Radiographic interpretation of normal skeletal variations and pseudolesions in the equine foot.     

J L Becht  R D Park  S L Kraft  P F Steyn  R H Wrigley 《Veterinary Clinics of North America: Equine Practice》2001,17(1):1-18

Effective radiographic interpretation requires a veterinarian who is knowledgeable of equine limb anatomy and the various principles that affect the resulting image. The normal and its variations must be recognized and understood before the abnormal can be confidently identified as pathologic. Proper patient positioning and sound radiographic technique are mandatory if reliable diagnostic radiographs are to be produced. This review emphasizes equine foot radiographic variations of normal and pseudolesions that occur with commonly used radiographic views performed in equine practice.  相似文献   

Lymphosarcoma with disseminated skeletal involvement in a pup     

K S Rogers  E B Janovitz  S K Fooshee  P F Steyn  K E Frankum 《Journal of the American Veterinary Medical Association》1989,195(9):1242-1244

Lymphoblastic lymphosarcoma with disseminated skeletal involvement was diagnosed in a 15-week-old Golden Retriever. The skeletal disease was characterized by diffuse, irregular areas of radiolucency most evident in the diaphyseal portion of long bones and was associated with gait abnormalities and signs of pain. Necropsy also revealed involvement of the spleen, liver, kidneys, and mesenteric lymph nodes.  相似文献   

THE NON-CARDIAC DISTRIBUTION OF ^99mTC-METHOXY-ISOBUTYL-ISONITRILE (SESTAMIBI) IN NORMAL BEAGLES     

Phillip F.  Steyn  BVSc  MRCVS  MS  Gregory  Ogilvie  DVM 《Veterinary radiology & ultrasound》1995,36(2):160-163

Technetium-99m methoxy-isobutyl-isonitrile (sestamibi) is a radiophartnaceutical used for the evaluation of myocardial perfusion. Increased uptake of sestamibi has also been documented in tumors. The objective of this study was to document the extracardiac biodistribution of ^99mTc sestamibi in the normal dog. Nine normal beagles were given 0.35 mCi/kg ^99mTc sestamibi intravenously, and 60 second images were made of the entire body at 1 hour post injection. A defined distribution pattern was recognized, with good visualization of the heart, liver, gallbladder, small intestine, kidneys, urinary bladder, popliteal lymph nodes, parotid salivary glands and zygomatic salivary glands. Splenic uptake was not seen.
Target to background ratios were calculated for all the regions listed, using background regions-of-interest with the smallest coefficient of variance for the denominator. The mean, range and standard deviation of these ratios are given.  相似文献   

Salmonella isolated from feeds and feed ingredients during the period 1982-1988: animal and public health implications     

A M Durand  W H Giesecke  M L Barnard  M L van der Walt  H C Steyn 《The Onderstepoort journal of veterinary research》1990,57(3):175-181

The prevalence of Salmonella in southern Africa in farm feeds and by-products of animal origin during 1982-1988 was determined. Salmonella occurred in 5.18% of the farm feed samples and in 9.54% of the by-product samples. Different serovars were isolated, some only once. The findings underestimate the true prevalence of Salmonella in farm feeds and by-products, and is representative of only the most severely contaminated products. The epidemiology of salmonellosis is discussed with special reference to the importance of multiple resistance to antibiotics, the increase in the number of cases of salmonellosis worldwide and "Salmonella free" feeds and foods. More detailed research on the role of farm feeds in the epidemiology of salmonellosis is required. Efforts should be made to increase awareness of the problem, to improve quality management at farm feed production plants and to develop efficient systems to monitor the hygienic safety of feeds and foods.  相似文献   

Relative bioavailability of rafoxanide following intraruminal and intra-abomasal administration in sheep     

Swan GE  Koeleman HA  Steyn HS  Mülders MS 《Journal of the South African Veterinary Association》1999,70(2):71-74

The bioavailability of rafoxanide was compared after intraruminal and intra-abomasal administration in healthy adult sheep (n = 6) in a single dose, 2 parallel group study at 7.5 mg/kg. Rafoxanide concentrations in plasma were measured by means of HPLC analysis. Primary pharmacokinetic parameters for bioavailability and disposition of rafoxanide in plasma for both routes of administration were determined by non-compartmental and non-linear, 1-compartmental pharmacokinetic analysis, respectively. Significantly (P < or = 0.05) higher peak plasma concentrations (c(max)) of rafoxanide and a more rapid rate of absorption (c. 3.5 times) was observed in sheep after intra-abomasal (i-a) administration compared to intraruminal (i.r.) administration. A significantly (P < or = 0.05) longer lag period (t(lag)) before absorption (6.8 +/- 2.9 h) occurred after i.r. than after i-a treatment (1.9 +/- 0.6 h). There was no significant difference (P > 0.05) in AUC, MRT and in the rates of elimination (k10-HL and t(1/2beta)) between the i.r. and i-a routes of administration. The results of the study demonstrated the important influence of the rumino-reticulum on absorption of rafoxanide in sheep.  相似文献   

