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J Grevel  W Sadée 《Science (New York, N.Y.)》1983,221(4616):1198-1201
In vitro binding studies have demonstrated the existence of multiple opiate receptor types. An additional site in the rat brain (termed the lambda site) is distinct from the established types by its selectivity for 4,5-epoxymorphinans (such as naloxone and morphine). While the lambda site displays a high affinity for naloxone in vivo and in vitro in fresh brain membrane homogenates, these sites rapidly convert in vitro to a state of low affinity. The regional distribution of the lambda site in the brain is strikingly different from that of the classic opiate receptor types.  相似文献   
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This study aims at assessing the relation between hypoalbuminemia and inhospital mortality in patients with acute stroke. In this cross-sectional study, a total of 112 consecutively admitted patients with first acute stroke in Ahvaz Jundishapur Hospital were enrolled. All patients hospitalized for 7-9 days or expired in this period of time. Admission hypoalbuminemia (serum albumin < 3.5 mg dL(-) as well as other prognostic factors were determined and compared between the two groups. One hundred and twelve patients, 74 males and 38 females with the mean age of 69.2 +/- 12.1 (66-79) years were enrolled. Twenty nine (25.9%) patients expired during the hospitalization. Totally, admission hypoal buminemia was present in 49 (43.8%) patients. 43% of the patients were Hypoalbuminemia. Frequency of patients with admission hypoalbuminemia and is chemic heart disease was significantly higher in the nonsurvivors (75.8-32.5%, p = 0.001; 34.5 vs. 16.9%, p = 0.047, respectively). The mean Glasgow Coma Scale score was significantly lower in the nonsurvivors (8.1 +/- 1.8 vs. 9.4 +/- 0.5, p = 0.003). These three parameters remained significant in multivariate analysis. Sex, age, history of hypertension, diabetes mellitus, hypertriglyceridemia, hypercholesterolemia, anemia, heart failure and smoking habit, admission atrial fibrillation, ethnicity and stroke type were comparable between the two groups. In conclusion, hypoalbuminemia is an independent predictor of inhospital mortality in patients with acute stroke.  相似文献   
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Among the models used to assess water erosion, the RUSLE model is commonly used. Policy makers can act on cover (C-factor) and conservation practice (P-factor) to reduce erosion, with less costly action on soil surface characteristics. However, the widespread use of vegetation indices such as NDVI does not allow for a proper assessment of the C-factor in drylands where stones, crusted surfaces and litter strongly influence soil protection. Two sub-factors of C, canopy cover (CC) and soil cover (SC), can be assessed from phytoecological measurements that include gravel-pebbles cover, physical mulch, annual and perennial vegetation. This paper introduces a method to calculate the C-factor from phytoecological data and, in combination with remote sensing and a geographic information system (GIS), to map it over large areas. A supervised classification, based on field phytoecological data, is applied to radiometric data from Landsat-8/OLI satellite images. Then, a C-factor value, whose SC and CC subfactors are directly derived from the phytoecological measurements, is assigned to each land cover unit. This method and RUSLE are implemented on a pilot region of 3828 km2 of the Saharan Atlas, composed of rangelands and steppe formations, and intended to become an observatory. The protective effect against erosion by gravel-pebbles (50%) is more than twice that of vegetation (23%). The C-factor derived from NDVI (0.67) is higher and more evenly distributed than that combining these two contributions (0.37 on average). Finally, priorities are proposed to decision-makers by crossing the synthetic map of erosion sensitivity and a decision matrix of management priorities.  相似文献   
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Disappearance of pyrimethanil residues on tomato plants   总被引:6,自引:0,他引:6  
The objective of this work was to estimate the disappearance of pyrimethanil, the active ingredient of Mythos 300 SC, at present, commonly used for the protection of greenhouse vegetables against diseases of fungal origin. Disappearance trends of the chemical deposits were studied on tomato plants grown in commercial greenhouses sprayed with a homogeneous 0.15% aqueous solution of the plant protection product. It was found that, on average, pyrimethanil residues on ripening fruits dropped by half and reached detection limit level in 5.7 and 13.7 days after Mythos 300 SC application, respectively. Pyrimethanil residues on tomato leaves dropped by half within 4.0 days and reached detection limit level in the first 10.5 days. Therefore, in conditions of high infection pressure, there is a need to repeat the fungicide application as early as after 3 or 4 days after previous application of Mythos 300 SC.  相似文献   
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