Serological responses of specific pathogen-free foals to equine herpesvirus-1: primary and secondary infection, and reactivation.     

J S Gibson  T O'Neill  A Thackray  D Hannant  H J Field 《Veterinary microbiology》1992,32(3-4):199-214

Serum antibody (virus neutralisation, complement fixation, IgM and IgG) responses to equine herpesvirus-1 (EHV-1) infection were measured in six foals which were initially free from EHV-1 and EHV-4 infection and maternally-derived antibodies. Following primary infection, high titres of virus neutralisation and complement fixation antibodies were detectable against EHV-1, however, corresponding antibody levels against EHV-4 were low or inapparent, although the two viruses share a number of cross-reactive epitopes. In addition, following the primary infection with EHV-1, IgM levels increased before those of IgG, virus neutralisation and complement fixation antibodies, peaked sooner and thereafter declined. Stimulation of IgM levels was observed on secondary infection with EHV-1 given 61 days later. In contrast, IgG, virus neutralisation and complement fixation antibodies following primary infection were more sustained and no increase in their levels was observed on secondary infection. No consistent changes in IgM or IgG levels were seen after administration of dexamethasone to reactivate latent virus.  相似文献   

Sensitivity,specificity, and predictive values of reagent test strip estimations of blood urea nitrogen     

Hill D  Correa MT  Stevens JB 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1994,23(3):73-75

Azostix-reagent-tests(R) strips (Ames, Miles, Inc., Diagnostic Division, Elkhart, IN) were used to measure blood urea nitrogen values in blood samples from 125 dogs and cats at the North Carolina State University, College of Veterinary Medicine. Results of the tests were compared with standard serum urea nitrogen results. Sensitivity, specificity, and negative predictive values were high (86.4, 90.3, and 96.5%, respectively). Positive predictive value was low, 65.5% of the dogs and cats with elevated blood urea nitrogen values were correctly classified as abnormal The test performs well when the prevalence of abnormal values is near 50%.  相似文献   

Bovine ceroid-lipofuscinosis: pathology of blindness     

Jolly RD  Gibson AJ  Healy PJ  Slack PM  Birtles MJ 《New Zealand veterinary journal》1992,40(3):107-111

Five Devon cattle with suspected ceroid-lipofuscinosis and aged between 19 and 39 months of age were humanely slaughtered and subjected to post-mortem examination. There was severe atrophy of the cerebrum, particularly of the occipital cortex. Microscopy also showed severe atrophy of the retina with complete loss of photoreceptor cells, even in the youngest animal examined. Histopathologically the disease was characterised by accumulation of a fluorescent lipopigment in neurones, including those of the retina and a severe astrocytosis. The disease, which is characterised by the accumulation of subunit c of mitochondrial ATP synthase, is similar to that extensively described in South Hampshire sheep except that the retinal lesions were more severe. In contrast, tremors were not noted in the cattle. The clinical history and similarity to the disease in sheep and other species indicated inheritance was as an autosomal recessive trait.  相似文献   

Evaluation of a radioimmunoassay for type III procollagen peptide in the dog     

Dimski DS  Brooks CL  Johnson SE 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1990,19(2):40-44

Type III procollagen peptide (P-3-P) is a serum marker for hepatic fibrosis in humans. The utility of a commercially available radioimmunoassay for P-3-P was evaluated in the dog. The specificity of the assay was assessed by polyacrylamide gel electrophoresis (PAGE) of canine serum and purified bovine P-3-P, followed by Western immunoblotting with rabbit aniti-P-3-P serum. The sensitivity was assessed by performing the radioimmunoassay on dilutions of sera from 22 dogs. Polyacrylamide gel electrophoresis of purified bovine P-3-P and sera from two dogs suspected of having elevated P-3-P concentrations revealed no homologous bands of staining. Western immunoblotting showed marked cross-reactivity of the high antisera concentrations with several components of the serum proteins, but none corresponding to the purified P-3-P. All tested sera from dogs had minimal competitive binding with radiolabeled P-3-P in the radioimmunoassay. Dilution curves of dog sera did not parallel either the standard curve or the dilution curve of a known test human serum. There were no statistically different P-3-P concentrations in any of the groups of dogs studied. It was concluded that currently available radioimmunoassay kits for the measurement of P-3-P in the human are not applicable in the dog. Seemingly, the structure or metabolism of canine P-3-P may vary significantly from that of the bovine or human, limiting the sensitivity and specificity of this assay in the dog.  相似文献   

The "barker" (neonatal respiratory distress) syndrome in the pig: its occurrence in the field.     