Use of positive contrast rhinography and intranasal sinography for diagnosis of a nasofacial sinus tract in a dog     

Cruz-Arámbulo Rde J  Monnet E  Steyn PF  Shelly S  Hays C 《Journal of the American Veterinary Medical Association》2003,222(11):1569-72, 1547

Twelve days after a dog fight, a 2-year-old sexually intact female Bulldog was evaluated because of subcutaneous emphysema of increasing severity throughout the dogs body. Thoracic radiography revealed severe pneumomediastinum from which free air had extended into the retroperitoneal space, resulting in pneumoperitoneum. Tracheoscopic examination did not reveal a discontinuity of the trachea, pharynx, or larynx. A breach between the nasal cavity and subcutaneous tissues of the nasal region was suspected. Further diagnostic investigations included positive contrast rhinography and intranasal sinography. Via an angiographic catheter inserted into the left naris, positive contrast intranasal sinography revealed a sinus tract extending between the left nasal cavity and the subcutaneous tissue of the dorsal aspect of the nasal planum. Resolution of subcutaneous emphysema, pneumomediastinum, and pneumoretroperitoneum began 1 day after surgical closure of the intranasal opening of the sinus tract. To the authors' knowledge, this radiographic technique has not been reported.  相似文献   

Regression of hypertrophic osteopathy in a filly following successful management of an intrathoracic abscess     

M K Chaffin  W W Ruoff  D G Schmitz  G K Carter  E L Morris  P Steyn 《Equine veterinary journal》1990,22(1):62-65

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A molecular epidemiologic investigation of Salmonella from a meat source to the feces of captive cheetah (Acinonyx jubatus).     

Estelle H Venter  Moritz van Vuuren  Johann Carstens  Martha L van der Walt  Badenhorst Nieuwoudt  Helena Steyn  Nick P J Kriek 《Journal of zoo and wildlife medicine》2003,34(1):76-81

Low cheetah (Acinonyx jubatus) birth rates were observed for a long time in a captive breeding facility in which Salmonella, which was possibly present in contaminated beef, was isolated from still-born lion (Panthera leo) cubs. Salmonella, including 14 isolates of Salmonella serovar typhimurium and 19 isolates of Salmonella serovar muenchen, was subsequently isolated 47 times from 378 meat samples at the facility during a 13-mo period. Salmonella, including 26 isolates of S. serovar typhimurium, 10 of S. serovar muenchen, and 11 other serovars, also was isolated 54 times from 119 fecal samples. Only three plasmid profiles were identified in 59 S. typhimurium isolates from both meat and fecal samples. Although random-amplified polymorphic DNA fingerprinting using different primers in the polymerase chain reaction was able to distinguish between S. typhimurium and S. muenchen and to demonstrate similar chromosomal DNA fingerprints in some of the isolates from meat and feces, the results were not consistent enough to prove that the Salmonella in the feces originated from contaminated meat. However, the predominance of only two serovars in the meat fed to carnivores and in the feces of these animals suggests that the meat was the source of the Salmonella organisms in the feces.  相似文献   

The 18th International Congress of Nutrition takes place on African soil     

Steyn NP 《Public health nutrition》2005,8(5):441-443

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Isolation and purification of moniliformin   总被引：4，自引：0，他引：4  

M Steyn  P G Thiel  G C van Schalkwyk 《Journal of the Association of Official Analytical Chemists》1978,61(3):578-580

A bulk purification procedure is described for moniliformin, a mycotoxin produced by Fusarium moniliforme. The method involves methanol extraction of suitably molded maize, aqueous extraction of the methanol-free residue, ion exchange chromatography with a NaCl concentration gradient, desalination, and crystallization. A pKa value of 1.70 as well as molar absorptivities of 19100 (lambda (H2O) max 229 nm), 5600 (lambda (H2O) max 260 nm), and 4700 (lambda (MeOH) max 260 nm) L/mole/cm are reported for moniliformin.  相似文献