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1.
Urban dwellers experience conflicting thoughts and feelings about urban woodlands; valued for their natural qualities, the relief they provide from the stress of modern urban living and the opportunities they afford for children's play and exploration. At the same time the seclusion inherent in this type of urban greenspace seems fraught with risk from crime, vandalism and abuse. Whilst many of these characteristics are well-researched, less is known about the differing perceptions of particular social groups. This study aimed to explore the ways in which age affects urban dwellers’ aspirations, values and fears concerning the woods, and woodland accessibility, focusing on the views of elderly people (aged over 65). This pilot study was based in Norfolk Heritage Park, an urban park containing a variety of woodland settings located in Sheffield, UK. The questionnaire survey (participantsn=97) revealed that although walking is the most popular leisure activity, most respondents did not visit urban parks as often as they would like, regardless of age. Whilst many of the meanings associated with urban woodland (“relaxation”, “peacefulness”, “seasonal change”, “scenery” and “education”) were shared amongst age groups, it seemed that the elderly respondents particularly valued the woods for their links with the past, and opportunities for immersion in the natural world. Some respondents from all age groups had fears about their personal security in the woodland, and the concerns of the elderly were heightened by their perceived frailty, reduced mobility and sense of vulnerability; this age group had a corresponding need for particular measures to alleviate these problems. The study provides preliminary evidence for the idea that adults of different ages have differing perceptions and requirements in relation to urban woodlands. Due to the small sample size and other methodological issues, further research is needed to confirm and develop the findings. 相似文献
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Jorunn Skjermo Trond R. Størseth Karina Hansen Gunvor Øie 《Aquaculture (Amsterdam, Netherlands)》2006,261(3):1088-1101
Stimulation of the non-specific defence enhances the disease resistance and growth, and has good potentials as a measure for increased microbial control in juvenile production of marine fish and shellfish. So far, the most commonly used immunostimulants are β-(1 → 3, 1 → 6)-glucans, and in this study the stimulatory potential of a β-(1 → 3, 1 → 6)-glucan of marine origin, the storage polysaccharide from the marine diatom Chaetoceros mülleri, was examined. The glucan (chrysolaminaran) was extracted from cultures of C. mülleri, and used as a dietary supplement in two first feeding experiments with larvae of Atlantic cod Gadus morhua L. In one experiment the microalgal glucan was compared to the commercial yeast-glucan product MacroGard®, and in the other to an alginate with a high content of mannuronic acid (High-M alginate) isolated from Durvillaea antarctica. The stimulants were given via rotifers, and weaning to formulated feed was initiated at day 17 or 18 after hatching. The survival ± SEM at day 27 after hatching was 24.5 ± 2.0%, 14.8 ± 4.5% and 13.1 ± 1.4% for the groups fed C. mülleri-glucan, yeast glucan and for the control, respectively, in the first experiment. The group fed C. mülleri-glucan group had higher survival compared to the control (P < 0.05) group, whereas the yeast glucan had no positive effect on the survival (p > 0.05). The dry weights of the groups at day 27 were low, with 203.2 ± 52.2, 165.2 ± 43.4 and 198.5 ± 58.1 μg per larva for the C. mülleri-glucan, yeast glucan and control groups, respectively. In the second experiment the survival in the period of feeding formulated feed (days 18-30) were 44.6 ± 4.3%, 44.7 ± 1.3%, and 33.8 ± 4.1% survival for the C. mülleri-glucan, High-M alginate and control group, respectively. The cod larvae fed C. mülleri-glucan reached an average weight of 531.6 ± 17.2 μg at day 30, which was significantly higher (p < 0.05) than the control group that had an average of 473.6 ± 3.5 μg. The larvae fed High-M alginate had an average weight of 470.3 ± 31.6 μg per larva at day 30, and not significantly different from the control (p > 0.05). The early weaning to formulated diet had detrimental effect on the growth of the larvae. In both experiments the C. mülleri-glucan group was the only group showing a positive growth rate in the period of weaning to dry feed. The microbial conditions in larval gut and water were monitored with respect to total colony forming units on Marine agar, and Vibrio- and Pseudomonas-like species on selective agars (TCBS and marine Pseudomonas Agar with CFC-supplement). The larvae were rapidly colonised after hatching, but no or weak effects of the stimulants were observed on the colonisation rates or the composition. The total CFU varied from 101 to 102 CFU per μg larva after initiation of the first feeding. The percentages of Pseudomonas-like bacteria increased throughout the period, whereas the levels of Vibrio-like bacteria were low and stable. The chrysolaminaran from the diatom C. mülleri was shown to be a promising candidate for use as an immunostimulatory feed additive, and which should be further explored. 相似文献
4.
S K Heimbecher K V Jorgensen R L Price 《Journal of the Association of Official Analytical Chemists》1988,71(2):285-287
Spray-dried skim milk, naturally contaminated with aflatoxin M1, was added to either raw or pasteurized whole milk to a final concentration of 1.1 microgram aflatoxin M1/L milk. Formalin (37% w/w) was added to the milk solutions to final concentrations of 0, 0.025, 0.05, and 0.1% formaldehyde. Samples were stored in the dark at 21 degrees C in plastic and glass containers and were analyzed for aflatoxin M1 at 0, 1, 2, 3, and 4 weeks. This experiment was repeated using only raw milk and glass containers. Aflatoxin M1 analyses were done at 0, 1, and 2 weeks. Aflatoxin M1 losses increased over time and with increased formaldehyde concentration. With both experiments, aflatoxin M1, levels after 2 weeks were less than 0.05 micrograms/L in samples containing 0.1% formaldehyde. 相似文献
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Jorgensen WL 《Science (New York, N.Y.)》2004,303(5665):1813-1818
An overview is given on the diverse uses of computational chemistry in drug discovery. Particular emphasis is placed on virtual screening, de novo design, evaluation of drug-likeness, and advanced methods for determining protein-ligand binding. 相似文献
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Jorgensen RA 《Science (New York, N.Y.)》2011,333(6046):1103-1104
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Alkaline hydrolyzates of RNA made in vivo by Escherichia coli contain ribonucleoside-3'-monophosphate-5'-triphosphates. These probably arise by hydrolysis of the initial nucleoside triphosphate from the 5' terminus of the nascent RNA chains. Logarithmically growing cultures, labeled for 45 seconds with (32)P-labeled phosphate, yield about 2000 molecules of labeled tetraphosphate per cell, this yield increasing only slightly with continued labeling. Only the tetraphosphates of adenosine and guanosine have been found in Escherichia coli, and these two are present in approximately equal amounts. 相似文献
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Running exercise in pigs results in an elevation of lactic acid in blood. This elevation in blood lactate does not occur in physically conditioned pigs. Activities of succinic dehydrogenase, fructose-l,6-diphosphate aldolase, lactate dehydrogenase and creatine Phosphokinase as well as the myoglobin content were determined in m. gastrocnemius from 6 ergometer-trained and 4 untrained pigs. The succinic dehydrogenase and myoglobin contents were significantly higher (P<0.01) in trained animals, whereas no changes were noted in the aldolase and creatine Phosphokinase contents. The lactate dehydrogenase showed somewhat reduced levels in the trained pigs. This was accompanied by an increased H/M subunit ratio. The results provide evidence for an increase in the maximal aerobic metabolism in trained pigs and that trained pigs to a higher extent can rely on an aerobic energy metabolism during running exercise. 相似文献