Histologic characteristics and local cellular immunity of the gland of the third eyelid after topical ophthalmic administration of 2% cyclosporine for treatment of dogs with keratoconjunctivitis sicca   总被引：1，自引：0，他引：1  

Izci C  Celik I  Alkan F  Ogurtan Z  Ceylan C  Sur E  Ozkan Y 《American journal of veterinary research》2002,63(5):688-694

OBJECTIVE: To evaluate the efficacy of topical administration of a 2% solution of cyclosporine (CsA) for treatment of dogs with keratoconjunctivitis sicca (KCS) and to correlate results with histopathologic characteristics and local cellular immunity of the gland of the third eyelid. ANIMALS: 24 dogs with bilateral KCS. PROCEDURE: Lacrimal secretion was measured, using Schirmer tear test (STT) strips. Leukocyte and T-lymphocyte subsets were determined in blood samples. Histopathologic changes as well as CD4+, CD8+, and alpha-naphthyl-acetate esterase-positive (ANAE+) lymphocytes were evaluated. RESULTS: Clinical signs resolved at the end of 1 month in conjunction with significantly increased STT values, compared with baseline values. Fifteen and 30 days after discontinuation of CsA treatment, a decrease was observed in STT values in both eyes; however, only values for the right eye were significantly different. There was a significant decrease in the number of lymphocytes and ANAE+ lymphocytes 15 and 30 days after discontinuation of CsA treatment, compared with baseline values. Differences were not observed in number of CD4+ lymphocytes among treatment groups. However, there was a significant decrease in number of CD8+ lymphocytes with reversal of the CD4+:CD8+ in both eyes after CsA treatment for 30 days, compared with the control group. Increased secretory activity and decreased lymphocyte infiltration were characteristic histopathologic findings. CONCLUSIONS AND CLINICAL RELEVANCE: Topical administration of a 2% solution of CsA was effective for the treatment of dogs with KCS. Strict follow-up monitoring is required after the cessation of treatment because of the possibility of recurrence of KCS.  相似文献   

Effect of seasonal conditions on oestrus occurrence and postpartum period in Anatolian water buffaloes     

Aksoy M  Kaya A  Uçar M  Lehimcioglu N  Tekeli T 《DTW. Deutsche tier?rztliche Wochenschrift》2002,109(9):416-418

Oestrus and calving records of Anatolian buffaloes were analyzed to investigate influence of climatic conditions on oestrus occurrence and postpartum period. Oestrus records showed a seasonal pattern concentrated between July and September which is the warmest period of the year. Likewise, more than half (52.7%) of the total calvings occurred between May and August. Month of calving significantly influenced the length of calving to first oestrus interval and open period (P < 0.01). The average length of open period was significantly shorter in autumn and summer calvers compared to those calved in spring and winter (P < 0.05) during long days. The humidity rate was negatively correlated with both calving to first oestrus interval and open period (P < 0.05). In conclusion, exposure to high environmental temperatures around 20 degrees C exerted no suppressive influence on ovarian activity in Anatolian buffaloes. Although humidity rate (P < 0.05) and ambient temperature (P < 0.01) was found to be correlated with the duration of postpartum period, day length might be the main factor regulating reproductive biorhythm and postpartum events in Anatolian buffalo cows.  相似文献   

Comparison of different bronchial closure techniques following pneumonectomy in dogs     

Hakan Salci  A. Sami Bayram  Ozgur Ozyigit  Cengiz Gebitekin  O. Sacit Gorgul 《Journal of veterinary science (Suw?n-si, Korea)》2007,8(4):393-399

The comparison of the histologic healing and bronchopleural fistula (BPF) complications encountered with three different BS closure techniques (manual suture, stapler and manual suture plus tissue flab) after pneumonectomy in dogs was investigated for a one-month period. The dogs were separated into two groups: group I (GI) (n = 9) and group II (GII) (n = 9). Right and left pneumonectomies were performed on the animals in GI and GII, respectively. Each group was further divided into three subgroups according to BS closure technique: subgroup I (SGI) (n = 3), manual suture; subgroup II (SGII) (n = 3), stapler; and subgroup III (SGIII) (n = 3), manual suture plus tissue flab. The dogs were sacrificed after one month of observation, and the bronchial stumps were removed for histological examination. The complications observed during a one-month period following pneumonectomy in nine dogs (n = 9) were: BPF (n = 5), peri-operative cardiac arrest (n = 1), post-operative respiratory arrest (n = 1), post-operative cardiac failure (n = 1) and cardio-pulmonary failure (n = 1). Histological healing was classified as complete or incomplete healing. Histological healing and BPF complications in the subgroups were analyzed statistically. There was no significant difference in histological healing between SGI and SGIII (p = 1.00; p > 0.05), nor between SGII and SGIII (p = 1.00; p > 0.05). Similarly, no significant difference was observed between the subgroups in terms of BPF (p = 0.945; p > 0.05). The results of the statistical analysis indicated that manual suture, stapler or manual suture plus tissue flab could be alternative methods for BS closure following pneumonectomy in dogs.  相似文献   

Mycotox and aflatoxicosis in quails     

A. Sehu  S. Cakir  Ö. Cengiz  D. Essiz 《British poultry science》2006,47(2)

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Effects of varying nitrogen doses on yield,yield components and artemisinin content of Artemisia annua L.     

