Breed, age and gender distribution of dogs with chronic hepatitis in the United Kingdom     

Bexfield NH  Buxton RJ  Vicek TJ  Day MJ  Bailey SM  Haugland SP  Morrison LR  Else RW  Constantino-Casas F  Watson PJ 《Veterinary journal (London, England : 1997)》2012,193(1):124-128

Standardised histological criteria are now available for the diagnosis of canine chronic hepatitis (CH). CH is common in dogs, but no studies have reported breed, age and gender distributions in the United Kingdom (UK). The objective of this study was to determine which breeds had an increased risk for developing CH in the UK and to report the age and gender distribution for those breeds. The databases of six veterinary histopathology laboratories were searched for cases with a histological diagnosis of CH according to standardised criteria. The breed, age and gender of dogs was recorded and compared to a control population to calculate the odds ratio and 95% confidence intervals for developing CH. A total of 551 cases of CH were identified, consisting of 61 breeds. Nineteen breeds were represented by five or more cases. Breeds with an increased risk for developing CH included the American cocker spaniel, Cairn terrier, Dalmatian, Dobermann pinscher, English cocker spaniel, English springer spaniel, Great Dane, Labrador retriever and Samoyed. The median age at diagnosis for all breeds with CH was 8 years (range 7 months to 16 years). Dalmatians, Dobermann pinschers and English springer spaniels with CH were significantly younger than Cairn terriers, English cocker spaniels and Labrador retrievers with CH. Females were over-represented when all cases were examined together. In conclusion, several breeds in the UK have an increased risk of CH, some of which have not been previously reported.  相似文献   

CHRONIC RENAL FAILURE ASSOCIATED WITH NEPHROLITHIASIS, URETEROLITHIASIS, AND RENAL DYSPLASIA IN A 2-YEAR-OLD QUARTER HORSE GELDING     

Anne A.  Wooldridge  DVM  Thomas L.  Seahorn  DVM  MS  Jamie  Williams  MS  DVM  H. Wayne  Taylor  DVM  Ph.D.  Julian L.  Oliver  DVM  Ph.D.  Dae  Young  Kim  DVM  Thomas J.  Vicek  DVM 《Veterinary radiology & ultrasound》1999,40(4):361-364

A 2-year-old quarter horse gelding presented for evaluation of polyuria and polydipsia. Azotemia was detected on serum chemistry profile. Small, misshapen, hyperechoic kidneys with decreased corticomedullary demarcation, hydronephrosis, and a right nephrolith were noted ultrasonographically. The diagnosis of end-stage kidney disease and dysplasia was made histopathologically using ultrasound-guided biopsy. Two ureteroliths were found in the right ureter via cystoscopy, and a nephrolith was seen in the right kidney at necropsy. Clinical, ultrasonographic, and pathologic features of equine urolithiasis and renal dysplasia are discussed.  相似文献