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1.
Turan S Topcu A Karabulut I Vural H Hayaloglu AA 《Journal of agricultural and food chemistry》2007,55(26):10787-10794
The fatty acid, sn-2 fatty acid, triacyglycerol (TAG), tocopherol, and phytosterol compositions of kernel oils obtained from nine apricot varieties grown in the Malatya region of Turkey were determined ( P<0.05). The names of the apricot varieties were Alyanak (ALY), Cataloglu (CAT), C?loglu (COL), Hacihaliloglu (HAC), Hacikiz (HKI), Hasanbey (HSB), Kabaasi (KAB), Soganci (SOG), and Tokaloglu (TOK). The total oil contents of apricot kernels ranged from 40.23 to 53.19%. Oleic acid contributed 70.83% to the total fatty acids, followed by linoleic (21.96%), palmitic (4.92%), and stearic (1.21%) acids. The s n-2 position is mainly occupied with oleic acid (63.54%), linoleic acid (35.0%), and palmitic acid (0.96%). Eight TAG species were identified: LLL, OLL, PLL, OOL+POL, OOO+POO, and SOO (where P, palmitoyl; S, stearoyl; O, oleoyl; and L, linoleoyl), among which mainly OOO+POO contributed to 48.64% of the total, followed by OOL+POL at 32.63% and OLL at 14.33%. Four tocopherol and six phytosterol isomers were identified and quantified; among these, gamma-tocopherol (475.11 mg/kg of oil) and beta-sitosterol (273.67 mg/100 g of oil) were predominant. Principal component analysis (PCA) was applied to the data from lipid components of apricot kernel oil in order to explore the distribution of the apricot variety according to their kernel's lipid components. PCA separated some varieties including ALY, COL, KAB, CAT, SOG, and HSB in one group and varieties TOK, HAC, and HKI in another group based on their lipid components of apricot kernel oil. So, in the present study, PCA was found to be a powerful tool for classification of the samples. 相似文献
2.
David W. Green Matthew P. Padula Jerran Santos Joshua Chou Bruce Milthorpe Besim Ben-Nissan 《Marine drugs》2013,11(4):1203-1220
A vital ingredient for engineering bone tissue, in the culture dish, is the use of recombinant matrix and growth proteins to help accelerate the growth of cultivated tissues into clinically acceptable quantities. The skeletal organic matrices of calcifying marine invertebrates are an untouched potential source of such growth inducing proteins. They have the advantage of being ready-made and retain the native state of the original protein. Striking evidence shows that skeleton building bone morphogenic protein-2/4 (BMP) and transforming growth factor beta (TGF-β) exist within various marine invertebrates such as, corals. Best practice mariculture and the latest innovations in long-term marine invertebrate cell cultivation can be implemented to ensure that these proteins are produced sustainably and supplied continuously. This also guarantees that coral reef habitats are not damaged during the collection of specimens. Potential proteins for bone repair, either extracted from the skeleton or derived from cultivated tissues, can be identified, evaluated and retrieved using chromatography, cell assays and proteomic methods. Due to the current evidence for bone matrix protein analogues in marine invertebrates, together with the methods established for their production and retrieval there is a genuine prospect that they can be used to regenerate living bone for potential clinical use. 相似文献
3.
Macrolides are considered to be one of the safest anti-infective groups in clinical use, with severe adverse reactions being rare. However, there are limited data about their embryotoxicity and teratogenicity. We aimed to investigate and compare the effects of these agents on embryonic growth and development. Rat embryos were cultured in vitro for 48 h in rat serum. Whole rat serum was used as a culture medium for the control group while different concentrations of spiramycin and azithromycin (1.25-6.25 microg/ml), and clarithromycin (2.5-30 microg/ml) were added to rat serum for the experimental groups. Dose-dependent effects of macrolides on embryonic developmental parameters were compared using morphological methods. Embryos were evaluated for the presence of any malformations. After morphological examination of the embryos, total DNA was extracted from the cells using standard procedures to determine fragmentation of nuclear DNA of embryonic cells. When compared with the control embryos, the macrolides significantly decreased all growth and developmental parameters dose dependently. While clarithromycin was found to cause more developmental toxicity than spiramycin and azithromycin, azitromycin was determined to have more teratogenicity potential. Compared with controls, there was no difference regarding the fragmentation of nuclear DNA of all the agents used. According to these results, when the toxic and teratogenic potential of the used agents compared, because of the lower toxic and teratogenic effects observed with spiramycin, this agent may be preferred for parturients. 相似文献
4.
