Polymorphism of BMPR1B,BMP15 and GDF9 fecundity genes in prolific Garole sheep     

Polley  Shamik  De  Sachinandan  Brahma  Biswajit  Mukherjee  Ayan  P.V.  Vinesh  Batabyal  Subhasis  Arora  Jaspreet Singh  Pan  Subhransu  Samanta  Ashis Kumar  Datta  Tirtha Kumar  Goswami  Surender Lal 《Tropical animal health and production》2010,42(5):985-993

Tropical Animal Health and Production - Mutation studies in different prolific sheep breeds have shown that the transforming growth factor beta super family ligands viz. the growth differentiation...  相似文献   

Emergent properties of reduced-genome Escherichia coli     

Pósfai G  Plunkett G  Fehér T  Frisch D  Keil GM  Umenhoffer K  Kolisnychenko V  Stahl B  Sharma SS  de Arruda M  Burland V  Harcum SW  Blattner FR 《Science (New York, N.Y.)》2006,312(5776):1044-1046

With the use of synthetic biology, we reduced the Escherichia coli K-12 genome by making planned, precise deletions. The multiple-deletion series (MDS) strains, with genome reductions up to 15%, were designed by identifying nonessential genes and sequences for elimination, including recombinogenic or mobile DNA and cryptic virulence genes, while preserving good growth profiles and protein production. Genome reduction also led to unanticipated beneficial properties: high electroporation efficiency and accurate propagation of recombinant genes and plasmids that were unstable in other strains. Eradication of stress-induced transposition evidently stabilized the MDS genomes and provided some of the new properties.  相似文献