Comparison of N-terminal pro-atrial natriuretic peptide and three cardiac biomarkers for discriminatory ability of clinical stage in dogs with myxomatous mitral valve disease     

Mizuki OGAWA  Yasutomo HORI  Nobuyuki KANNO  Naoki IWASA  Takeshi TOYOFUKU  Noriko ISAYAMA  Akane YOSHIKAWA  Ryota AKABANE  Atsushi SAKATANI  Hirosumi MIYAKAWA  Huai-Hsun HSU  Yuichi MIYAGAWA  Naoyuki TAKEMURA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(4):705

Plasma N-terminal pro-atrial natriuretic peptide (NT-proANP) concentration increases with progression of myxomatous mitral valve disease (MMVD) in dogs. This multicentre, prospective study compared plasma NT-proANP, N-terminal pro-brain natriuretic peptide (NT-proBNP), ANP, and cardiac troponin I (cTnI) concentrations in dogs with MMVD for their characteristics and discriminatory ability to detect cardiac dilatation and congestive heart failure (CHF). Thirty-six healthy dogs and 69 dogs with MMVD were included. Clinical variables were obtained via physical examination, thoracic radiography, and echocardiography. The discriminatory ability of each cardiac biomarker (CB) to determine the presence or absence of cardiac dilatation (event 1) and CHF (event 2) was evaluated using the receiver operating characteristic curves. Plasma NT-proANP, NT-proBNP, and ANP concentrations showed a significant association with the left atrium/aorta ratio (P<0.01). The area under the curve of plasma NT-proANP and NT-proBNP concentrations were 0.72 and 0.75, respectively in event1 and 0.72 and 0.76, respectively in event2. Plasma NT-proANP and NT-proBNP concentrations showed sensitivity 80.0 and 80.0%; specificity 67.6 and 64.7% in event1 (cutoff value; 8,497.81 pg/ml and 1,453.00 pmol/l, respectively) and sensitivity 85.7 and 81.0%; specificity 60.4 and 64.6% in event2 (cutoff value; 8,684.33 pg/ml and 1,772.00 pmol/l, respectively). In dogs with MMVD, plasma NT-proANP, NT-proBNP, and ANP concentrations increase with left atrial enlargement. Particularly, plasma NT-proANP and NT-proBNP concentrations appeared to be equally useful in the discriminatory ability to detect cardiac dilatation and CHF.  相似文献   

Soil and phosphorus redistribution along a steep tea plantation in the Feitsui reservoir catchment of northern Taiwan     

Franz ZEHETNER  Narasimham L. VEMURI  Chih-An HUH  Shuh-Ji KAO  Shih-Chieh HSU  Jr-Chuan HUANG  Zueng-Sang CHEN 《Soil Science and Plant Nutrition》2008,54(4):618-626

Feitsui reservoir, the major water supply of Taipei city, has shown declining water quality in recent years. The reservoir is located in an area famous for tea cultivation, and the question arises as to whether the hillside tea plantations have contributed to increased sediment and nutrient discharge into the reservoir. In this study, soil and phosphorus redistribution were examined along a steep tea plantation in the reservoir's catchment and the provenance of reservoir sediment was assessed. Fallout radionuclides were used as soil erosion/deposition tracers and as markers of sediment sources. Continuous fertilizer application has raised (inorganic) phosphorus levels in the studied tea plantation. The plantation's narrow bench terraces trap eroded material and slow down soil and nutrient translocation. Nevertheless, eroded soil and phosphorus have accumulated on a vegetated toeslope below the tea plantation. The reservoir sediment contained significant amounts of inorganic phosphorus and cesium-137, and application of a mixing model resulted in a surface soil contribution of approximately 30%. This points towards tea plantations as possible sediment and pollutant sources and underlines the necessity of soil conservation strategies, such as the maintenance of vegetated riparian buffer zones. However, other sources, such as landslide debris and urban wastewaters, cannot be entirely ruled out. Further research is needed to better characterize the catchment's soils and sediments and to improve sediment fingerprinting efforts. Potential point and non-point pollution sources need to be examined in detail to better understand how phosphorus enters the reservoir.  相似文献   

