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根据兽药管理依法行政的要求,<兽药管理条例>在明确兽药许可事项的实施机关、条件、程序、期限,完善兽药监督管理措施,建立责任追究制度等方面进行了全面的修订.兽药监督管理是依法行政的重要内容,是依法行政的一种具体体现和表现形式.在兽药监督管理中推进依法行政,必须加强兽药管理立法工作,加强制度建设,加强监督队伍建设,加强对行政权力的监督. 相似文献
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随着对鸡传染病防制技术水平的提高和相应的高科技产品的推广运用,加上政府和广大养鸡场（户）对典型新城疫（ND）和高致病性禽流感（HPAIH5亚型）防制工作的重视,成功地控制了这两种疾病的发生。但当前肉鸡业最易忽视、危害又最大的却是非典型新城疫（CND）和低致病力H9亚型禽流感（LPAI）。所谓“重视”是大家都接种了AI和ND疫苗,而忽视的是对AI只接种H5亚型而未接种H9亚型禽流感疫苗; 相似文献
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BC Li W Li H Chen YN Zhang ZT Zhang XY Wang B Gao TC Dou KH Wang 《Reproduction in domestic animals》2013,48(3):368-372
This study was conducted to explore the influencing factors of ova in vitro fertilization (IVF) and transfer of the fertilized ova into the oviduct of recipient hens. The efficiency of fertilization was compared using three aspects: (i) the different time of ova collection and transfer, (ii) egg‐laying period of recipient hen; and (iii) semen volume. The following results are observed: 72%, 40% and 0% of ova were found in ovarian sac in 30～40 min, 50～60 min and more than 90 min post‐oviposition, respectively; 20%, 18%, 14% and 5.8% of ova were fertilized with 0.1, 0.2, 0.5 and 1.0 ml semen, respectively; and 33% and 100% of healthy chickens were hatched from fertile ova with 0.1 and 0.5 ml of semen, respectively. All oocytes obtained from ovary and mid‐oviduct were unfertilized. Embryos were transferred into recipient hens 30 min ± 10 min post‐oviposition, and 70% of shelled eggs were produced. There were no eggs produced in the other transfer times. This demonstrated that live chicken can be obtained by IVF of ova collected shortly after oviposition. It was important that the ovum was transferred into the oviduct infundibulum of recipient hens immediately or shortly after oviposition. 相似文献
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miRNA and piRNA expression profiles of breeder cock testes detected by next‐generation sequencing 
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下载免费PDF全文 SR Wu W Guo YL Li XC Ren XY Lei XY Li JH Yao XJ Yang 《Reproduction in domestic animals》2017,52(2):203-213
miRNAs are small non‐coding regulatory RNAs that play key roles in diverse biological processes. In this study, we used the Solexa sequencing technique to profile miRNAs in breeder cock testes to illustrate their functions. A total of 663 co‐expressed miRNAs and 3,180 co‐expressed piRNAs were detected in three libraries. Based on Mir‐X? miRNA qRT‐PCR, three miRNAs representing low, medium and high expression levels according to the sequencing results were selected randomly to validate the miRNAs' expression profiles. Results suggested that the miRNA expression profiles data could represent actual miRNA expression levels. Moreover, target genes prediction of the co‐expressed miRNAs and further Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed, which revealed that some candidate miRNAs were involved in the regulation of the spermatogenesis process, spermatozoa function and testicular metabolism. In conclusion, we provided a useful resource for further elucidation of the miRNAs' regulatory role in spermatogenesis, contributing to a preliminary database for functional and molecular mechanistic studies in testicular metabolism, spermatogenesis and other testes functions. 相似文献
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XY Zeng JA Turkstra DFM van de Wiel DZ Guo XY Liu RH Meloen WMM Schaaper FQ Chen HB Oonk & X Zhang 《Reproduction in domestic animals》2001,36(2):101-105
We have investigated, under the normal conditions of local Chinese pig farming, castration of young male pigs by vaccination with a newly developed vaccine against gonadotrophin releasing hormone (GnRH). Because of the very early onset of puberty, long fattening period and relatively harsh circumstances in Chinese pig production, an investigation of the endocrine response of Chinese breeds to this type of vaccination was of particular interest. Fifteen crossbred boars (Yorkshire × Yanan) from three different litters were randomly assigned to three groups of five animals each. The first group was immunized at 13 weeks of age with a GnRH tandem dimer OVA‐conjugate in Specol and received a booster immunization 8 weeks later. The second group was injected with Specol alone and served as untreated controls. The remaining group was surgically castrated at the time of weaning (at 6 weeks of age). Pigs were fed ad libitum from weaning onwards. All animals were slaughtered at 31 weeks of age. Immunized boars had undetectable or low serum testosterone (0.09 ± 0.12 ng/ml), low fat androstenone (0.05 ± 0.01 μg/g) levels and very low testes weights (19.1 ± 4.3 g). Intact controls had much higher serum levels of testosterone (9.76 ± 4.81 ng/ml), fat androstenone levels (2.26 ± 0.87 μg/g) and testes weights (114.3 ± 29.41 g) at slaughter. Both the immunized and castrated group grew significantly faster than intact boars (p < 0.01). Average daily gains in immunized, castrated and intact animals were 0.69 ± 0.08, 0.63 ± 0.05 and 0.42 ± 0.07 kg (mean ± SD), respectively. The present data demonstrate for the first time that the newly developed anti‐GnRH vaccine works very well under practical Chinese pig farming conditions, and can be an attractive alternative to surgical castration. 相似文献