Clinical presentation and management of suspected ribavirin toxicosis in a dog     

Kimberly Bridges  Nicole Beckel  Claire Sharp  Laura Stern 《The Canadian veterinary journal. La revue veterinaire canadienne》2016,57(5):511-513

A 5-month-old pit bull terrier was presented for evaluation of progressive lethargy, vomiting, diarrhea, and anorexia 45 hours after ingestion of 625 mg/kg body weight (BW) (9000 mg) of the antiviral medication, ribavirin. Abnormalities that were detected included dehydration, tachycardia, elevated liver enzymes, and prolonged prothrombin time. The dog was discharged after 5 days of aggressive supportive care consisting of intravenous fluids, antiemetics, gastroprotectants, hepatoprotectants, dextrose supplementation, and vitamin B/K1 supplementation.  相似文献   

Diagnostic Value of Right Pulmonary Artery Distensibility Index in Dogs with Pulmonary Hypertension: Comparison with Doppler Echocardiographic Estimates of Pulmonary Arterial Pressure          下载免费PDF全文

L.C. Visser  M.K. Im  L.R. Johnson  J.A. Stern 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(2):543-552

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Atrial Fibrillation in Eight New World Camelids          下载免费PDF全文

R. Bozorgmanesh  K.G. Magdesian  K.E. Estell  J.A. Stern  E.A. Swain  L.G. Griffiths 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(1):335-338

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Successful multimodal treatment of extreme hypertriglyceridemia in a juvenile diabetic dog     

Aria L. Guarino DVM  DACVIM  Laura A. Cagle DVM  PhD  DACVECC  Caryn M. Ehrhardt DVM  Sarah S. K. Beatty DVM  DACVP  Jere K. Stern DVM  Chen Gilor DVM  DACVIM  Andrew J. Specht DVM  DACVIM  Leo A. Londoño DVM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(2):247-256

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Circulating neutrophil extracellular traps in cats with hypertrophic cardiomyopathy and cardiogenic arterial thromboembolism     

Ronald H. L. Li  Arianne Fabella  Nghi Nguyen  Joanna L. Kaplan  Eric Ontiveros  Joshua A. Stern 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(2):490-502

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The importance of Campylobacter jejuni to the meat industry: a review     

A W Kotula  N J Stern 《Journal of animal science》1984,58(6):1561-1566

Campylobacter jejuni is a microorganism that only recently has been implicated in gastroenteritis in humans. As appropriate methods used for detection of the bacterium have been developed, the rates of illness caused by the pathogen were found to approach or surpass those attributed to Salmonella. Substantial evidence has been gathered to document that the route for human infection is through the ingestion of adulterated food and drink. Some slaughter animals harbor this potential pathogen among the intestinal flora and, consequently, transfer of the organism to carcasses and to the resulting meat products does occur. The most frequently implicated meat is poultry, with an incidence of recovery of C. jejuni from the store-bought poultry meat reported to be at least 50%. Red meat from slaughter animals have also yielded this bacterium from carcasses, but at lower incidence levels. Foodborne disease has been associated most frequently with the ingestion of raw milk, but poultry, hamburger, and other foods have all been implicated as potential sources. However, cause and effect relating the presence of C. jejuni in meat and human gastroenteritis has not been demonstrated. Additional research is needed to determine whether C. jejuni isolated from meat causes gastroenteritis and whether all strains of the organism are virulent. Recognition of C. jejuni as a potential meatborne pathogen by the meat industry is necessary, and appropriate sanitary practices to prevent passage of the organism through meat products should be implemented.  相似文献   

Identification of a new source of Campylobacter contamination in poultry: transmission from breeder hens to broiler chickens     

Cox NA  Stern NJ  Hiett KL  Berrang ME 《Avian diseases》2002,46(3):535-541

Campylobacter jejuni, a foodborne pathogen closely associated with market poultry, is considered to be the most frequent agent of human gastroenteritis in the United States. The pathways involved in the contamination of poultry flocks, vertical transmission and/or horizontal transmission, are unclear. In this study, Campylobacter isolates from two independent commercial broiler breeder flocks, as well as from their respective progeny, were characterized and compared by PstI ribotype analysis and by DNA sequence analysis of the short variable region (SVR) of the flaA gene (flaA SVR). Campylobacter isolates originating from one set of breeder hens and the feces from their respective progeny demonstrated identical ribotype patterns as well as identical flaA SVR DNA sequences, thereby suggesting that these isolates were clonal in origin. Ribotype analysis of Campylobacter isolates from the second set of breeder hens and processed carcasses from their offspring resulted in two patterns. Sequence analysis placed these isolates into two closely related groups and one distant group, similar to the ribotype analysis. These results demonstrate that Campylobacter isolates from commercial broiler breeder flocks and from the respective broiler progeny may be of clonal origin and that breeder hens can serve as a source for Campylobacter contamination in poultry flocks.  相似文献   

Effect of supplemental niacin or niacinamide and soybean source on ruminal bacterial fermentation in continuous culture     

S M Hannah  M D Stern 《Journal of animal science》1985,61(5):1253-1263

Effects of niacin or niacinamide in diets containing either soybean meal, raw whole soybeans or whole soybeans extruded at 132 and 149 C on ruminal bacterial fermentation were examined with a dual-flow continuous culture system. In Exp. 1, soybean sources each provided 50% of total crude protein in diets comprised of 52% concentrate mix, 36% corn silage and 12% alfalfa hay (dry-matter basis). Each diet was supplemented with 0 or 100 mg/kg niacin. Niacin supplementation increased (P less than .05) total nonstructural carbohydrate digestibility and lowered (P less than .05) butyrate concentration. There was also an increase (P less than .10) in amino acid effluent flow from 8,413.3 to 8,665.3 mg/d with addition of niacin to the diet. In Exp. 2, diets were supplemented with 0 or 100 mg/kg of niacin or niacinamide. The total mixed diet was comprised of 60% concentrate mix, 20% corn silage and 20% alfalfa hay (dry matter basis). Acid detergent fiber and cellulose digestibilities and total amino acid effluent flow were higher (P less than .10) with niacinamide supplementation. Niacin or niacinamide had no effect on dry matter and organic matter digestibilities, ammonia-N, total VFA concentration or crude protein degradation. Contrary to results found in other studies, niacin or niacinamide supplementation had no effect on bacterial protein synthesis.  相似文献   

Renumbering the S-RNase alleles of European pears (Pyrus communis L.) and cloning the S109 RNase allele     

Martin Goldway  Takashi Takasaki-Yasuda  Javier Sanzol  Mariana Mota  Annat Zisovich  Raphael A. Stern  Silviero Sansavini 《Scientia Horticulturae》2009

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An "Invisible" Chromosome     

Kodani M  Stern C 《Science (New York, N.Y.)》1946,104(2713):620-621

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