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An outbreak of a disease characterised by very high mortality occurred in a group of nine calves (1B4 months old) in a zero-grazing unit 2-3 weeks after an introduction of an apparently healthy alien sheep into the calf pen. Five of the six calves which contracted the disease died. The main clinical signs observed were marked depression, persistently high body temperature (40,5-41,5 degrees C), copious mucopurulent nasal and ocular discharges, dyspnoea, bilateral keratoconjunctivitis with corneal opacity, enlargement of the superficial lymph nodes and marked erythema and/or superficial erosions of the buccal mucosae. At necropsy there were lesions in the upper respiratory and digestive tracts, lymph nodes, brain, eyes, liver, kidneys and the urinary bladder.The lesions were histopathologically characterized by fibrinoid vasculitis which was accompanied by lymphocytic infiltration in the parenchyma of the affected tissues. Based on the evidence of contact between the calves and the recently introduced foreign sheep, the characteristic clinical signs and histopathological findings, a diagnosis of sheep-associated malignant catarrhal fever was made. 相似文献
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A 4-month-old Thoroughbred filly presented for abdominal pain was diagnosed with a T-shaped malformation of the ventral colon at exploratory laparotomy. Following resection and anastomosis of the large colon, no further episodes of abdominal pain occurred during a 12-month follow-up. Acute dehiscence of the linea alba occurred as a complication of the initial laparotomy, but was successfully managed following additional surgical repair. T-shaped malformation of the ventral colon has not previously been reported and is considered a congenital malformation of mesocolon formation. 相似文献
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Blood samples were taken at weekly intervals from 54 dairy cows (mainly Friesians and Jerseys) during the periods 8 weeks before and 8 weeks after calving. The cows were divided into two age groups; group 1 consisting of 26 cows aged 2 1/2 years and group 2 consisting of 28 cows aged 5–9 years. The changes in the erythrocyte sodium (ENa) and the erythrocyte potassium (EK) concentrations before and after calving were expressed as the slopes for each component regressed on weeks. In the older cows the concentration of ENa decreased (p<0.05) while that of EK increased (p<0.05) after calving. Both the ENa and EK concentrations varied significantly (p<0.01) between cows in the two age groups. The prepartum and postpartum ENa and the postpartum EK concentrations varied significantly (p<0.05) between weeks. EK type did not influence the changes in ENa or EK concentrations before or after calving. 相似文献
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Objective To determine the regional incidence and effectiveness of treatment of failure of passive transfer (FPT) in foals. Design A study of disease incidence. Animals Eighty-eight foals and 57 mares from four studs in the practice area of the Rural Veterinary Centre were tested. Procedure Foals were tested for their serum IgG and total serum protein (TSP) concentration within the first 72 hours of life. Colostrum was collected from mares and specific gravity determined. FPT and partial failure of passive transfer (PFPT) of immunoglobulins was diagnosed when serum IgG concentrations were < 4 g/L and 4 to 8 g/L respectively. Owners of foals diagnosed with FPT were offered treatment with 1 to 2 L plasma (TSP > 70 g/L); 9 (64%) of the affected foals were treated. Results Fourteen foals (16%) had FPT whereas 15 (17%) had PFPT. There were significant differences between the mean TSP concentration in foals with FPT (42.6 ± 4.2 g/L), PFPT (48.1 ± 3.9 g/L) and those acquiring adequate passive immunity (58.9 ± 5.5 g/L) (P < 0.01). Sixteen (29%) mares had pre-suck colostral specific gravity < 1.060 and 12 (71%) foals raised by these mares had FPT or PFPT. The incidence of severe disease (categorised by a sepsis score > 11, positive culture of bacteria from blood or disease requiring hospitalisation) in all foals in the first 2 months of life was 10%. However, none of the nine foals with FPT that received plasma experienced severe disease. In contrast, foals with PFPT had an increased susceptibility to severe disease (P < 0.001) when compared with normal foals. Conclusion Treatment of foals with FPT may reduce the subsequent incidence of severe disease. Pre-suck colostral specific gravity and foal TSP may be used to predict the likelihood of FPT and PFPT. Even though the number of foals studied is small the results highlight the importance of optimal management practices in reducing the incidence of FPT and disease associated with this process. 相似文献
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BC Schimming PFF Pinheiro R de Matteis CM Machado RF Domeniconi 《Reproduction in domestic animals》2015,50(4):617-624
Aquaporins (AQPs) are essential membrane protein channels for the transport of water across membranes. Fluid movement in the epididymis is important for modulation of the luminal environment, in which sperm mature and reside. This study was designed to understand the morphology and localization of AQPs in ram efferent ducts (ED) and epididymis. For this purpose, the epididymis of seven animals were removed for histologic and immunohistochemical analyses. AQP1 immunoreactivity was observed in the apex of the ED, and AQP9 was found adjacent to the nuclei of the epithelial cells of the ED. The epithelial lining of ram epididymis is pseudostratified columnar and presents principal, basal, apical and narrow cells. In the initial segment (IS), a moderate reaction for AQP1 was observed in the apical cytoplasm of epithelial cells. An intense reactivity for AQP1 was noted over the microvilli of principal cells and in spermatozoa in the caput. In the corpus and cauda, AQP1 was noted only over the endothelial cells of vascular channels located in intertubular spaces. A weak‐to‐moderate reaction for AQP9 was observed in the nuclei of epithelial cells in the IS, caput and corpus of the epididymis. In the cauda, an intense reaction to AQP9 was observed in the epithelial border. In the IS, caput and corpus, the reactivity for AQP9 differed from those observed in domestic animals. The cauda showed a pattern similar to that previously described. These results indicate that AQPs 1 and 9 have reversed locations and roles in rams, suggesting activity variations related with fluid and solute absorption throughout the epididymis. 相似文献
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A 2-year-old Thoroughbred gelding was evaluated for a grade 3 out of 5 unilateral hind limb lameness. Flexion of the right hock and stifle joints (spavin test) exacerbated the lameness. Response to intra-articular and perineural anaesthesia isolated the source of lameness to the tarsocrural area, despite an absence of tarsocrural joint effusion. Routine radiographic examination of the hock did not reveal any significant abnormalities. Skeletal nuclear scintigraphic evaluation revealed a focal region of increased bone activity in the proximal medial trochlear ridge of the talus. Flexed lateromedial radiographic views identified three discrete semicircular lytic lesions at the proximal articular margin of the medial trochlear ridge of the talus. Conservative management of the lesions was associated with a successful return to racing. The location and appearance of the osteochondral lesions of this report have not been previously reported and may be a manifestation of developmental orthopaedic disease and abnormal endochondral ossification. Nuclear scintigraphy and flexed lateromedial radiographic views facilitated identification of the lesions. This radiographic view is recommended when lameness is isolated to the tarsocrural joint and standard radio-graphic projections fail to identify a cause. 相似文献