排序方式: 共有3条查询结果,搜索用时 15 毫秒
1
1.
Sjolund M. Jennifer Arnsdorf Yvonne M. Carnegie Mairi Fornefeld Eva Will Torsten 《植物病害和植物保护杂志》2019,126(1):89-92
Journal of Plant Diseases and Protection - Psyllids are small, phloem-feeding insects. Several species are vectors of economically important pathogens, such as ‘Candidatus Liberibacter... 相似文献
2.
Atomic force microscopy and dissection of gap junctions 总被引:16,自引:0,他引:16
An atomic force microscope (AFM) was used to study the structure of isolated hepatic gap junctions in phosphate-buffered saline (PBS). The thickness of these gap junctions appears to be 14.4 nanometers, close to the dimensions reported by electron microscopy (EM). When an increasing force is applied to the microscope tip, the top membrane of the gap junction can be "dissected" away, leaving the extracellular domains of the bottom membrane exposed. When such "force dissection" is performed on samples both trypsinized and fixed with glutaraldehyde, the hexagonal array of gap junction hemichannels is revealed, with a center-to-center spacing of 9.1 nanometers. 相似文献
3.
Nucleated conformational conversion and the replication of conformational information by a prion determinant 总被引:2,自引:0,他引:2
Serio TR Cashikar AG Kowal AS Sawicki GJ Moslehi JJ Serpell L Arnsdorf MF Lindquist SL 《Science (New York, N.Y.)》2000,289(5483):1317-1321
Prion proteins can serve as genetic elements by adopting distinct physical and functional states that are self-perpetuating and heritable. The critical region of one prion protein, Sup35, is initially unstructured in solution and then forms self-seeded amyloid fibers. We examined in vitro the mechanism by which this state is attained and replicated. Structurally fluid oligomeric complexes appear to be crucial intermediates in de novo amyloid nucleus formation. Rapid assembly ensues when these complexes conformationally convert upon association with nuclei. This model for replicating protein-based genetic information, nucleated conformational conversion, may be applicable to other protein assembly processes. 相似文献
1