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McIntosh DW 《The Canadian veterinary journal. La revue veterinaire canadienne》1982,23(10):291-294,295
Forty-four files of cats diagnosed as having feline leprosy were reviewed. All except one were from along the Pacific coast in the Province of British Columbia. The majority of cats were between one and three years of age and there was an increase in the number of diagnosis during the winter months.
Two types of granulomatous responses similar to the tuberculoid and lepromatous phases of human leprosy were recognized. In spite of the overall similarities in the cellular response to human leprosy there were, however, significant differences such as areas of caseous necrosis and constant lack of nerve involvement. Still as there is presently no way to prove that Mycobacterium leprae is not the cause of feline leprosy the public health significance remains uncertain
The treatment of choice would appear to be surgical removal.
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SUMMARY Urolithiasis is a disease of multifactorial origin. Prominent amongst the causes of disease outbreaks are nutritional factors. Alteration of diet is probably one of the most effective means of prevention, depending of course on the nature of the uroliths formed. In this regard analysis of the stones formed is an essential prelude to understanding, adequately treating the disease and preventing its recurrence. 相似文献
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K. S. McIntosh 《Australian veterinary journal》1971,47(8):383-387
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Parker S Campbell J McIntosh K Gajadhar A 《The Canadian veterinary journal. La revue veterinaire canadienne》2003,44(9):732-734
The diagnostic test for Tritrichomonas foetus in bulls is microscopic examination of cultured preputial samples. Trichomonads other than T. foetus can be present in a preputial sample. Both a staining technique and a polymerase chain reaction assay were useful in differentiating between T. foetus and another trichomonad observed in samples from virgin bulls. 相似文献
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In mature Merino rams, nutrition is one of the external cues that most strongly affects the reproductive centres of the preoptic-hypothalamic continuum. The signalling pathways that link dietary status and the activity of the neurones that produce gonadotrophin-releasing hormone signals are thought to be partly hormonal in nature to reflect the amount of body reserves. Among the hormones thought to be involved are insulin and leptin. This study tested whether recombinant bovine leptin infused (0.4 microg/h) into the third cerebral ventricle would stimulate pulsatile luteinizing hormone (LH) secretion in mature Merino rams when their energy status was low or decreasing, during both chronic (fasting) and acute reductions of energy balance. Leptin may interact with other hormones that depend on energy availability, so we also monitored changes in circulating concentrations of insulin, thyroid hormones, growth hormone, prolactin and adrenocorticotrophin. Overall, our data do not support this hypothesis. The dietary regimes induced clear responses in the metabolic profiles of the animals but there was no clear effect of central leptin administration on LH pulse frequency. The relationships between the hormonal systems measured in the present study add weight to the contention that leptin plays only a permissive role in the nutritional control of the reproductive axis and that other hormonal signals (particularly insulin) or pathways are acting in concert with leptin to stimulate the reproductive axis. 相似文献
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Detection of Porcine circovirus type 2 viremia and seroconversion in naturally infected pigs in a farrow-to-finish barn 
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下载免费PDF全文 Kathleen A. McIntosh John C.S. Harding John A. Ellis Greg D. Appleyard 《Canadian journal of veterinary research》2006,70(1):58-61
Porcine serum was assayed by 2 polymerase chain reaction (PCR) protocols (nested PCR [nPCR] and non-nested PCR) and a competitive enzyme-linked immunosorbent assay to determine when Porcine circovirus type 2 (PCV2) viremia and a rise in the serum level of PCV2-specific antibody occurred in pigs raised in a large Canadian farrow-to-finish barn. Eight serial blood samples were collected from each of 40 pigs from 5 to 156 (+/- 1.5) d of age; 6 pigs were removed from the study for various reasons at various times. Viremia was not detected in the samples collected before 72 d of age but was detected in those collected on or after 72 d: of 33 pigs, 7 (21%) had only 1 serum sample positive for PCV2 DNA by nPCR after day 72; 11 (33%) were intermittently positive by nPCR, non-nested PCR, or both between 72 and 156 d; and the remaining 15 (45%) were repeatedly positive (in 2 to 4 samples). The level of serum antibody against PCV2 declined after weaning and increased between 72 and 107 d of age, only after PCV2 was detected in serum. Our results show that PCV2 viremia persists in the presence of elevated levels of PCV2-specific antibody. 相似文献