A comparison of the effects of carbon dioxide and medical air for abdominal insufflation on respiratory parameters in xylazine-sedated sheep undergoing laparoscopic artificial insemination     

JD Haan  BL Hay Kraus  SR Sathe 《New Zealand veterinary journal》2018,66(4):167-171

AIMS: To determine if abdominal insufflation with medical air will improve oxygenation and ventilation parameters when compared to insufflation with CO₂ in xylazine-sedated sheep undergoing laparoscopic artificial insemination (AI).

METHODS: Forty-seven sheep underwent oestrus synchronisation and were fasted for 24 hours prior to laparoscopic AI. Each animal was randomised to receive either CO₂ or medical air for abdominal insufflation. An auricular arterial catheter was placed and utilised for serial blood sampling. Respiratory rates (RR) and arterial blood samples were collected at baseline, after xylazine (0.1?mg/kg I/V) sedation, 2 minutes after Trendelenburg positioning, 5 minutes after abdominal insufflation, and 10 minutes after being returned to a standing position. Blood samples were collected in heparinised syringes, stored on ice, and analysed for arterial pH, partial pressure of arterial O₂ (PaO₂), and CO₂ (PaCO₂). The number of ewes conceiving to AI was also determined.

RESULTS: Repeated measures ANOVA demonstrated temporal effects on RR, PaO₂, PaCO₂ and arterial pH during the laparoscopic AI procedure (p<0.001), but no difference between insufflation groups (p>0.01). No sheep experienced hypercapnia (PaCO₂>50?mmHg) or acidaemia (pH<7.35). Hypoxaemia (PaO₂<70?mmHg) was diagnosed during the procedure in 14/22 (64%) ewes in the CO₂ group compared with 8/23 (35%) ewes in the medical air group (p=0.053). Overall, 15/20 (75%) ewes in the CO₂ group conceived to AI compared with 16/22 (72.7%) in the medical air group (p=0.867).

CONCLUSIONS AND CLINICAL RELEVANCE: There were no statistical or clinical differences in RR, PaO₂, PaCO₂, pH, or conception to AI when comparing the effects of CO₂ and medical air as abdominal insufflation gases. None of the sheep experienced hypercapnia or acidaemic, yet 42% (19/45) of sheep developed clinical hypoxaemia, with a higher percentage of ewes in the CO₂ group developing hypoxaemia than in the medical air group. Based on the overall analysis, medical air could be utilised as a comparable alternative for abdominal insufflation during laparoscopic AI procedures.  相似文献   

Editorial     

Ronald J Roberts  Rodney Wootten 《Journal of fish diseases》2005,28(7):381-381

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Ocular manifestations of Rocky Mountain spotted fever in dogs     

M G Davidson  E B Breitschwerdt  M P Nasisse  S M Roberts 《Journal of the American Veterinary Medical Association》1989,194(6):777-781

Dogs were examined ophthalmoscopically to determine the prevalence and type of ocular lesions associated with naturally acquired Rocky Mountain spotted fever (RMSF). In a consecutive series of 11 dogs with serologically confirmed RMSF, 9 had ocular involvement reflecting various degrees of vascular damage, including subconjunctival hemorrhage, hyphema, anterior uveitis, iris stromal hemorrhage, retinal petechiae, and focal areas of retinal edema and perivascular inflammatory cell infiltrate. The ophthalmic lesions generally were mild, and most resolved without complication after systemic administration of appropriate antibiotics. The high prevalence of ocular lesions in these dogs suggested that critical ophthalmologic evaluation is a useful diagnostic tool for the early detection and management of RMSF in dogs.  相似文献   

Penicillin-induced immune-mediated hemolytic anemia in a horse.     

R S McConnico  M C Roberts  M Tompkins 《Journal of the American Veterinary Medical Association》1992,201(9):1402-1403

A 5-year-old female American Quarter Horse was determined to have immune-mediated hemolytic anemia after detection of a positive response to a direct Coombs' test. Penicillin-induced immune-mediated hemolytic anemia was confirmed via a direct antiglobulin test, using penicillin-coated RBC. The horse was clinically improved and the anemia resolved in response to supportive care and discontinuation of penicillin treatment. Penicillin should be considered a possible cause of immune-mediated hemolytic anemia in horses.  相似文献   

Response: cystic fibrosis research     

Roberts L 《Science (New York, N.Y.)》1988,240(4859):1594

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Extinction imminent for native plants     

Roberts L 《Science (New York, N.Y.)》1988,242(4885):1508

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A hypothesis that works     

Roberts L 《Science (New York, N.Y.)》1988,240(4849):142

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Ownership of computer program     

Roberts JD 《Science (New York, N.Y.)》1983,221(4606):110-112

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Effect of nephropathogenic infectious bronchitis viruses on renal function in young male broiler chickens     

G. Afanador  J. R. Roberts 《British poultry science》1994,35(3):445-456

1. The acute effects of challenge with Australian T‐strain infectious bronchitis virus (IBV) on renal function were evaluated, following primary vaccination in 1‐d‐old male broilers.

2. Challenge with T‐strain IBV decreased body weight and induced kidney hypertrophy and kidney asymmetry.

3. Haematocrit was reduced in birds challenged with the Australian T‐strain IBV and plasma uric acid was elevated in unvaccinated birds exposed to the IBV challenge.

4. Challenge with T‐strain IBV caused significant increases in urinary water losses, accompanied by decreased urine osmolality and increased fractional excretion of sodium, calcium and potassium.

5. Vaccination at 1‐d‐old with Vic S‐strain IBV provided a limited degree of protection against an heterologous challenge with T‐strain IBV at 15 d of age.  相似文献   

Scintigraphic evaluation of tissue viability after gunshot injury in a dog.     

J Harari  G Roberts  C DeHaan 《Journal of the American Veterinary Medical Association》1992,200(10):1507-1508

Triple-phase bone scintigraphy was used to evaluate tissue viability in the forelimb of a dog after gunshot injury. This technique was reliable, noninvasive, and easily performed. It was used to complement radiography by providing functional, rather than structural, assessment of tissues on the basis of regional vascular patterns. In this dog, vascular impairment caused by trauma appeared as photopenic or "cold" spots during immediate (vascular), soft tissue and bone phases of the scintigraphic study. On the basis of gross morphologic and scintigraphic findings, forelimb amputation was performed.  相似文献