Menşure Özgüven  Bilge Şener  Ilkay Orhan  Nazım Şekeroğlu  Muzaffer Kirpik  Murat Kartal  Ipek Peşin  Zülküf Kaya 《Industrial Crops and Products》2008,27(1):60-64

Artemisia annua L. is an aromatic-antibacterial herb that destroys malarial parasites, lowers fevers and checks bleeding, and of which the secondary compound of interest is artemisinin. The objective of the present study was to determine yield, yield components and artemisinin content of A. annua L. grown under four nitrogen applications (0, 40, 80 and 120 kg ha⁻¹) in the Çukurova region of Turkey in 2004 and 2005. Field trials were conducted at Çukurova University, Agricultural Faculty Field Crops Department. In the study, plant height, number of branches, fresh herbage yield, dry herbage yield, fresh leaf yield, dry leaf yield, essential oil content and artemisinin content (by high performance liquid chromatography, HPLC) were examined. By analysis of variance, nitrogen doses had no any statistical effect on the traits investigated except for artemisinin content. Artemisinin content of the dried leaves were significantly affected by nitrogen applications, which varied from 6.32 to 27.50 mg 100 g⁻¹. Contents were from 120 and 80 kg ha⁻¹ nitrogen for the years of 2004 and 2005, respectively.  相似文献   

Genome-wide association studies of preweaning growth and in vivo carcass composition traits in Esme sheep     

Onur Yilmaz  Mehmet Kizilaslan  Yunus Arzik  Sedat Behrem  Nezih Ata  Orhan Karaca  Cengiz Elmaci  Ibrahim Cemal 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2022,139(1):26-39

Sheep are considered as a major contributor of global food security. Moreover, sheep preweaning growth traits as well as in vivo carcass composition traits such as ultrasonic measurements of Longissimus dorsi muscle depth (UMD) and back-fat thickness (UFD) are crucially important indicators of meat yield and hot carcass composition. Despite their relative importance for productivity and profitability of a sheep production system, detected QTL for these traits are quite scarce. Therefore, we implemented GWAS for these traits using animal mixed model-based association approach provided by GenABEL in Esme sheep. Three genome-wide and 14 individual chromosome-wide associated SNPs were discovered. As a result, ESRP1, LOC105613082, ZNF641, DUSP5, TEAD1, SMOX, PTPRT, RALYL, POM121C, PHIP, LOC101106051, ZIM3, PEG3, TRPC7, FBXL4, LOC105610397, LOC105616489 and DNAAF2 were suggested as candidates. Some of the discovered genes and involved pathways were already annotated to contribute growth and development in various species including human, mice and cattle. All in all, the results of this study are expected to strongly contribute to shed a light on the underlying molecular mechanisms behind growth and carcass composition traits, with potential implications on studies aiming faster genetic improvement, targeted low-resolution SNP panel designs and genome-editing studies.  相似文献   

A retrospective study of gastrointestinal disorders in a predominantly Austrian leisure horse referral hospital population     

V. Gunes  A. C. Onmaz  A. Pavaloiu  G. Kaya Karasu  R. van den Hoven 《Equine Veterinary Education》2022,34(9):467-472

The aim of our retrospective study was to produce and analyse epidemiological data on gastrointestinal (GI) disorders of Austrian leisure horses. Case records of horses referred to the Equine Clinic of the Veterinary University of Vienna were collected from an electronic hospital information system using its search options. All cases reported to have suffered a GI disorder between March 2003 and February 2015 were selected. In this period of 4314 days, data of 1833 GI cases, mostly accompanied by colic signs, were analysed. The vast majority of our GI cases appeared in the abdominal parts of the GI tract 96% (1760/1833) while just 1.3% (24/1833) could be definitively attributed to oesophageal disorders, whereas in 2.7% (49/1833) of the cases a definitive diagnosis could not be made. The highest prevalence of GI disorders was seen in July and October/November. A breakdown of figures for cases clustered under the colic syndrome showed that colon impactions in left ventral large and/or pelvic flexure (35%) were the major problem followed by gastric disorders (18%), spasmodic colic (9%), enteritis (7%), caecal tympany (6%); caecal impaction (4%), colitis (3%), abnormal anatomical positions of large colon including complete and partial strangulation/volvulus, nephrosplenic entrapment of the left ventral and dorsal colon and right dorsal displacement of the large colon (3%) and small intestinal volvulus (2.7%). In 12% of the cases, the cause of the abdominal discomfort was likely idiopathic paralytic ileus. The searching tool of the electronic patient data also brought up cases with malabsorbtion/IBD syndrome and GI ruptures, both these contributed less than 1% of the referred GI cases. Results suggested that the causes of colic are diverse, but the major reasons for referred cases of colic in the east Austrian horse population are large colon impaction or displacements. Seasonal distribution and specific causes of gastrointestinal disorders should be considered essential components of the initial clinical assessment of horses presenting with colic.  相似文献   

