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Tadahisa MASHITA Hiroaki KAMISHINA Yuya NAKAMOTO Yosuke AKAGI Ataru NAKANISHI Yusuke HARASAKI Tsuyoshi OZAWA Takashi UEMURA Yui KOBATAKE Shunsuke SHIMAMURA Naoki KITAMURA Sadatoshi MAEDA Yuji UZUKA Gerry SHAW Jun YASUDA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(4):433-438
The aim of this study was to evaluate the prognostic value of concurrent measurement of
serum phosphorylated neurofilament heavy subunit (pNF-H) concentration and intramedullary
T2W hyperintensity in paraplegic to paraplegic dogs. Our hypothesis was that concurrent
measurement of these would provide a more accurate prediction of functional outcome in
dogs with thoracolumbar intervertebral disc herniation (IVDH). A prospective case-control
clinical study was designed using 94 dogs with acute onset of thoracolumbar IVDH. The
association of serum pNF-H concentration, T2W hyperintensity on sagittal MRI (T2H/L2),
deep pain perception and surgical outcome were evaluated with logistic regression analysis
after three months for all 94 surgically treated dogs. Sensitivity to predict
non-ambulatory outcome was compared among pNF-H and T2H/L2 and combination of both.
Logistic regression analysis indicated that serum pNF-H concentration and T2H/L2 were
significantly correlated with surgical outcome (P<0.05); however, deep
pain perception was not (P=0.41). The results of logistic regression
analysis indicated that the odds ratios of unsuccessful long-term outcome were 2.6 for
serum pNF-H concentration, 1.9 for T2H/L2 and 2.3 for deep pain sensation. The sensitivity
and specificity to predict non-ambulatory outcome for using serum parameter pNF-H>2.6
ng/ml, using T2H/L2 value of>0.84 and using both
serum pNF-H and T2H/L2, were 95% and 75.7%, 65% and 86.5%, and 90.0% and 97.5%,
respectively. Therefore, combined measurements of serum pNF-H and T2H/L2 might be useful
for predicting long-term outcome in dogs with thoracolumbar IVDH. 相似文献
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SHINJI TAMURA YUMIKO TAMURA YUYA NAKAMOTO TSUYOSHI OZAWA KAZUYUKI UCHIDA 《Veterinary radiology & ultrasound》2009,50(2):178-181
Histiocytic sarcomas are characterized by proliferation and/or infiltration of neoplastic histiocytes localized to specific organs, unlike malignant histiocytosis which involves many organ systems. Only a few cranial histiocytic sarcomas have been reported. Here we describe four dogs that presented with neurological deficits referable to the forebrain, and were diagnosed histologically as having histiocytic sarcoma. Using magnetic resonance (MR) imaging, the tumors were characterized by a T2-hyperintense and T1-isointense mass in one dog, T2- and T1-isointense extraaxial masses in two dogs, and a diffuse T2-hyperintense lesion over the left cerebral cortex in one dog. All tumors had contrast enhancement. MRI features in three of the four dogs were similar to that of meningioma, supported by the observation of a dural tail in two of these three dogs, and a broad base of attachment in the other. In the other dog the imaging findings were similar to those of encephalitis. Intracranial histiocytic sarcoma does not appear to have specific MR imaging features and can be confused with meningioma or encephalitis. 相似文献
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James K. CHAMBERS Shinya IWASAKI Shigeki IMAMOTO Yuya NAKAMOTO Kazuyuki UCHIDA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2022,84(5):634