Ozgun Kalkisim Zuhal Okcu Besim Karabulut Duygu Ozdes Celal Duran 《Erwerbs-Obstbau》2018,60(2):173-181
The aim of the present research was to investigate the fruit quality of twenty different local pear varieties (Pyrus communis L.), namely Ahlat, Ankara, Arpa, B?ld?rc?n, Çermai, Cinci, Gelin Bo?an, Hac? Hamza, Hah?r, Kabak, K?z?l, Kokulu, Mehrani, Menendi, Sulu, ?algam, Tokat Sultan?, Tur?u, Yaz, and Yaz Meyri?i, grown in Gumushane province in terms of pomological and morphological characteristics and chemical compositions. The fruit mass, fruit width and length, fruit stem thickness and length, fruit kernel width and length, hardness of pulp, number of seeds, leaf width and length, leaf stem length and thickness, and water soluble dry matter (WSDM) of the pear fruits have been determined as pomological and morphological characteristics. On the other hand, the chemical compositions of the pear varieties have been evaluated in terms of protein, ash, sucrose, fructose, glucose, total sugar, titratable acidity, moisture, and mineral element levels.Both pomological and morphological results demonstrated that the local pear varieties are important in terms of rehabilitation studies and detailed selection studies on these local varieties should be performed. The chemical analyses result of the pear varieties revealed that there is no component that may be harmful to human health when consumed, and also these varieties contains the necessary amount of mineral elements. 相似文献
5.
Ozgun Kalkisim Duygu Ozdes Zuhal Okcu Besim Karabulut Hasan Basri Senturk 《Erwerbs-Obstbau》2016,58(1):41-48
The present study was conducted in order to determine the pomological and morphological characteristics and chemical compositions of some local apple varieties grown in Gumushane. As a result of field work in Gumushane province, sixteen different apples, which are Summer Apple, English apple, Green Belly, Black Belly and Yellow Belly Apples, Amasya Marble, Bey Apple, Chest Apple, Mahsusa, Arabian Girl, Willow Apple, Tav?anba??, Yellow H?d?r, Local Marble, Bride Apple, and Fatty Apple were collected in order to analyze. The average results of pomological and morphological properties and chemical compositions were obtained as following: fruit mass; 127.36 g, fruit width; 65.23 mm, fruit length; 57.30 mm, fruit stalk thickness; 2.17 mm, fruit stalk length; 17.63 mm, stalk pit depth; 12.75 mm, flower pit depth; 10.29 mm, fruit firmness; 13.79 kg/cm2, seed house width; 15.89 mm, seed house length; 17.39 mm, number of seeds; 4.3, water soluble dry matter content; 14.53?%, ash content; 1.11?%, pH; 3.8, titratable acidity; 0.69 g/L, water content; 83.8?%, reducing sugar; 5.04 g/100 g, sucrose; 2.25 g/100 g, and the amount of total sugars; 7.29 g/100. The fruit peel color was determined by considering the light transmittance (L). The average L values were ranged between 112.06 and 66.32. On the other hand among the mineral elements, potassium and manganese amounts were determined as the highest and the lowest, respectively. 相似文献
6.
Ozgun Kalkışım Melih Okcu Zuhal Okcu Besim Karabulut Nalan Yildirim Guleray Agar 《Erwerbs-Obstbau》2016,58(4):259-264
Thirty one pears genotypes from east blacksea region were evaluated for genetic relationships by using Randomly Amplified Polymorphic DNA (RAPD) and ISSR (Inter-Simple Sequence Repeats) markers from total 70 RAPD and ISSR primer investigated, 22 could amplify clearly and consistently. Cluster analysis of the pears genotypes was performed based on data from polymorphic bands RAPD and ISSR by using Jaccard’s similarity coefficient and the Unweighted pair-group method with arithmetic average (UPGMA) clustering method. The 31 pear genotypes were classified into two major groups. Cluster A was divided into 2 subclusters: Gumushane pears and Trabzon pears. Cluster B consisted of Artvin pears. The similarity matrix values ranged between 0.105 and 0.968. 相似文献
7.
Recent studies show that earthquake faults may rupture at speeds exceeding the shear wave velocity of rocks. This supershear rupture produces in the ground a seismic shock wave similar to the sonic boom produced by a supersonic airplane. This shock wave may increase the destruction caused by the earthquake. We report that supershear earthquakes are characterized by a specific pattern of aftershocks: The fault plane itself is remarkably quiet whereas aftershocks cluster off the fault, on secondary structures that are activated by the supershear rupture. The post-earthquake quiescence of the fault shows that friction is relatively uniform over supershear segments, whereas the activation of off-fault structures is explained by the shock wave radiation, which produces high stresses over a wide zone surrounding the fault. 相似文献
8.