The forest garden system of Saparua island Central Maluku, Indonesia, and its role in maintaining tree species diversity     

M. Kaya  L. Kammesheidt  H.-J. Weidelt 《Agroforestry Systems》2002,54(3):225-234

The dusuns of Central Maluku which improve fallows by planting spice trees such as clove (Syzygium aromaticum syn. Eugenia aromatica), nutmeg (Myristica fragrans), or coconut (Cocos nucifera) and tending spontaneous regeneration, are an example of a species-rich forest garden system in the eastern hemisphere of the Indonesian archipelago. In this paper we report the influence of site conditions, as slope inclination, soil type, and soil depth, on species composition, tree species diversity, and stand structure in old dusuns in four villages on Saparua, a small island south of Seram. In addition, we compared the floristic composition and stand structure of old dusuns with those of primary forest and advanced fallow vegetation (∼15-yr old). Soil conditions, particularly the depth of the mineral soil layer, and the relief have a major influence on species selection in dusuns. The most common species in old dusuns were absent both in primary forest and forest fallow. Floristic similarity between old dusuns and the unmanaged stands was low. However, in two study villages species richness of old dusuns was similar to that of the primary forest. Old dusuns showed an open structure with an average reduction of basal area by about half compared to the primary forest. Less than half of all individuals found above 10 cm DBH in old dusuns were planted. Only very few species were exclusively planted. Most species were both planted and emerged from spontaneous regeneration. The results indicate the important role of spontaneous regeneration in this forest garden system. This revised version was published online in June 2006 with corrections to the Cover Date.  相似文献   

Variation in crushing strength and some related properties of a red pine     

Fikret Kaya BScFE  MScFE. Ph. D. candidate  Ian Smith BSc.  MSc.  PhD.  PEng.  FIWSc. 《Wood Science and Technology》1993,27(3):229-239

Summary Below-crown radial and height variations in maximum crushing strength parallel to grain, relative density and tracheid length of an immature, 55 year old, red pine were studied. All properties showed pronounced trends with radial age and increased from pith to bark. A radial age of 16 years was estimated as the age from which mature stem wood is formed. All properties studied varied with height above ground. Strong correlations were observed among properties. The study tree exhibited noticeably lower average crushing strength than is reported in the literature for wood from mature red pines.This work was undertaken with financial support from Karadeniz Technical University, Trabzon, Turkey, and the Natural Sciences and Engineering Research Council of Canada, Operating Grant 0GP0004417  相似文献   

Determination of the quality parameters of pike perch <Emphasis Type="Italic">Sander lucioperca</Emphasis> caught by gillnet,longline and harpoon in Turkey     

Gülsün Özyurt  Yesim Özogul  Caner Enver Özyurt  Abdurrahman Polat  Fatih Özogul  Cengiz Gökbulut  Beyza Ersoy  Esmeray Küley 《Fisheries Science》2007,73(2):412-420

ABSTRACT:   The effects of the different catching methods (gillnet, longline, harpoon) on sensory, chemical (pH, total volatile base nitrogen, K -value) and microbiological (total viable count [TVC]) changes in pike perch Sander lucioperca stored in ice were investigated. The same soaking time was used for both gillnet and longline fishing. The catching method had considerable influence on the freshness quality of pike perch. The acceptable shelf life was 15 days for pike perch caught by gillnet, and 22 days for longline and harpoon. The initial concentrations of inosine monophosphate (2.4 μmol/g) in pike perch caught by gillnet were significantly lower ( P  < 0.05) than longline (4.1 μmol/g), and especially by harpoon (16.7 μmol/g). However, the initial K -values for fish caught by harpoon were significantly ( P  < 0.05) lower (24.36%) than fish caught by longline and gillnet (57.69%, 64.41%, respectively). The average K , Ki, G and H -values at rejection day in terms of sensory assessment were approximately 90, 98, 156 and 40%, respectively, for all catching methods during ice storage. However, TVC reached 7.0 log cfu/g after approximately 11 days of storage for fish caught by gillnet, 19 days for fish caught by longline and 8 days for fish caught by harpoon. The result of this study suggests that the best catching method for preserving the freshness of pike perch is longline, based on the data obtained from the sensory and microbiological analysis.  相似文献