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Rausch MI Tripp MW Govoni KE Zang W Webert WJ Crooker BA Hoagland TA Zinn SA 《Journal of animal science》2002,80(1):94-100
The objective of this study was to determine the effects of level of feeding on growth, feed efficiency (gain:feed; G:F), body composition (BC), and serum concentrations of somatotropin (ST), IGF-I, and IGF-binding proteins (BP) in growing beef cattle supplemented with bovine (b) ST. In each of two consecutive years, 40 growing beef cattle were blocked by weight (average BW: yr 1 = 316 kg, yr 2 = 305 kg) and used in a 2 x 2 factorial arrangement with main effects of bST (0 or 33 microg x kg BW(-1) x d(-1)) and level of feed intake (ad libitum [AL] or 0.75 AL). Relative to uninjected cattle, treatment with bST increased ADG 9.6% (1.14 vs 1.25 kg/d; P < 0.05) and increased G:F 8.1% (12.3 vs 13.3 gain [g]:feed [kg]; P < 0.05), whereas ADG in AL animals was 39% greater than that in 0.75 AL animals (1.39 vs 1.00 kg/d; P < 0.05). There was a tendency (P = 0.10) for a bST x level of feeding interaction, such that the increase in ADG with bST was greater in AL cattle than in 0.75 AL cattle (10.6 vs 7.8%; P = 0.10). Serum concentrations of ST were greater in 0.75 AL cattle than in AL cattle (13.0 vs 8.6 ng/mL; P < 0.05) and in bST-treated cattle than in uninjected cattle (16.3 vs 5.2 ng/mL; P < 0.05). Due to a bST x level of feeding interaction (P < 0.01), the magnitude of the increase in serum ST to exogenous bST was greater (P < 0.01) in 0.75 AL cattle than in AL cattle. Relative to uninjected cattle, treatment with bST increased (P < 0.05) serum concentrations of IGF-I and IGFBP-3 and reduced (P < 0.05) concentrations of IGFBP-2. Similarly, AL cattle had greater (P < 0.05) serum concentrations of IGF-I and IGFBP-3 and reduced (P < 0.05) IGFBP-2 compared with 0.75 AL cattle. In summary, treatment with bST increased growth rate and G:F and stimulated serum IGF-I and IGFBP-3 while reducing IGFBP-2. Feeding at 0.75 ad libitum intake reduced the magnitude of response for each of these variables. Thus, limit-feeding may reduce the effect of exogenous bST on growth rate by blunting bST-induced increases in IGF-I and IGFBP-3 and bST-induced decreases in IGFBP-2. 相似文献
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A 12-week-old, clinically normal Chihuahua was referred for investigation for a continuous heart murmur. Cardiac evaluation revealed an anatomically and haemodynamically typical left-to-right shunting patent ductus arteriosus. The continuous wave Doppler measurement of peak ductal jet velocity of 5.6 m/s was suggestive of a normal pulmonary to systemic arterial pressure ratio. The dog returned 16 days later with right heart failure and severe pulmonary hypertension. Marked reduction in left-to-right shunting was demonstrated and the ductal jet velocity had decreased to 2.5 m/s. Immediate ductus ligation, oxygen therapy before and after the operation, and administration of hydralazine failed to reduce pulmonary hypertension, and the dog was euthanased. Histopathological examination of the lung showed pulmonary necrotising arteritis with acute and chronic arterial lesions. Chronic pulmonary vascular changes related to high flow have been associated with altered nitric oxide and endothelin responses. These changes may be responsible for the acute onset of pulmonary hypertension due to relatively minor vascular insults in some human and veterinary patients with left-to-right shunts. The potential for acute progression supports the recommendations for early ductus ligation and the prognostic importance of detecting pulmonary hypertension presurgically in patent ductus arteriosus patients. 相似文献
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U. Ammer G. Einsele W. Arnold O. Klee R. Agerer G. Agster U. Babel J. Behringer W. Böcking F. -H. Evers W. Fleck H. Günzl K. -F. Hofmann H. Janz J. Körner I. Kottke V. Kracht A. Krebs K. Kunzweiler W. -D. Langbein H. -U. Moosmauer S. Müller E. Nickel S. Pfeiffer R. Rausch H. Schmidt-Witte O. Schwarz R. Stegmayer 《European Journal of Forest Research》1983,102(1):282-324
Ohne Zusammenfassung
(Prof. Agerer seit 1982 am Institut für Systematische Botanik, München).
