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In vitro evaluation of a simulated pneumoperitoneum environment using carbon dioxide on canine transitional cell carcinoma 
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Williams LE Gliatto JM Dodge RK Johnson JL Gamblin RM Thamm DH Lana SE Szymkowski M Moore AS;Veterinary Cooperative Oncology Group 《Journal of the American Veterinary Medical Association》2003,223(6):825-831
OBJECTIVE: To characterize the signalment, clinical signs, biological behavior, and response to treatment of carcinoma of the apocrine glands of the anal sac in dogs. DESIGN: Retrospective study. ANIMALS: 113 dogs with histologically confirmed carcinoma of the apocrine glands of the anal sac. PROCEDURE: Data on signalment, clinical signs, and staging were reviewed and analyzed along with treatment modality for potential association with survival time. RESULTS: Sex distribution was approximately equal (54% female, 46% male). One hundred four dogs underwent treatment consisting of surgery, radiation therapy, chemotherapy, or multimodal treatment. Median survival for treated dogs was 544 days (range, 0 to 1,873 days). Dogs treated with chemotherapy alone had significantly shorter survival (median, 212 days) than those receiving other treatments (median, 584 days). Dogs not treated with surgery had significantly shorter survival (median, 402 days) than those that underwent surgery as part of their treatment (median, 548 days). Dogs with tumors > or = 10 cm2 had significantly shorter survival (median, 292 days) than dogs with tumors < 10 cm2 (median, 584 days). Hypercalcemia was identified in 27% (n = 29) of dogs, and those dogs had significantly shorter survival (median, 256 days), compared with those that were normocalcemic (median, 584 days). Dogs with pulmonary metastasis had significantly shorter survival (median, 219 days) than dogs without evidence of pulmonary metastasis (median, 548 days). CONCLUSIONS AND CLINICAL RELEVANCE: Unlike most previous reports, this study revealed an approximately equal sex distribution, and results suggest a more favorable prognosis. 相似文献
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Outcome and complications in dogs with appendicular primary bone tumors treated with stereotactic radiotherapy and concurrent surgical stabilization 下载免费PDF全文
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Sarah E Boston DVM DVSc DACVS ACVS Founding Fellow of Surgical Oncology ACVS Founding Fellow of Oral & Maxillofacial Surgery Galina Hayes BVSc PhD DACVS DACVECC Sara A Colopy DVM PhD DACVS Katie C Kennedy DVM MS DACVS-SA ACVS Fellow of Surgical Oncology Owen T Skinner BVSc DECVS DACVS-SA ACVS Fellow of Surgical Oncology Matthew T Boylan BSc MVB Julia P Sumner BVSc MANZCVS DACVS-SA Jolle Kirpensteijn DVM PhD DACVS DECVS ACVS Founding Fellow of Surgical Oncology ACVS Founding Fellow of Minimally Invasive Surgery Frances M James MA VetMB DACVS-LA DECVS 《Veterinary surgery : VS》2020,49(5):879-883
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Kamstock DA Ehrhart EJ Getzy DM Bacon NJ Rassnick KM Moroff SD Liu SM Straw RC McKnight CA Amorim RL Bienzle D Cassali GD Cullen JM Dennis MM Esplin DG Foster RA Goldschmidt MH Gruber AD Hellmén E Howerth EW Labelle P Lenz SD Lipscomb TP Locke E McGill LD Miller MA Mouser PJ O'Toole D Pool RR Powers BE Ramos-Vara JA Roccabianca P Ross AD Sailasuta A Sarli G Scase TJ Schulman FY Shoieb AM Singh K Sledge D Smedley RC Smith KC Spangler WL Steficek B Stromberg PC Valli VE Yager J 《Veterinary pathology》2011,48(1):19-31
Neoplastic diseases are typically diagnosed by biopsy and histopathological evaluation. The pathology report is key in determining prognosis, therapeutic decisions, and overall case management and therefore requires diagnostic accuracy, completeness, and clarity. Successful management relies on collaboration between clinical veterinarians, oncologists, and pathologists. To date there has been no standardized approach or guideline for the submission, trimming, margin evaluation, or reporting of neoplastic biopsy specimens in veterinary medicine. To address this issue, a committee consisting of veterinary pathologists and oncologists was established under the auspices of the American College of Veterinary Pathologists Oncology Committee. These consensus guidelines were subsequently reviewed and endorsed by a large international group of veterinary pathologists. These recommended guidelines are not mandated but rather exist to help clinicians and veterinary pathologists optimally handle neoplastic biopsy samples. Many of these guidelines represent the collective experience of the committee members and consensus group when assessing neoplastic lesions from veterinary patients but have not met the rigors of definitive scientific study and investigation. These questions of technique, analysis, and evaluation should be put through formal scrutiny in rigorous clinical studies in the near future so that more definitive guidelines can be derived. 相似文献
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D. M. Vail G. M. Michels C. Khanna K. A. Selting C. A. London the Veterinary Cooperative Oncology Group 《Veterinary and comparative oncology》2010,8(1):28-37
Standardized assessment of response to therapy for lymphoma in dogs is lacking, making critical comparisons of treatment protocols difficult. This Veterinary Cooperative Oncology Group (VCOG) consensus document, based on the recommendations of a subcommittee of ACVIM board-certified veterinary oncologists, was unanimously adopted at the 29th Annual Conference of the Veterinary Cancer Society (VCS) by the VCOG membership. It has integrated guidance from the response assessment criteria established for lymphoma in human patients using standards available in routine veterinary oncology practices that are simple, repeatable and consistently applicable. These guidelines are intended only for use in dogs, where peripheral lymphadenopathy represents the principal component of their disease and as such do not critically assess extranodal disease (e.g., primary cutaneous, central nervous system, gastrointestinal). It is hoped these guidelines will be widely adopted and serve to facilitate the comparison of current and future treatment protocols used in the therapy of dogs. 相似文献