Bouchon M Karabulut H Aktar M Ozalaybey S Schmittbuhl J Bouin MP 《Science (New York, N.Y.)》2011,331(6019):877-880
Laboratory and theoretical studies suggest that earthquakes are preceded by a phase of developing slip instability in which the fault slips slowly before accelerating to dynamic rupture. We report here that one of the best-recorded large earthquakes to date, the 1999 moment magnitude (M(w)) 7.6 Izmit (Turkey) earthquake, was preceded by a seismic signal of long duration that originated from the hypocenter. The signal consisted of a succession of repetitive seismic bursts, accelerating with time, and increased low-frequency seismic noise. These observations show that the earthquake was preceded for 44 minutes by a phase of slow slip occurring at the base of the brittle crust. This slip accelerated slowly initially, and then rapidly accelerated in the 2 minutes preceding the earthquake. 相似文献
9.
Ali Tuğrul Akin Emel Öztürk Emin Kaymak Derya Karabulut Birkan Yakan 《Anatomia, histologia, embryologia》2021,50(6):908-917
Cancer is a lethal disease that is characterized by uncontrolled cell division and proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic agent used for treatment of many cancer types, but it induces serious hepatotoxicity. In this study, we aimed to determine possible hepato-therapeutic effects of thymoquinone (THQ) on DOX-induced hepatotoxicity in rats. Rats were divided into five groups (n = 8): Control, THQ (10 mg/kg/day/i.p for 14 days), Olive Oil (equal volume with THQ for 14 days), DOX (single dose, 15 mg/kg/i.p on 7th day) and DOX + THQ (10 mg/kg/day/i.p and DOX 15 mg/kg/i.p on 7th day). At the end of the experiment, liver tissues were extracted and evaluated histopathologically. eNOS, iNOS and Cas-3 immunostaining were performed to determine the expression levels. TUNEL method was used to determine apoptotic index. Furthermore, liver tissue total antioxidant status (TAS), total oxidant status (TOS), TNF-α and TGF-β levels were measured by ELISA assay. The DOX group showed histopathological deterioration compared to Control group. Moreover, apoptotic index, eNOS, iNOS and Cas-3 expressions increased in DOX group. While TAS level of the DOX group decreased, TOS level increased. TNF-α and TGF-β levels increased in DOX group. However, there was improvement in DOX + THQ group compared to DOX group. Moreover, apoptotic cell number, eNOS, iNOS and Cas-3 expressions decreased in DOX + THQ group compared to DOX group. We concluded that thymoquinone can be used as a phytotherapeutic for reducing DOX-induced liver damage. 相似文献
10.
A. Ka&#;an Karabulut B. Köylüo&#;lu & &#;lknur Uysal 《Anatomia, histologia, embryologia》2001,30(3):141-146
This study investigated the value of prenatal ultrasonographic measurements of sacrum as a predictor of in utero development and gestational age (GA), and to make a comparison between the data obtained by ultrasonography and dissection. A prospective cross-sectional study of ultrasonography was conducted in 186 pregnant women with uneventful single pregnancies. GA ranged from 14 to 40 weeks, and the relationships of sacrum length (SL) with GA, femur length (FL), biparietal diameter (BPD), head circumference (HC) and abdominal circumference (AC) were evaluated. In addition, the sacral bones of 101 spontaneously aborted foetuses aged from 13 to 39 weeks were dissected and measured. The relationship of the results with GA was investigated. There was a linear relationship between the ultrasonographic measurements of the SL and the GA (R2 = 0.93, P < 0.001), the FL (R2 = 0.93, P < 0.001), the BPD (R2 = 0.93, P < 0.001), the HC (R2 = 0.92, P < 0.001) and the AC (R2 = 0.90, P < 0.001). The rate of increase of SL was significantly higher before 28 weeks of gestation than in later pregnancy, with a correlation coefficient between SL and GA of 0.96 and 0.88, respectively. The SL measurements obtained by dissection were similar to those of ultrasonography. There was a linear relationship between the SL and the GA (R2 = 0.96, P < 0.001) and the correlation coefficients between SL and GA were 0.97 before 28 weeks of gestation, and 0.94 in later weeks. In conclusion, this study demonstrates a high correlation between the SL, GA and other standard measurements of foetal growth, and suggests that SL measurement is a valuable predictor of GA in the foetuses with normal growth. 相似文献