(Weilimdorf)
(zuvor t?tig bei der FVA Stuttgart, siehe oben)
(Hohenheim) 相似文献
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Ukonmaanaho L. Nieminen T. M. Rausch N. Shotyk W. 《Water, air, and soil pollution》2004,158(1):277-294
The concentrations and vertical distribution of Cu, Ni, Zn, Pb and As were studied in four different ombrotrophic peat bogs with varying heavy metal loads at Hietajärvi, Outokumpu, Harjavalta and Alkkia in Finland. At each site a peat sample (15 cm × 15 cm × 100 cm) was taken using a Titanium Wardenaar corer, and the samples were cut into 5 cm slices. Dried and milled samples were determined by X-ray fluorescence (XRF). The mean concentrations of the elements were at their highest at Harjavalta (the most polluted area), apart from Cu which had the highest value at the Cu-treated site at Alkkia. Cu concentrations were above the lowest effective limit (LOEL) on all the plots except for the background plot at Hietajärvi. The maximum Cu values were reached in the topmost 20 cm layer, indicating the effects of mining and smelting activities. The highest Zn and Ni concentrations occurred in the 0–40 cm layer. At all sites, the maximum Pb concentrations were located between 10 and 50 cm. However, the Pb concentrations were higher at Alkkia and Harjavalta than at Outokumpu and Hietajärvi, indicating anthropogenic sources of Pb at the former sites. The As concentration was also the highest in the uppermost peat layers. The mean concentrations were markedly lower in the deeper layers (40–80 cm) than in the upper layers. 相似文献
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Baumwart RD Meurs KM Atkins CE Bonagura JD DeFrancesco TC Keene BW Koplitz S Luis Fuentes V Miller MW Rausch W Spier AW 《Journal of the American Veterinary Medical Association》2005,226(7):1102-1104
OBJECTIVE: To identify clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy and echocardiographic evidence of left ventricular systolic dysfunction. DESIGN: Retrospective study. ANIMALS: 48 mature Boxers. PROCEDURE: Medical records were reviewed for information on age; sex; physical examination findings; and results of electrocardiography, 24-hour ambulatory electrocardiography, thoracic radiography, and echocardiography. RESULTS: Mean age of the dogs was 6 years (range, 1 to 11 years).Twenty (42%) dogs had a systolic murmur, and 9 (19%) had ascites. Congestive heart failure was diagnosed in 24 (50%) dogs. Seventeen (35%) dogs had a history of syncope. Mean fractional shortening was 14.4% (range, 1% to 23%). Mean left ventricular systolic and diastolic diameters were 4.5 cm (range, 3 to 6.3 cm) and 5.3 cm (range, 3.9 to 7.4 cm), respectively. Twenty-eight (58%) dogs had a sinus rhythm with ventricular premature complexes (VPCs), and 20 had supraventricular arrhythmias (15 with atrial fibrillation and 5 with sinus rhythm and atrial premature complexes). Sixteen of the dogs with supraventricular arrhythmias also had occasional VPCs. Morphology of the VPCs seen on lead II ECGs was consistent with left bundle branch block in 25 dogs, right bundle branch block in 8, and both in 11. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that Boxers with cardiomyopathy and left ventricular dysfunction frequently have arrhythmias of supraventricular or ventricular origin. Whether ventricular dysfunction was preceded by electrical disturbances could not be determined from these data, and the natural history of myocardial disease in Boxers requires further study. 相似文献
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