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Compressed wooden plates and dowels were used to connect members in post-and-beam structures as a substitute for a steel fastener.
In order to take advantage of the characteristic properties of compressed wood and to achieve optimum joint performance, two
compressed wooden plates were used in each joint to give multiple shear planes for each compressed wooden dowel. Consequently,
this type of joint showed very good properties in pull-out and momen-trotation performance, and its engineering design could
be further optimized. This joint is expected to be introduced to many kinds of structural systems, including long-span frame
structures made of domestic timber found in Japanese residential houses. 相似文献
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Kang MR Kim HM Kang JS Lee K Lee SD Hyun DH In MJ Park SK Kim DC 《Plant foods for human nutrition (Dordrecht, Netherlands)》2011,66(2):101-106
This study was performed to elucidate the anticancer mechanism of a lipid-soluble ginseng extract (LSGE) by analyzing induction
of apoptosis and arrest of cell cycle progression using the NCI-H460 human lung cancer cell line. Proliferation of NCI-H460
cells was potently inhibited by LSGE in a dose-dependent manner. The cell cycle arrest at the G0/G1 phase in NCI-H460 cells
was induced by LSGE. The percentage of G0/G1 phase cells significantly increased, while that of S phase cells decreased after
treatment with LSGE. The expression levels of cyclin-dependent kinase2 (CDK2), CDK4, CDK6, cyclin D3 and cyclin E related
to G0/G1 cells progression were also altered by LSGE. In addition, LSGE-induced cell death occurred through apoptosis, which
was accompanied by increasing the activity of caspases including caspase-8, caspase-9 and caspase-3. Consistent with enhancement
of caspase activity, LSGE increased protein levels of cleaved caspase-3, caspase-8, caspase-9, and poly-ADP-ribose polymerase
(PARP). These apoptotic effects of LSGE were inhibited by the pan-caspase inhibitor Z-VAD-fmk. These findings indicate that
LSGE inhibits NCI-H460 human lung cancer cell growth by cell cycle arrest at the G0/G1 phase and induction of caspase-mediated
apoptosis. 相似文献
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Antibodies to Asp-Asp-Glu-Asp can inhibit transport of nuclear proteins into the nucleus 总被引:18,自引:0,他引:18
Y Yoneda N Imamoto-Sonobe Y Matsuoka R Iwamoto Y Kiho T Uchida 《Science (New York, N.Y.)》1988,242(4876):275-278
The signal sequence of simian virus 40 (SV40) large T-antigen for translocation into the nucleus is composed of positively charged amino acids Lys-Lys-Lys-Arg-Lys. Rabbit antibodies to a synthetic peptide containing the negatively charged amino acid sequence Asp-Asp-Asp-Glu-Asp were obtained. Indirect immunofluorescence of the antigens recognized by the antibody was punctate at the nuclear rim or the nuclear surface, depending on the plane of focus. The antibody blocked transport of nuclear proteins into the nucleus. The antigens recognized by the antibody were predominantly localized to the nuclear pores. 相似文献
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Motohiko Kondo Hideo Maeda Akitoshi Goto Hiroshi Nakano Nobuharu Kiho Tomoyuki Makino 《Soil Science and Plant Nutrition》2013,59(1):133-143
Pot and field experiments were conducted to clarify the effect of soil exchangeable potassium (K) and cesium-137 (137Cs) on 137Cs accumulation and to establish soil index in rice (Oryza sativa L.). Four paddy soils in Fukushima Prefecture, Japan, showing different transfer factors for radioactive Cs derived from the accident of Fukushima Daiichi Nuclear Power Station in the field were compared in terms of 137Cs accumulation in rice in a pot experiment. 137Cs accumulation in shoots and brown rice widely varied among soils with the transfer factor ranging from 0.018 to 0.068 for shoots and 0.004 to 0.065 for brown rice. 137Cs concentration in brown rice and shoots tended to decrease with higher levels of soil exchangeable K, and they were more closely related to the exchangeable Cs/K ratio. Similar relationships between the Cs/K ratio and Cs accumulation in plants were obtained for the stable isotope cesium-133 (133Cs). The distributions of 137Cs and 133Cs in grains were also similar and variable among soils. The transfer factors obtained in pot experiments mostly agreed with field observations. The results imply that the exchangeable 137Cs/K can be a potential soil index to estimate 137Cs accumulation in rice. 相似文献
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In the present study, a plate and a doweled fastener made of compressed wood (CW) were newly introduced into a moment resisting
column-beam joint system for a small portal frame structure. A mechanical model that contains not only an axial spring, but
also a rotational spring, considered resistant factors to verify how each element resists rotation. Theoretical performance
was compared with experimental data. Consequently, the mechanical model was shown to be suitable and the combination of resisting
factors was found to be very effective; i.e., the rotational spring provides more influence on the stiffness and moment compared
with the axial spring. Large moment and ductility can be achieved by virtue of the high embedding performance of the CW plate
in the rotational spring, accompanied with the high shearing performance of the CW dowel in the axial spring. 相似文献
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Tomohito Arao Tomoyuki Makino Akira Kawasaki Ikuko Akahane Nobuharu Kiho 《Soil Science and Plant Nutrition》2018,64(3):433-437
ABSTRACTHigh air temperatures during the grain-filling stage of rice (Oryza sativa L.) decrease grain yield and quality. Temperatures above the optimal growth temperature impair dry matter production due to reduced grain size. Since the arsenic (As) concentration in grain is determined by the As accumulation and the grain weight, we focused on the effect of air temperature before and after rice heading on the As concentration in grain. Rice plants have been planted in the same field every year since 1974 with a similar set-up and water management. We analyzed the As concentrations in stored rice grains produced in 1995–2014 and evaluated the possible relationships with the meteorological data for the associated production year. The average daily mean air temperatures (DMTs) from 2 weeks after the heading day to 4 weeks after the heading day were significantly correlated with the inorganic As concentrations in the grains, whereas there was no significant correlation between the grain As concentration and the average DMT during 1 week after the heading day or 3 weeks before the heading day. These findings indicate that high air temperature is more effective at increasing As in grain in the late ripening stage of rice than before the ripening stage or in the early ripening stage. Further experiments are necessary to clarify why As concentrations in grain increase when high air temperatures occur in the late ripening stage of rice. 相似文献
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