E A Gibson  R J Blackmore  W V Wijeratne  A E Wrathall 《The Veterinary record》1976,98(24):476-479

A new syndrome, characterised by acute respiratory distress and by abnormalities of the skin, hair and thyroid, was the apparent cause of neonatal death in 35 (24 per cent) of 146 piglets sired by a large white boar in four small commercial pig units. The syndrome appears to be of genetic origin, inherited as an autosomal recessive trait. Its similarities with the respiratory distress syndrome (RDS) of the newborn infant and the "barker" syndrome of the newborn foal are discussed.  相似文献   

A retrospective study of feline trauma patients admitted to a referral centre          下载免费PDF全文

T. Hernon  M. Gurney  S. Gibson 《The Journal of small animal practice》2018,59(4):243-247

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Some behavioural and ecological factors affecting distribution,biomass and production of juvenile Atlantic salmon          下载免费PDF全文

R. John Gibson 《Ecology of Freshwater Fish》2015,24(3):397-411

Observations were made in an experimental stream tank (total area 14.7 m²) on juvenile Atlantic salmon, Salmo salar L (parr), relating experimental observations to field observations, including the reported diurnal fasting behaviour of juvenile salmon at water temperatures <10 °C. Densities in the tank ranged from five to twenty parr, at water temperatures ranging from 4.6 °C to 15.8 °C. The wide channel of the stream tank, with mean water velocity of 18.8 cm·s^?1, was the preferred section, where territorial behaviour was observed. Biomass was regulated in the wide channel by territorial mosaics or by dominance hierarchies. Dominance hierarchies were reflected in coloration of the fish. Dominant salmon were generally in the wide channel. Densities of salmon parr (of mean fork length 10.2 cm) in the channel ranged from 0.84 m^?2 to 1.73 m^?2, with an average biomass of 14.2 g·m^?2. Growth was least at the 5.9 °C temperature treatment. In experiments at temperatures below 10 °C, feeding, dominance hierarchy and territorial behaviour were observed in daylight hours, contrary to the published literature. Interactions with other species may affect behaviour. Some observations were made on a closely related species, brown trout (Salmo trutta L.), a commonly cohabiting species in many systems. Trout displaced salmon from their preferred locations in the tank and were more aggressive than the salmon, reducing agonistic behaviour by the salmon. The commonest agonistic act shown by salmon was ‘charge’ and that by the trout was ‘approach’. Some field observations affecting behaviour and production are discussed.  相似文献   

Biofilm‐Associated Gene Expression in Staphylococcus pseudintermedius on a Variety of Implant Materials          下载免费PDF全文

Evan C. Crawford  Ameet Singh  Thomas W.G. Gibson  J. Scott Weese 《Veterinary surgery : VS》2016,45(4):499-506

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Evaluation of cross-protection afforded by a Salmonella Choleraesuis vaccine against Salmonella infections in pigs under field conditions     

Maes D  Gibson K  Trigo E  Saszak A  Grass J  Carlson A  Blaha T 《Berliner und Münchener tier?rztliche Wochenschrift》2001,114(9-10):339-341

This field study investigated the efficacy of a Salmonella Choleraesuis live vaccine (Argus SC) to reduce the number of infections with Salmonella. Twelve groups of about 380 pigs each were randomly allocated to either vaccination (V) or no vaccination (C). The vaccine was applied orally at 3 and 16 weeks. Forty pigs per group were blood sampled at 3, 10, 16, and 24 weeks to detect possible antibodies against Salmonella. The prevalence of Salmonella in the lymph nodes was the major variable. In the V groups, only 0.6% of the lymph nodes were positive, whereas 7.2% were positive in the C groups (p < 0.001). The percentage of seropositive pigs at 24 weeks (cut-off OD > 10) was 26% and 9% in the V and C groups, respectively (p < 0.001). The present study documented that vaccination with a live modified S. Choleraesuis vaccine is a useful tool to lower the prevalence of Salmonella in swine herds.  相似文献   

Molecular surveillance of the incidence of Taylorella equigenitalis and Pseudomonas aeruginosa from horses in Ireland by sequence-specific PCR     

Moore JE  Buckley TC  Millar BC  Gibson P  Cannon G  Egan C  Cosgrove H  Stanbridge S  Anzai T  Matsuda M  Murphy PG 《Equine veterinary journal》2001,33(3):319-322

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