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Clinical lungworm disease appears to occur frequently in Dutch dairy herds. Because the clinical diagnosis is difficult to make in adult cattle, the clinical diagnosis, laboratory diagnosis, differential diagnosis, therapy, and prevention are discussed in this article. In addition, four cases of lungworm disease in adult cattle are presented. The main clinical complaints were coughing, decreased milk production, and weight loss. Several lactating cows died in one herd. The disease history of four herds revealed that introduction of susceptible cows or heifers to herds with cows with subclinical patent lungworm infections had resulted in a pasture infection, leading to clinical problems in both the newly introduced and 'resident' cows of the herd. Further history analysis of the fourth herd revealed that re-introduction of lungworm infection by newly purchased cows in a lungworm free herd resulted in clinical lungworm problems in adult and young animals. The fourth case led to the conclusion that lungworm infection must have been re-introduced by cows purchased from another farm.  相似文献   
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The significance of food allergy as a primary cause for gastrointestinal disturbances in domestic animals, especially calves and piglets, is discussed. The immunological backgrounds and pathogenesis are described in some detail. The clinical and pathological manifestations in animals are related to those in man. Diagnostic possibilities, therapy and prevention, as far as known in animals, are mentioned and, based on human experiences, further extensions are proposed.  相似文献   
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To test the value of a recently developed bulk-tank milk (BTM) ELISA for diagnosing (sub)clinical Dictyocaulus viviparus infection in lactating dairy herds under field conditions, bulk milk samples were collected from farms with or without clinical symptoms suspected to be caused by lungworm infection. Results of the BTM ELISA were compared against individual examinations for lungworm larvae in faeces and lungworm antibodies in serum from up to 20 heifers (parity 1) and up to 20 cows (parity ≥ 2) on the same farms. This also allowed, for the first time, to examine the value of individual faecal and serological examinations in the diagnosis of (sub)clinical lungworm infections. In total, 33 farms participated. Of these, 16 reported clinical symptoms possibly related to lungworm infection (defined as a suspected positive clinical status or CS(+)) and 17 reported having no such symptoms (CS(-)). In total, 503 heifers and 649 cows were sampled. Of all faeces samples positive for lungworm larvae, 94 were from heifers (18.9% of all heifers) and 75 from cows (11.7% of all cows) (P<0.001). Of all sera positive for lungworm antibodies, 130 were from heifers (26.1% of all heifers) and 113 from cows (17.5% of all cows) (P<0.001). Of the CS(-) farms 41% had at least one heifer or cow shedding larvae and 71% had at least one seropositive heifer or cow. Of the CS(+) farms this was 81% and 94%, respectively. There were only 4 farms, all CS(-), where none of the animals were found shedding larvae and all animals tested seronegative. This implies that on 76% of the CS(-) farms lungworm infection circulated unnoticed. On all CS(+) farms the suspicion that lungworm caused the respiratory symptoms was confirmed by the individual faecal and serological examinations, whereas the BTM ELISA confirmed presence of lungworm on half of the CS(+) farms. The latter in particular occurred on farms with the more severe outbreaks. Overall, of 32 available BTM samples 10 tested positive (8 of 15 CS(+) and 2 of 17 CS(-) farms). For diagnosing suspected lungworm disease it was concluded that testing a BTM sample might suffice in case of moderate to severe outbreaks. However, in case of a mild outbreak with just a few animals coughing, examining individual animals has to be preferred over testing a BTM sample. The likelihood to detect lungworm infection is higher if heifers are sampled compared to cows. Sensitivity of the BTM ELISA was 35.7% if the presence of at least one seropositive and/or one larvae shedding animal in the herd was used to define lungworm positive farms. On average, at least 30% of the herd had to be seropositive before the BTM ELISA was found positive for lungworm antibodies. Results indicate that the BTM ELISA in its current form does not appear to be suitable for surveys on the prevalence of lungworm presence on farms. However, this BTM ELISA might be used in large-scale surveys to detect, for instance, annual changes in percentage positive farms, as long as it is recognized that positivity is more closely related to incidence of lungworm disease than to prevalence of lungworm infection.  相似文献   
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Landscape Ecology - Plant populations in agricultural landscapes are mostly fragmented and their functional connectivity often depends on seed and pollen dispersal by animals. However, little is...  相似文献   
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The severity of diarrhoea and the degree of hyperaemia of the conjunctiva and nose were recorded in veal calves being fattened on either cows milk or milk-replacer. A skin-prick test using the milk-replacer as antigen was also performed. Control calves received only their mother's milk. Among these control calves there were no abnormalities, and in the calves fed other cows milk only slight abnormalities were seen. In contrast, in the calves fattened on milk-replacer, and especially in the calves showing the 'cachexia' syndrome, there were moderate to severe abnormalities and clear correlations were found between the severity of the diarrhoea and the hyperaemia of the conjunctiva and nose, and the scores recorded in the skin-prick test.  相似文献   
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Lactating Holstein-Friesian dairy cows in four separately housed groups in a herd with endemic digital dermatitis (DD) were monitored weekly for 4 weeks in December 2004 for the presence of and transition between five stages (M0-M4) of DD. Cows were also monitored for the presence of heel horn erosion (HHE) and interdigital hyperplasia. Prior to the study, two groups had been housed indoors on a high or low energy ration, one group had been grazed and one was a dry cow group. All cows received the same ration during the period of investigation. 'Active infection' was defined as transition from M0, M1, M3 or M4 to M2 and 'resolving M2 lesions' were defined as transition from M2 to another stage. M2 lesions were diagnosed on 106 occasions in the hind claws of 49 (36%) of 138 dairy cows; both hind claws were affected in nine cases (18%). M2 lesions were more often painful on palpation than other stages; 94% of M2 lesions were located plantar-medially near the interdigital cleft and 71% had a diameter of 2-4 cm. More M1 lesions than other stages were found within the interdigital space. When interdigital hyperplasia was present, claws were always concurrently affected by DD. The baseline incidence for 'active infection' was 6% per week, increasing to 11% when HHE was present, 14% when cows were previously housed indoors and fed a high energy ration and 16% when cows were 60-120 days in lactation. Topical treatment with chlortetracycline resulted in resolution from M2 of 79% per week. There were no significant effects of group, stage of lactation, parity or HHE on resolution of M2 lesions.  相似文献   
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