智能化海量空间信息分析与地图制图软件包IMAT设计及构建     

张维理 《中国农业科学》2014,47(16):3250-3263

【目的】在农业与环境研究领域,受研究条件和手段限制,多数研究实际上只能集中于点过程、局部地区或某一时段问题,只能关注某些特定主题相关现象和机制。由此产生大量分散数据。通过坐标关联可以对原先在各自独立研究中获取的不同类型数据与证据进行关联,这种连接可能赋予原先所认知的过程以新的涵义。海量空间数据分析方法能够从多渠道、多角度获得对事物的认知,并能够利用新的数据与证据不断修订假设。大数据分析的主要难点是海量空间信息不仅体量大,还要根据数据异质类型进行差异化抽提、整合和表达,难以采用现有主流软件工具,针对这一问题,本研究旨在创建一个能够以自动化和人机交互方式对异源、异质海量空间信息进行抽提、整合与大尺度、大比例尺专题图表达的专用工具--智能制图工具（IMAT）。【方法】采用海量空间信息分析方法中的流程设计与软件设计原则构建IMAT。总设计由系统体系架构设计、系统数据支撑平台设计、模块与组件模型设计3部分组成。程序采用C#为编程语言,以NET Framework 4 Extended为软件开发环境,同时调用制图软件包ArcGIS、数据库软件包Access与界面制作软件包DotNet Bar控件。【结果】IMAT含38个独立功能模块,覆盖了对农业与环境领域产生的海量空间信息进行抽提与制图表达所需主要功能,各模块既可独立进行某项特定数据分析与处理,例如,海量信息调用、存贮、空间要素统计、分类码审核、赋码、要素筛选、数据整合、制图表达等,也可通过多模块组合,完成一项比较复杂的数据抽提与表达任务,弥补了国内外主流数据库软件包与专业制图软件包与在处理海量空间信息方面的功能缺失。IMAT数据分析对象为海量空间数据库。在进行数据分析时,IMAT能够根据研究目标设定对各异源、异质、异构库进行信息抽提的规则,并以自动化、批量化方式完成海量空间信息的逻辑结构与存储结构整合;在进行制图表达时,IMAT能在全图设定分幅图差异化要素抽提规则,并以智能化、自动化、人机交互方式完成由多图幅组成的大比例尺专题图全图的视图表达。【结论】在对农业与环境主题相关海量空间信息进行分析时,IMAT既适用于土壤类型、土壤质地等以多等级分类系统表示的专题要素,也适用于土壤养分含量、土壤污染物含量、面源污染排放指数等以量化分级指标表达的专题要素;既可用于对多专题要素与图层的综合性信息抽提与复合性制图表达,还能用于进行不同比例尺、不同分幅类型的可视化地图制图。IMAT设计中采用组建化模块与模型设计构筑系统体系架构,提高了设计与研制效率;利用函数化的海量空间数据集四元表达式作为IMAT系统中各空间数据库接口文件,使得IMAT各模块均能够接受和处理处于数据整合与表达进程不同阶段的异质、异构海量空间信息,从而实现了各功能模块的可装配性,分析人员能根据数据抽提、整合和表达目标选择并灵活组合适宜的功能模块。  相似文献   

粉红色索尔邦百合的组培快繁技术研究     

张伟丽  金欣庆 《北方园艺》2007,(4):212-214

研究了以索尔邦百合(Lilium Sorbonne)的鳞片叶为外植体的组培和植株离体再生技术,培养基采用MS基本培养基,附加不同的激素组合.分别获得诱导的愈伤组织、芽及根,并遴选出最佳激素组合,以确立索尔邦百合组织培养再生系统.试验结果表明适合的诱导培养基是MS BA0.5mg/L NAA 0.2mg/L;继代培养基为MS 2,4-D 1.0mg/L和MS BA 0.5mg/L NAA0.2mg/L;生根培养基是1/2MS IBA0.2mg/L和1/2MS NAA0.2mg/L.该方法最大增殖倍数达到5.74.  相似文献   

Effect of different sources of dietary fibre on growth performance,intestinal morphology and caecal carbohydrases of domestic geese     

B. YU  C.-C. TSAI  J.-C. HSU  P.W.-S. CHIOU 《British poultry science》1998,39(4):560-567

1. The aim of this study was to examine the effects of dietary fibre sources on growth and on the development of the gastro-intestinal tract in growing geese. 2. Six-week-old female White Roman geese were divided at random into 6 groups with 6 dietary treatments. Diets were isoenergetic and isonitrogenous and contained alfalfa meal, barley bran, rice hulls, cellulose, pectin or lignin as the major dietary source of fibre. 3. Food intake was significantly higher in the barley bran group than in the other groups. Both daily weight gain and food conversion of the pectin and alfalfa meal groups were lower than those of the other groups. 4. In the 9-week-old geese, the relative weight and the length of the small intestine did not significantly differ among treatment groups. However, the relative weight was significantly lightest and the caecal length was significantly shortest ( P 0.05) in the pectin group. 5. Activities of amylase and cellulose hydrolases of the caecal contents were also highest in the pectin group. 6. From SEM micrographs, no morphological damage of the villi was observable in the different intestinal segments of the geese in any of the treatments.  相似文献   

Suppression of influenza virus infection by the orf virus isolated in Taiwan     

Fong-Yuan LIN  Yeu-Yang TSENG  Kun-Wei CHAN  Shu-Ting KUO  Cheng-Hsiung YANG  Chi-Young WANG  Masaki TAKASU  Wei-Li HSU  Min-Liang WONG 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(9):1055-1062

