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Zhanerke Akhatayeva Cui Mao Fugui Jiang Chuanying Pan Chunjian Lin Kunjie Hao Tianxin Lan Hong Chen Qingfeng Zhang Xianyong Lan 《Reproduction in domestic animals》2020,55(11):1470-1478
Growth hormone and prolactin belong to the class of peptide hormones that have a wide range of regulatory functions. In this study, polymorphisms of growth hormone receptor (GHR) and prolactin (PRL) genes were analysed as candidate genes, which are responsible for the litter size in Australian White (AUW) sheep. According to the statistical analyses results, the polymorphism information content (PIC) values of the PRL-P1-ins-23 bp, GHR-P2-del-23 bp and GHR-P8-del-23 bp were 0.371, 0.366 and 0.375, respectively, which indicates the high genetic polymorphism in AUW sheep. Moreover, all indel loci are not conformed to the HWE (p < .05). Further, our findings revealed that the PRL-P1-ins-23 bp polymorphism in the ovine PRL gene was significantly related to the first parity litter size (p = .001) and the DD genotype displaying the highest genotypic mean. Meanwhile, the GHR-P2-del-23 bp and GHR-P8-23 bp indels in the ovine GHR gene were significantly correlated with first parity litter size (p < .05), and the individuals with the genotype II showed significantly higher litter size than others. Collectively, these results demonstrated that our findings could be useful for future sheep breeding strategies based on the molecular-assisted selection (MAS). 相似文献
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为充分了解国内、外山羊产羔数的研究现状和发展趋势,为我国山羊繁殖领域提供新思路,运用文献计量学方法,以“山羊产羔数”为检索词,在Web of Science核心合集数据库（1992-2022年）和CNKI数据库（1958-2022年）中进行主题精准检索,并运用Excel 2019、GraphPad Prism v5.01和VOS viewer等软件分别对1958-1991年、1992-2001年、2002-2011年和2012-2022年四个时间段的年度发表文献数量、各国家发表论文情况、机构、作者、期刊、关键词、研究方向等方面进行可视化分析,并对结果进行总结和概述。研究发现：我国在“山羊产羔数”方面的研究呈整体上升趋势,具有较大的发展潜力,正逐渐走向世界领先地位,但我国发表论文篇均被引频次仍与法国等国家存在差距;我国学者在注重发表论文数量的同时,还应注重研究的创新性和实践性,从而使得所发表论文在国际上展现更深远的影响力。 相似文献
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