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1.
Gonadotrophin-releasing hormone treatment in cattle: a meta-analysis of the effects on conception at the time of insemination 总被引:1,自引:0,他引:1
SUMMARY Data from 40 trials described in 27 published papers were analysed by meta-analysis (pooling of data from numerous trials into a single analysis) to evaluate the effects of injecting gonadotrophin-releasing hormone (GnRH) In cattle at the time of Insemination on the risk of pregnancy. A total of 19 019 cows were involved In these studies. Analyses were stratified by trial and by the effects of dose of GnRH, type of GnRH and Insemination number (first, second or third and greater). Mantel-Haenszel analysis revealed that use of GnRH at Insemination significantly Increased the overall risk of pregnancy by 12.5% In treated cows (P < 0.05). However, Increases In risk of pregnancy were greatest (22.5%) when repeat breeders were treated. Results for use of GnRH or analogue at first service were similar, with Increased risks of pregnancy in treated cows of 5.2 and 8.0%, respectively. The risk of pregnancy tended to be higher (11.1%) when the dose of GnRH was 250 μg and when used at second Insemination (9.9%). The analyses demonstrated that while treatment at Insemination with GnRH and GnRH analogues Increased conception rates In dairy cattle, some variation In study results was attributable to the number of Inseminations after calving at which GnRH Is administered. Further efforts should be made to determine characteristics of populations of cows that have good fertility responses to GnRH and to determine the mode of action of GnRH in Increasing fertility. Meta-analysis proved to be a useful technique for evaluating the apparently conflicting results from trials and in evaluating the effect of factors such as Insemination number, dose and type of GnRH on responses to treatment. 相似文献
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对猪轮状病毒2型(PCV2)的研究,为全球探讨断奶后多系统消瘦综合征(PMWS)的特殊问题,提供了许多答案。但是本文提出了一些还需要特别注意的地方 ,用以避免其可能导致的“恶果”出现。过去几年里 ,在关于断奶后多系统消瘦综合征(PMWS)、猪轮状病毒病(PCVD )全球性的探讨中 ,已经对许多关于疾病流行特点的来源和特征进行了广泛的研究。猪血清中猪轮状病毒2型 (PCV2)抗体以及猪的组织样本的检测表明 ,至少从1969年起 ,猪轮状病毒2型 (PCV2)的抗体就已经存在于猪的群体中了。现在已经确定 ,从1986年起在西班牙和英国就发现了传统的PMWS… 相似文献
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Ⅱ型猪环状病毒 (PCV2 )现已被证明是断奶后全身消耗性综合征 (PMWS)的致病因子 ,这一综合征是一种可造成世界各地严重经济损失的猪病。最近的研究还证实此病毒与加拿大和欧洲猪群的繁殖障碍有关。但是 ,绝大多数PCV2感染都是亚临床性的。刺激仔猪免疫系统是感染此病毒后产生临床疾病的重要因子吗 ? 相似文献
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对Ⅱ型猪圆环病毒的研究为与猪断奶后多系统消耗性综合征在全球爆发有关的问题提供了大量答案,但还有一些方面迫切需要引起人们的关注,以便为可能出现的梦魇般的前景准备对策. 相似文献
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Examination of 25 cases of multiple benzimidazole and levamisole resistance, identified in sheep by faecal egg count reduction testing at the Batchelar, Lincoln and Invermay Animal Health Laboratories, showed that benzimidazole-levamisole combinations provided effective control in eight (47%) of 17 cases in which they were tested. Overall, the use of combination drenches resulted in average improvements in faecal egg count reductions of 25.6% (p<0.01) and 23.2% (p<0.05), respectively, over those achieved by the use of benzimidazole or levamisole drenches alone. The results suggest that instances of multiple resistance in which combination drenches might be effective are unlikely to be predictable either by identification of the parasites involved, or from the levels of benzimidazole or levamisole resistance present. 相似文献
7.
Parainfluenza-3 (Pi3) virus infection in a group of 25 calves is described. The virus was isolated from the lungs of four calve at days 6, 7, 13 and 55 after they were housed together at birth. Intracytoplasmic inclusion bodies were seen by light microscopy in bronchial and bronchiolar epithelial cells of two of these calves. Virus infected cells were detected by electron microscopy in three of the four calves. Haemagglutination inhibition antibodies to Pi3 virus were found in the sera of the calves. Despite the virus being present in the group from one week, a significant increase in antibody titre was found in only two animals although all the calves were in contact with each other during the study period. The pulmonary lesions in the four infected calves consisted of a bronchitis and bronchiolitis with infiltration of the walls and lumena of these structures by neutrophils and an adjacent neutrophil infiltration of alveoli some of which were collapsed. 相似文献
8.
Following an antigenic dose of 10 microgram or a tolerogenic dose of 200 microgram of Escherichia coli O138 lipopolysaccharide (LPS), BALB/c mice were examined on day 14 for percentages of theta-bearing cells. A considerable increase in T cells was noticed in lymphocytes from tolerant draining lymph nodes, and furthermore these cells did not possess receptors for LPS when tested for rosette inhibition. However, when the supernatant from 1 X 10(7) macrophages, pretreated with 150 microgram LPS, was given to tolerant mice on day 7, by day 14 tolerance was found to be broken, anti-LPS IgG was present in circulation and the draining lymph node contained T cells specifically committed to LPS. The change from suppressor to helper T cell activity is discussed in relation to enhancement of the immune response. 相似文献
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