Orf virus (ORFV), a member of parapoxvirus, is an enveloped virus with genome of double-stranded DNA. ORFV causes contagious pustular dermatitis or contagious ecthyma in sheep and goats worldwide. In general, detection of viral DNA and observing ORFV virion in tissues of afflicted animals are two methods commonly used for diagnosis of orf infection; however, isolation of the ORFV in cell culture using virus-containing tissue as inoculum is known to be difficult. In this work, the ORFV (Hoping strain) isolated in central Taiwan was successfully grown in cell culture. We further examined the biochemical characteristic of our isolate, including viral genotyping, viral mRNA and protein expression. By electron microscopy, one unique form of viral particle from ORFV infected cellular lysate was demonstrated in the negative-stained field. Moreover, immunomodulating and anti-influenza virus properties of this ORFV were investigated. ORFV stimulated human monocytes (THP-1) secreting proinflammatory cytokines IL-8 and TNF-α. And, pre-treatment of ORFV-infected cell medium prevents A549 cells from subsequent type A influenza virus (IAV) infection. Similarly, mice infected with ORFV via both intramuscular and subcutaneous routes at two days prior to IAV infection significantly decreased the replication of IAV. In summary, the results of a current study indicated our Hoping strain harbors the immune modulator property; with such a bio-adjuvanticity, we further proved that pre-exposure of ORFV protects animals from subsequent IAV infection.  相似文献   

騰格里沙漠地区沙地土壤微生物学特性的研究   总被引：3，自引：0，他引：3  

張憲武  許光輝 《土壤学报》1962,10(3):227-234

沙漠的严重危害主要是流沙的移动。因此,沙漠改造和治理中的重要工作之一。是采取各种措施固定流沙^[1]。一般說来,固定流沙有两种方法:一种是植物固沙,一种是机械固沙。机械固沙是暂时的固沙法,为固定流沙不可缺少的一环;而植物固沙是一种最根本最可靠的永久固沙方法^[2,3]流沙一经生长植物,它的基本性质就要改变,形成固定沙丘。这就为进一步改造利用沙漠,创造了先决条件。时的固沙法,为固定流沙不可缺少的一环;而植物固沙是一种最根本最可靠的永久固沙方法^[2,3]流沙一经生长植物,它的基本性质就要改变,形成固定沙丘。这就为进一步改造利用沙漠,创造了先决条件。  相似文献   

The effects of jingsongling, a xylazine analog, on mean arterial blood pressure and heart rate in dogs — influences of yohimbine, tolazoline, prazosin, and atropine     

W. H. HSU  YAO-FANG RONG  F. B. HEMBROUGH 《Journal of veterinary pharmacology and therapeutics》1989,12(3):283-288

The effects of jingsongling (JSL) and xylazine on heart rate (HR) and mean arterial pressure (MAP) were studied in five conscious male dogs. An i.v. injection of xylazine (1 mg/kg) caused a bradycardia, an initial hypertension, and a subsequent hypotension. An i.v. injection of JSL (1 mg/kg) caused a bradycardia and a 20-min hypertension without a subsequent hypotension. Atropine sulfate (45 micrograms/kg, i.v.) increased HR for 30 min without changing MAP, and antagonized JSL-induced bradycardia for at least 60 min. There was a subsequent rebound bradycardia. Atropine sulfate potentiated JSL-induced hypertension in both magnitude and duration. Yohimbine (0.1 mg/kg, i.v.), an alpha 2-adrenoceptor antagonist, increased HR and MAP for 110 and 70 min, respectively. Yohimbine not only failed to potentiate but even reversed the pressor effect of JSL in a dose-dependent manner. Yohimbine also caused a dose-dependent reversal of JSL-induced bradycardia. Tolazoline (5 mg/kg, i.v.), a nonselective alpha-adrenoceptor antagonist, increased MAP for 20 min without changing HR. Tolazoline also reversed JSL-induced hypertension and bradycardia. Prazosin (1 mg/kg), an alpha 1-adrenoceptor antagonist, decreased MAP and increased HR for at least 110 min. Prazosin reversed JSL-induced hypertension but failed to affect JSL-induced bradycardia. These results indicated that: (1) JSL-induced bradycardia and hypertension are mediated by alpha 2-adrenoceptors; (2) yohimbine and tolazoline may be useful in antagonizing these untoward reactions associated with JSL administration, whereas prazosin and atropine were not found to be beneficial in this regard.  相似文献   

小米紅叶病的研究Ⅲ.小米紅叶病的传染方法     

裴美云  許順根 《植物病理学报》1958,4(2):87-93

 比較大規模的传病試驗的結果証知小米红叶病病毒不借种子传播,很难或者不能用机械式方法传染。  相似文献   

生长刺激剂及微量元素对于棉苗保健作用的效应     

許如琛  錢清海 《植物病理学报》1957,3(2):183-191

 过去,国內外許多学者証明,适当的应用微量元素和生长刺激剂处理种籽,对农作物苗期生长有促进作用,也常常收到提高产量的效果。关于应用于棉籽处理方面,波波甫应用了溴化鉀浸种,显著的提高了棉花的产量。  相似文献