot J  Siemon L 《The Canadian veterinary journal. La revue veterinaire canadienne》2002,43(12):908-909

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Assessing performance of feedlot operations using epidemiology.     

Marilyn J Corbin  Dee Griffin 《Veterinary Clinics of North America: Food Animal Practice》2006,22(1):35-51

The progressive feedlot veterinarian must be well versed not only in individual production animal medicine, but also in population-based medicine. Feedlot health programs must be goal oriented, and evaluation of these goals is accomplished through diligent use of record systems and analytic evaluation of these record systems. Basic feedlot monitoring parameters include health and economic parameters in addition to the use of bench marking parameters between and among feed yards. When these parameters have significant changes, steps should be initiated to begin field investigations. Feedlot epidemiology uses several novel applications such as partial budgeting, risk assessment, and packing plant audits to provide scientifically sound and economically feasible solutions for the feeding industry.  相似文献   

A SYMPOSIUM ON THE CALCULUS OF VARIATIONS     

Menger K 《Science (New York, N.Y.)》1937,85(2210):456-458

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Fatal Gastrointestinal Infection with ‘Flexispira rappini’‐Like Organisms in a Cat     

A. Kipar  M. Weber  S. Menger  D. Harmsen 《Zoonoses and public health》2001,48(5):357-365

A 4‐month‐old male British Blue cat with catarrhal to haemorrhagic enteritis showed massive colonization of the stomach, small intestine and caecum with spiral‐shaped bacilli. In the stomach, organisms were located in foveolae and gland lumina and within unaltered and degenerate epithelial cells. Inflammatory infiltration was moderate and T cell dominated. In the intestine, bacilli were found in the gut lumen, between villi, in crypt lumina and within epithelial cells. Degeneration of crypt epithelial cells as well as crypt dilation and moderate to massive macrophage‐dominated infiltration of the mucosa and submucosa were observed. Immunohistochemically, bacilli were positive with an antibody against Helicobacter. Ultrastructurally, the organisms strongly resembled ‘Flexispira rappini’, a spiral‐shaped Helicobacter species known as a normal intestinal colonizer in dogs and mice.  相似文献   

Considering the when and the where of eating     

Tseng M 《Public health nutrition》2005,8(3):221-222

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A virus in a fungus in a plant: three-way symbiosis required for thermal tolerance   总被引：2，自引：0，他引：2  

Márquez LM  Redman RS  Rodriguez RJ  Roossinck MJ 《Science (New York, N.Y.)》2007,315(5811):513-515

A mutualistic association between a fungal endophyte and a tropical panic grass allows both organisms to grow at high soil temperatures. We characterized a virus from this fungus that is involved in the mutualistic interaction. Fungal isolates cured of the virus are unable to confer heat tolerance, but heat tolerance is restored after the virus is reintroduced. The virus-infected fungus confers heat tolerance not only to its native monocot host but also to a eudicot host, which suggests that the underlying mechanism involves pathways conserved between these two groups of plants.  相似文献   

Origin and evolution of prebiotic organic matter as inferred from the Tagish Lake meteorite     

Herd CD  Blinova A  Simkus DN  Huang Y  Tarozo R  Alexander CM  Gyngard F  Nittler LR  Cody GD  Fogel ML  Kebukawa Y  Kilcoyne AL  Hilts RW  Slater GF  Glavin DP  Dworkin JP  Callahan MP  Elsila JE  De Gregorio BT  Stroud RM 《Science (New York, N.Y.)》2011,332(6035):1304-1307

The complex suite of organic materials in carbonaceous chondrite meteorites probably originally formed in the interstellar medium and/or the solar protoplanetary disk, but was subsequently modified in the meteorites' asteroidal parent bodies. The mechanisms of formation and modification are still very poorly understood. We carried out a systematic study of variations in the mineralogy, petrology, and soluble and insoluble organic matter in distinct fragments of the Tagish Lake meteorite. The variations correlate with indicators of parent body aqueous alteration. At least some molecules of prebiotic importance formed during the alteration.  相似文献   

Book reviews     

Marilyn Holly  Carla A. Kirts  Yvonne Everett  Jan L. Flora  David O. Hansen  Cornelia Butler Flora  John A. Hayward  David Haenke  Alessandro Bonanno 《Agriculture and Human Values》1988,5(4):57-78

Marilyn Holly is an Associate Professor of Philosophy at the University of Florida. Her special interests include political philosophy, ethics and ecology, Jungian thought, and Native American spirituality in its relation to the environment. She is currently at work on a monograph-length piece on the latter topic. She has taught an undergraduate course in ethics and ecology, and plans to do so again. The following essay emerged from her search for a suitable text for such a course.  相似文献