A two-months-old, male, mixed breed cat presented with epileptic seizures. The cat was diagnosed with drug-resistant epilepsy, and died at 3-years of age. No gross lesion was found at necropsy. Histopathologically, the dentate gyrus granule cell layer of the hippocampus was irregularly arranged. Granule cells were dispersed and ectopic cells were sporadically observed in the molecular layer. The granule cells had an enlarged cytoplasm and swollen nucleus. Immunohistochemistry for NeuN and GFAP confirmed severe neuronal loss and mild gliosis in CA1. Binucleation and ischemic change were observed in the remaining pyramidal cells. This report describes a case of feline temporal lobe epilepsy and hippocampal sclerosis associated with dentate gyrus malformation. 相似文献
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小南瓜是北方半干旱区增加经济产值的适生作物之一。该试验以日本"赤甘栗"小南瓜品种为试材,在3种密度(1 666、2 500、5 000株·hm~(-2))、2个灌溉量(3~4、6~8mm·d~(-1))和4个牛粪氮添加水平(N 25、50、75、100kg·hm~(-2))处理下进行大田试验,研究不同水、氮供应及种植密度对小南瓜产量的影响。结果表明:在中密度和高密度栽培下,小南瓜产量会随着氮添加量的增加而增加,但未受灌溉量的影响,但水分生产率会随着灌溉量增加而降低;在低密度栽培下灌溉量和氮添加量的增加都会导致小南瓜产量的增加,且水分生产率随着氮的提高会相应提高但未受灌溉量的影响;内蒙古半干旱地区春末夏季气候有利于小南瓜的种植,在定植密度为1 667株·hm~(-2)时,随氮肥的提高小南瓜产量及水分生产率均可增加,在3~4、6~8mm·d~(-1)灌溉水平下小南瓜产量分别为6.99、15.34t·hm~(-2)。 相似文献
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KAE MIYAZAWA HIROYUKI TSUJI MAKOTO YAMAGATA HIROSHI NAKANO TOMOMI NAKAMOTO 《Weed Biology and Management》2004,4(1):24-34
Weed flora in a crop rotation of soybean, sugar beet, and spring wheat were studied under combinations of conventional and reduced tillage, biocide application, and chemical fertilization to investigate whether any combination of conservational practices offers the potential to increase weed community diversity while maintaining weed biomass at an acceptable level. Weed density increased under reduced biocide application. Weed density and size increased under manure compost application (with reduced chemical fertilization) because of weed seed introduction. Weed emergence from seeds dispersed in the previous year was greater under reduced tillage. Two-year individuals increased under a combination of reduced tillage, reduced biocide application and manure compost application. These increases in weed population density and size under conservational practices were yet not consistent; rather, they showed an annually fluctuating trend. In terms of weed diversity, species richness and Shannon's diversity index were higher under manure application because of the introduction of new species and probably as a result of suppression of weed growth and reproduction, which can reduce the chance of dominance by certain species. When combined with manure application, reduced tillage may offer the potential for increasing diversity by reducing the competitiveness of dominant species and facilitating establishment of new or minor species. 相似文献
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Takeshi TSURUTA Ryo INOUE Takamitsu TSUKAHARA Mitsunori NAKAMOTO Hiroshi HARA Kazunari USHIDA Takaji YAJIMA 《Animal Science Journal》2012,83(12):799-804
A large amount of secretory immunoglobulin A (S‐IgA) is secreted in the alimentary tract of mammals. It has been reported that S‐IgA coats a portion of commensal intestinal bacteria in human and mouse. However, S‐IgA‐coated bacteria have not been studied in pigs and calves. In this study, we evaluated the distribution of S‐IgA‐coated commensal intestinal bacteria in each portion of the gastrointestinal tracts of pigs and calves. Immunoglobulin G (IgG)‐coated bacteria were also analyzed because a considerable amount of IgG is secreted in the gastrointestinal tracts of pigs, and in particular, calves. S‐IgA‐ or IgG‐coated bacteria were detected in all the segments of the gastrointestinal tracts of pigs and calves. The proportion of S‐IgA‐coated bacteria to total bacteria (i.e. S‐IgA coating ratio) varied in the segments of the gastrointestinal tract in pigs, whereas those of calves were nearly the same throughout the gastrointestinal tract. The S‐IgA and IgG coating ratios were higher in pigs than in calves for all segments of the gastrointestinal tract. 相似文献
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