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1.
K Seeger 《Tier?rztliche Praxis》1988,16(2):109-112
Interrelations between host, bacterium and antibiotic compound in antibiotic therapy of bacterial infections are analysed. Some methods for the evaluation of antibacterial activity of antibiotics in vitro are described and their limits, in particular of the widely used MIC tests, are demonstrated. Data from trials comparing antibiotic applications once and twice a day as well as discussions in chemotherapy, concerning the applicability of in vitro results to therapy, are used to try to find practicable guidelines for the repetition of antibiotic therapy. 相似文献
2.
SUMMARY Twenty-four of 57 calves fed a diet containing 33% cotton seed meal (CSM) died between 7 and 15 weeks of age. Initial deaths were not accompanied by premonitory signs, but after CSM withdrawal most calves developed rough coats, anorexia, weakness, ascites and subcutaneous oedema. Those that died had large volumes of serous fluid in the body cavities, hard livers of ‘nutmeg’ appearance, and pulmonary congestion. Histopathologically the livers showed periacinar necrosis in acute cases and periacinar fibrosis in chronic cases. Lungs from several calves had oedema, haemosiderosis and fibrosis in some pulmonary vessels. Atrophy of myocardial fibres was present in most cases. The concentration of free gossypol in the diet was 100 to 220 mg/kg. Ante-mortem and post-mortem findings supported a diagnosis of gossypol poisoning. The deaths continued for 4 weeks after withdrawal of CSM from the diet. 相似文献
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Accelerating invasion rate in a highly invaded estuary 总被引:4,自引:0,他引:4
Biological invasions are a major global environmental and economic problem. Analysis of the San Francisco Bay and Delta ecosystem revealed a large number of exotic species that dominate many habitats in terms of number of species, number of individuals and biomass, and a high and accelerating rate of invasion. These factors suggest that this may be the most invaded estuary in the world. Possible causes include a large number and variety of transport vectors, a depauperate native biota, and extensive natural and anthropogenic disturbance. 相似文献
5.
Seeger 《European Journal of Forest Research》1870,14(1):302-304
Ohne Zusammenfassung 相似文献
6.
Seeger 《European Journal of Forest Research》1869,13(1):328-332
Ohne Zusammenfassung 相似文献
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8.
P. Seeger U. Thorsson B. Larsson K. Rnningen 《Aquaculture (Amsterdam, Netherlands)》1977,10(4):365-371
Salmon have been sampled repeatedly from seven troughs in order to evaluate the accuracy and precision of three different sampling methods. The average length of 2-summer-old salmon was determined to the nearest half centimetre after using a large scoop net which caught somewhat more than 200 fish per sweep. To avoid bias we had to use weighted means, with the weightings proportional to the square roots of the lengths. For 1-summer-old salmon we could use a smaller scoop net and unweighted means. 相似文献
9.
Marc-Oliver Aust Sören Thiele-Bruhn Juliane Seeger Frauke Godlinski Ralph Meissner Peter Leinweber 《Water, air, and soil pollution》2010,209(1-4):143-156
Sulfonamide antibiotics can enter agricultural soils by fertilisation with contaminated manure. While only rough estimations on the extent of such applications exist, this pathway results in trace level contamination of groundwater. Therefore, we studied the transport of three sulfonamides in leachates from field lysimeters after application of a sulfonamide-contaminated liquid manure. In a 3-year period, the sulfonamides were determined in 64% to 70% of all leachate samples at concentrations between 0.08 to 56.7 µg L?1. Furthermore, sulfonamides were determined in leachates up to 23 months after application, which indicated a medium- to long-term leaching risk. Extreme dry weather conditions resulted in highest dislocated amounts of sulfonamides in two of the three treatments. Furthermore, soil management such as tillage and cropping affected the time between application and breakthrough of sulfonamides and the intra-annual distribution of sulfonamide loads in leachates. Although the total sulfonamide leaching loads were low, the concentrations exceeded the limit value of the European Commission of 0.1 µg biocide L?1 in drinking water in more than 50% of all samples. Furthermore, the medium-term mean concentration of the sulfonamides ranged from 0.08 and 4.00 µg L?1, which was above the limit value of the European Commission in 91 out of 158 samples. Therefore, sulfonamides applied to soils in liquid manure under common agricultural practice may cause environmental and health risks which call for a setting up of more long-term studies on the fate of antibiotics. 相似文献
10.