Crystalluria. Observations, interpretations, and misinterpretations     

C A Osborne  T D O'Brien  H K Ghobrial  L Meihak  J B Stevens 《Veterinary Clinics of North America: Small Animal Practice》1986,16(1):45-65

Crystalluria results from oversaturation of urine with crystallogenic substance. However, oversaturation may occur as a result of in vitro as well as in vivo events. The microscopic appearance of crystals only represents a tentative identification of their composition because variable conditions associated with their formation, growth, and dissolution may alter their appearance. Definitive identification is dependent on physical methods such as optical crystallography, x-ray diffraction, and electron microscopic analysis.  相似文献   

Canine distal renal tubular acidosis and urolithiasis   总被引：1，自引：0，他引：1  

D J Polzin  C A Osborne  F W Bell 《Veterinary Clinics of North America: Small Animal Practice》1986,16(2):241-250

Distal RTA is characterized by decreased distal renal tubular hydrogen ion secretion, decreased ability to acidify urine, hypercalciuria, hyperphosphaturia, hypocitraturia, and metabolic acidosis. Because of the resulting alterations in urine composition and pH, patients with distal RTA are predisposed to urolithiasis and renal calcification. Diagnosis of distal RTA is important because it is a potentially reversible disorder that, left untreated, may cause nephrocalcinosis, recurrent urolith formation, moderate to severe metabolic acidosis, and renal failure.  相似文献   

TRIALS OF SEED DRESSINGS FOR THE CONTROL OF WHEAT BULB FLY IN SCOTLAND     

P. Osborne    W. D. Gill  E. Dunn 《Plant pathology》1964,13(1):19-19

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Characteristics of Haemophilus pleuropneumoniae Isolates and Some Epidemiological Findings on Porcine Haemophilus Pleuropneumonia in Saskatchewan   总被引：4，自引：1，他引：3       下载免费PDF全文

Sebunya TN  Saunders JR  Osborne AD 《The Canadian veterinary journal. La revue veterinaire canadienne》1982,23(7):224-228

Thirty isolates of Haemophilus pleuropneumoniae from clinical and slautherhouse cases of porcine Haemophilus pleuropneumonia in Saskatchewan as well as six isolates from British Columbia and Ontario were subjected to cultural, biochemical, serological and antibiotic sensitivity tests. All strains were Gram-negative pleomorphic rods or coccobacilli which grew only in the presence of V factor and all produced porphyrin from delta-aminolaevulinic acid. Biochemically, the organism was positive for urease, O-nitrophenyl-β-D-galactopyranosidase and the fermentation of sucrose, mannitol, dextrose, lactose and xylose, but was usually negative for indole. Most strains of H. pleuropneumoniae were sensitive to chloramphenicol, furamazone, carbenicillin and ampicillin, but only about 50% were sensitive to tetracycline. Serotype 5 was more common than serotype 1 or the untyped strains among Saskatchewan isolates. In addition, serotype 3 was identified from British Columbia.

Retrospective epidemiological studies showed that Haemophilus pleuropneumonia occurred and recurred on farms in the Saskatoon and adjoining districts, serviced by the diagnostic laboratories of the Western College of Veterinary Medicine and that the disease was more common among three month old pigs during the fall-winter season.

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Determination of uric acid in canine serum and urine by high performance liquid chromatography     

Felice LJ  Dombrovskis D  Lafond E  Bartges J  Osborne CA 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1990,19(3):86-89

A reproducible high performance liquid chromatography (HPLC) method was developed for analysis of uric acid in canine serum and urine. The method consists of precipitating serum proteins with phosphotungstic acid prior to HPLC analysis. Urine is analyzed after dilution with buffer. Chromatography is performed on a reversed-phase C-18 column with UV detection at 292 nm. Sensitivity of the method will allow reproducible measurement of uric acid at concentrations of 0.05 mg/dl in serum and 0.1 mg/dl in urine. The HPLC method has been used to quantify hundreds of canine serum and urine samples. The method is superior to UV absorption or colorimetric methods because its lower limit of detection allows measurement of uric acid at concentrations found in canine serum and urine.  相似文献   

BVDV in Australian alpacas: natural infection and clinical profiles following co‐mingling with a persistently infected heifer          下载免费PDF全文

CA Evans  E Erregger  F Hemmatzadeh  PD Cockcroft 《Australian veterinary journal》2018,96(7):262-268

