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1.
Chatter R Ben Othman R Rabhi S Kladi M Tarhouni S Vagias C Roussis V Guizani-Tabbane L Kharrat R 《Marine drugs》2011,9(7):1293-1306
Neorogioltriol is a tricyclic brominated diterpenoid isolated from the organic extract of the red algae Laurencia glandulifera. In the present study, the anti-inflammatory effects of neorogioltriol were evaluated both in vivo using carrageenan-induced paw edema and in vitro on lipopolysaccharide (LPS)-treated Raw264.7 macrophages. The in vivo study demonstrated that the administration of 1 mg/kg of neorogioltriol resulted in the significant reduction of carregeenan-induced rat edema. In vitro, our results show that neorogioltriol treatment decreased the luciferase activity in LPS-stimulated Raw264.7 cells, stably transfected with the NF-κB-dependent luciferase reporter. This effect on NF-κB activation is not mediated through MAPK pathways. The inhibition of NF-κB activity correlates with decreased levels of LPS-induced tumor necrosis factor-alpha (TNFα) present in neorogioltriol treated supernatant cell culture. Further analyses indicated that this product also significantly inhibited the release of nitric oxide and the expression of cyclooxygenase-2 (COX-2) in LPS-stimulated Raw264.7 cells. These latter effects could only be observed for neorogioltriol concentrations below 62.5 μM. To our knowledge, this is the first report describing a molecule derived from Laurencia glandulifera with anti-inflammatory activity both in vivo and in vitro. The effect demonstrated in vitro may be explained by the inhibition of the LPS-induced NF-κB activation and TNFα production. NO release and COX-2 expression may reinforce this effect. 相似文献
2.
Mohammad Samaun Safa 《Small-Scale Forestry》2006,5(2):207-229
The encroachment rate in forests in Bangladesh is high and increasing — accelerated by rural poverty and the demand for dwelling
space and forest products — causing environmental degradation as well as loss of forest cover and productivity. The forests
are managed by the Forest Department, although a substantial area of marginal land belongs to other semi-public agencies including
Roads and Highways and the Water Development Board. This marginal land has been left unused or underutilized. In contrast,
nongovernmental organizations have an appropriate accessibility and technology disseminating ability to utilize this land
in reducing poverty and enhancing rural livelihood, and have been highly active and successful in rehabilitating encroached
forests. NGOs have added a new dimension to forest management, which has ensured community participation and protection of
the forests, both planted and natural. This study evaluates the social forestry activities of four large NGOs, namely BRAC,
Proshika, Caritas and CARE-Bangladesh, as well as national social forestry activities. By adopting a common partnership between
public and private authority, property right conflicts have been resolved and rural livelihoods enhanced, and scope has been
created for utilizing marginal land. The NGO partnership has been effective in reducing poverty and improving livelihoods.
As an outcome of this common partnership, 33,472 km of roadside planting and 53,430 ha of reforestation activities have been
carried out during the last two decades. 相似文献
3.
Mohammad Samaun Safa 《Small-Scale Forestry》2005,4(1):117-134
Yemen is a less-developed country in the Arabian Peninsula, with only 3% arable land. An agroforestry land-use system has
been practiced traditionally by small-scale farmers, but is associated with low productivity and income. A study has been
undertaken to determine the socio-economic attributes of farmers that influence the financial performance of agroforestry
and non-agroforestry farms in the Bura’a Mountain region. A survey was conducted of 150 farmers involved in both agroforestry
and non-agroforestry. Both OLS and WLS regression were applied, and coefficients compared in terms of consistency and goodness
of fit. Incomes of farmers were found to be influenced by education, area of land, livestock holding, family size, and whether
coffee is grown, but not farmer’s age. The WLS method produced efficient and consistent results, whereas OLS regression was
affected by the heteroscedasticity. The findings of the study indicate that the farmers of the study area are in need of financial
and technical support from government to increase their income. Infrastructural development and public intervention in developing
farmers’ technical know-how could enhance production and ensure the optimum use of land as well as soil and water conservation. 相似文献
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5.
AbstractWe investigated the effect of foliar application of potassium nitrate (KNO3) and zinc sulfate (ZnSO4) on the fruit quality of pomegranate (Punica granatum L. cv. Malas-E–Torsh in Saveh). Potassium was applied as KNO3 at concentrations of 0%, 0.25%, and 0.5% and zinc was applied as ZnSO4 at concentrations of 0%, 0.5%, and 1% in a completely randomized block design. To determine the effect of the treatments on fruit quality, we measured fruit weight, peel thickness, aril diameter, phenol content of the juice, pH, total soluble solids (TSS), titratable acidity (TA), and antioxidant capacity. Foliar application of KNO3 significantly increased fruit weight, 100 aril weight, peel weight, peel thickness, TTS, and antioxidant capacity. In contrast, pH, TA, TSS/TA, and phenol content of the juice were not influenced by foliar application of KNO3. ZnSO4 significantly increased fruit weight, aril diameter, and phenol content of the juice. KNO3 1% and ZnSO4 0.5% were identified as the most appropriate treatments in improving quality and quantity of pomegranate. The fatty acid profile of the pomegranate oil was primarily composed of punicic acid, linoleic acid, oleic acid, palmitic acid, and stearic acid. 相似文献
6.
Fawzy M. Abo-Donia Safa N. Abdel-Azim Mona M. Y. Elghandour Abdelfattah Z. M. Salem Germán Buendía N. A. M. Soliman 《Tropical animal health and production》2014,46(1):221-228
This study aimed to assess impacts of fungal treatment on the nutritional value of peanut hulls (PH) or urea at the rate of 5 kg/100 g of PH. Fermented sugar beet pulp inoculated with Trichoderma viride was supplemented to PH at rates of 5.0, 10.0 and 15.0 g/100 g air dry of PH and mixed well before aerobic incubation for 21 days. Organic matter (OM) content of PH declined with increased levels of fermented sugar beet pulp inoculums, while crude protein (CP), ether extract (EE), and ash increased. Fiber contents were decreased with both treatments of fermented sugar beet pulp and urea. Total N of PH increased with urea treatment, which reduced the true protein N to total protein N ratio. In sacco degradabilities of dry matter (DM), OM, and CP with urea treatment increased compared with fungal treatment. The DM intake of peanut hulls treated with fungus (PHF) was higher (P?<?0.05) than with peanut hulls treated with urea (PHU). Digestibility of OM, CP, neutral detergent fiber, and non-fiber carbohydrate by native breed Ossimi sheep with PH were higher (P?<?0.05) than with PH or urea treated PH. The intakes, losses, and balance of N increased (P?<?0.01) with PHF versus PH feeding. Feeding PHF increased (P?<?0.01) ruminal concentrations of NH3-N, acetic acid, butyric acid, and the acetic to propionic acid ratio. Bacterial and protozoal counts increased (P?<?0.05) with feeding PHF or PHU versus PH. Overall, this fungal treatment of peanut hulls created a higher nutritive value feed for ruminants. 相似文献
7.
Mohammad Samaun Safa 《Small-Scale Forestry》2004,3(2):223-238
The sal forest is the only plainland forest in Bangladesh, and is of national economic and environmental importance. High
population and ever increasing poverty has stimulated exploitation of the forest alarmingly and brought it near extinction.
In facing this situation, the Bangladesh Forest Department implemented a participatory management approach, involving the
householders living in and around the forests, for forest maintenance and protection. This study examines the effectiveness
of practicing participatory forestry on the settlers’ livelihood in the encorached area of the sal forest. The settlers were
given degraded and encroached forest land through the program. Two major social forestry models — namely agroforestry and
woodlots — are included in the study. Participation in the resettlement increased household income, employment opportunities
and financial and non-land assets. It was found that the participatory management regime could attain the sustainability of
the forest and accelerate the standard of settlers’ livelihood, hence the program is an efficient management option towards
sustainability of the forest resources. These findings suggest that there is a role for extending the approach to rehabilitate
other degraded and encroached forest lands in Bangladesh. 相似文献
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9.
Cultivar mixture effects on disease and yield remain despite diversity in wheat height and earliness
Tiphaine Vidal Sébastien Saint-Jean Pauline Lusley Marc Leconte Safa Ben Krima Anne-Lise Boixel Wheatamix Consortium Claude de Vallavieille-Pope 《Plant pathology》2020,69(6):1148-1160
Cultivar mixtures can stabilize yield and reduce pathogen spread in plant populations. A field experiment was performed to determine (a) whether a large difference between the cultivars in the mixture (e.g., plant height or earliness) would have an impact on mixture performance, and (b) whether such differences would modify the classical rules for mixture design. Mixtures were constituted from wheat cultivars with diversity for many traits, including plant height, flowering date, disease resistance, and yield potential. The field experiment was conducted over 3 years, testing each year 72–90 mixtures of two, four, or eight cultivars, and their corresponding pure stands. Disease severity and yield of cultivar mixtures were strongly related to the mean values of the component cultivars in pure stands. Despite the considerable diversity of the mixtures tested, the classic rules (e.g., proportion of susceptible cultivars) already tested in mixtures with similar height and earliness were effective for decreasing disease severity. Agronomic heterogeneity for traits such as plant height, yield potential, or earliness of the cultivars in mixtures did not have a negative impact on disease severity and yield relative to pure stands. Increasing the number of cultivars in the mixture from two to eight had no impact on the mean disease severity and yield of the mixtures, but reduced the variability of disease severity and yield in the mixture relative to pure stands. These results suggest that it may be possible to increase within-field wheat diversity by combining more contrasting cultivars in mixtures than was previously thought. 相似文献
10.
Rauf Iqra Wajid Abdul Hussain Irshad Ather Safa Ali Muhammad Asad 《Tropical animal health and production》2019,51(6):1357-1365
The first objective of the present study was to evaluate if the antibodies induced by the live LaSota and killed Newcastle disease (sub-genotype VIIi) vaccines protect the chickens against exposure with pathogenic avian avulavirus-1 (AAvV-1) of chicken and/or pigeon origins. The second objective was to study the effect of vaccines on stressed birds (dexamethasone, aflatoxin, and heat stressed) with respect to antibody production and protection against pathogenic AAvV-1 challenge. Sixty-one-day-old Hubbard chickens were divided into six groups (gA–gF) with ten animals each. All the groups received LaSota (105 EID50, 0.1 ml per chick) on days 7 and 27 via eye drop and one intramuscular injection of a killed vaccine (sub-genotype VIIi) (107.5 EID50, 1 ml) on day 18, except the control birds received the PBS only. Moreover, group gC-DEX received dexamethasone intramuscularly at a dose rate of 1-mg/kg body weight daily; gD-AFLA had received aflatoxin as oral gavage at a dose rate of 30 ppb daily, and gE-HEAT was kept under heat stressed (38 °C) till challenged. All the groups were challenged with AAvV-1 strain of chicken origin of sub-genotype VIIi, except the group gA-pigeon was challenged with pigeon-origin strain (sub-genotype VIm). The result showed that the gA-pigeon and gB-chicken vaccinate showed 100% and 80% protection. The immunosuppressive birds produced low pre-challenge HI titer, and protection was observed at 40%, 50%, and 70% in gC-DEX, gD-AFLA, and gE-HEAT, respectively. Our findings suggest the stress factors such as aflatoxin in the feed and dexamethasone are immunosuppressive in nature and suppress the immune response and its associated protective role during infection.
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