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Seroprevalence of antibodies to Pestivirus infections in South Australian sheep flocks          下载免费PDF全文

CA Evans  SR Lanyon  RM O’Handley  MP Reichel  PD Cockcroft 《Australian veterinary journal》2018,96(8):312-314

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Effects of sporidesmin on cultured biliary tract cells from Romney lambs that differed in their sensitivity to sporidesmin     

GC Lindsay  CA Morris  M Boucher  K Capundan 《New Zealand veterinary journal》2018,66(6):325-331

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Key Factors Affecting Reproductive Success of Thoroughbred Mares and Stallions on a Commercial Stud Farm          下载免费PDF全文

EA Lane  MLJ Bijnen  M Osborne  SJ More  ISF Henderson  P Duffy  MA Crowe 《Reproduction in domestic animals》2016,51(2):181-187

To evaluate factors contributing to fertility of thoroughbred mares, data from 3743 oestrous periods of 2385 mares were collected on a large thoroughbred farm in Ireland. Fourteen stallions (mean age 8.3 years; range 4–15 years) had bred 2385 mares (mean age 9.4 years; range 3–24 years). Maiden mares accounted for 12%, mares with a foal at foot for 64%, and barren, slipped or rested mares for 24% of the total. The mean pregnancy rate per cycle was 67.8% (68.6% in year 1 and 66.9% in year 2). Backward stepwise multivariable logistic regression analysis was utilized to develop two models to evaluate mare factors, including mare age, reproductive status, month of foaling, dystocia, month of cover, foal heat, cycle number, treatments, walk‐in status and stallion factors including stallion identity, stallion age, shuttle status, time elapsed between covers and high stallion usage on the per cycle pregnancy rate and pregnancy loss. Old age (p < 0.001) and cover within 20 days post‐partum (p < 0.003) were associated with lowered pregnancy rates. High mare age (p < 0.05) and barren, slipped or rested reproductive status (p = 0.05) increased the likelihood of pregnancy loss. Uterine inflammation or infection, if appropriately treated, did not affect fertility. Only high usage of stallions (used more than 21 times in previous week) was associated with lowered (p = 0.009) pregnancy rates. However, shuttle stallions were more likely to have increased (p = 0.035) pregnancy survival, perhaps reflecting a bias in stallion selection. In conclusion, mare age exerted the greatest influence on fertility; nonetheless, thoroughbreds can be effectively managed to achieve high reproductive performance in a commercial setting.  相似文献   

Effects of hydrochlorothiazide and diet in dogs with calcium oxalate urolithiasis   总被引：1，自引：0，他引：1  

Lulich JP  Osborne CA  Lekcharoensuk C  Kirk CA  Allen TA 《Journal of the American Veterinary Medical Association》2001,218(10):1583-1586

OBJECTIVE: To determine whether hydrochlorothiazide (HCTZ) reduces urinary calcium excretion in dogs with calcium oxalate urolithiasis. DESIGN: Original study. ANIMALS: 8 dogs with calcium oxalate urolithiasis. PROCEDURE: 4 treatment protocols were evaluated in each dog (a low calcium, low protein diet designed to prevent calcium oxalate urolith formation with and without administration of HCTZ [2 mg/kg (0.9 mg/lb) of body weight, PO, q 12 h] and a maintenance diet with higher quantities of protein and calcium with and without administration of HCTZ). At the end of each 2-week treatment period, 24-hour urine samples were collected. Blood samples were collected during the midpoint of each urine collection period. Analysis of variance was performed to evaluate the effects of HCTZ and diet on urine and serum analytes. RESULTS: Hydrochlorothiazide significantly decreased urine calcium and potassium concentration and excretion. Hydrochlorothiazide also significantly decreased serum potassium concentration. Compared with the maintenance diet, the urolith prevention diet significantly decreased urine calcium and oxalic acid concentration and excretion. Dogs consuming the urolith prevention diet had significantly lower serum concentrations of albumin and urea nitrogen. CONCLUSIONS AND CLINICAL RELEVANCE: Administration of HCTZ decreased urine calcium excretion in dogs with a history of calcium oxalate urolith formation. The greatest reduction in urine calcium concentration and excretion was achieved when dogs received HCTZ and the urolith prevention diet. Results of this study suggest that the hypocalciuric effect of HCTZ will minimize recurrence of calcium oxalate urolith formation in dogs; however, long-term controlled clinical trials are needed to confirm the safety and effectiveness of HCTZ.  相似文献