Dinoseb toxicosis in two dogs     

J D Fikes  R A Lovell  M Metzler  W B Buck 《Journal of the American Veterinary Medical Association》1989,194(4):543-544

Two male English Setters were noticed to be breathing rapidly, hyperexcitable, and atactic after roaming a rural area for 2 hours. Both dogs' cost were stained with yellow liquid. One dog died while en route to the veterinarian. Treatment was begun for the surviving dog for what was initially diagnosed to be organophosphorus or carbamate insecticide toxicosis. Before the diagnosis could be confirmed, the second dog died. The yellow liquid on the dogs' skin was identified as dinoseb in high concentrations. Dinoseb is an acutely toxic, substituted dinitrophenolic herbicide believed to act as an uncoupler of electron transport from oxidative phosphorylation.  相似文献   

Ocular pathology of caprine beta-mannosidosis     

J A Render  K L Lovell  M Z Jones  C A Wheeler 《Veterinary pathology》1989,26(5):444-446

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Gossypol toxicity in preruminant calves     

RZ ZELSKI  JT ROTHWELL†  RE MOORE‡  DJ KENNEDY§ 《Australian veterinary journal》1995,72(10):394-398

SUMMARY Twenty-four of 57 calves fed a diet containing 33% cotton seed meal (CSM) died between 7 and 15 weeks of age. Initial deaths were not accompanied by premonitory signs, but after CSM withdrawal most calves developed rough coats, anorexia, weakness, ascites and subcutaneous oedema. Those that died had large volumes of serous fluid in the body cavities, hard livers of ‘nutmeg’ appearance, and pulmonary congestion. Histopathologically the livers showed periacinar necrosis in acute cases and periacinar fibrosis in chronic cases. Lungs from several calves had oedema, haemosiderosis and fibrosis in some pulmonary vessels. Atrophy of myocardial fibres was present in most cases. The concentration of free gossypol in the diet was 100 to 220 mg/kg. Ante-mortem and post-mortem findings supported a diagnosis of gossypol poisoning. The deaths continued for 4 weeks after withdrawal of CSM from the diet.  相似文献   

A perspective on the measurement of time in plant disease epidemiology   总被引：2，自引：1，他引：2  

D. J. Lovell †  S. J. Powers  S. J. Welham  S. R. Parker 《Plant pathology》2004,53(6):705-712

The growth and development of plant pathogens and their hosts generally respond strongly to the temperature of their environment. However, most studies of plant pathology record pathogen/host measurements against physical time (e.g. hours or days) rather than thermal time (e.g. degree-days or degree-hours). This confounds the comparison of epidemiological measurements across experiments and limits the value of the scientific literature.  相似文献   

Letters     

Lovell WS 《Science (New York, N.Y.)》1971,171(3972):630-631

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Acute cortisol responses of calves to scoop dehorning using local anaesthesia and/or cautery of the wound   总被引：1，自引：0，他引：1  

SP SYLVESTER  DJ MELLOR  KJ STAFFORD  RA BRUCE  RN WARD 《Australian veterinary journal》1998,76(2):118-122

Objective To measure plasma cortisol responses in calves dehorned using a scoop after administration of local anaesthesia and/or cautery of the wounds.
Design A physiological study with controls.
Procedure There were six treatments: control handling with and without local anaesthesia, dehorning, dehorning after local anaesthesia, dehorning followed by wound cautery, and dehorning after local anaesthesia followed by wound cautery. Blood samples were taken before and after dehorning.
Results Dehorning caused an increase in plasma cortisol concentrations, which decreased a little to plateau values and then declined to pretreatment values 3 to 4 h after dehorning. The peak was smaller after local anaesthesia was administered but when its effects wore off, cortisol concentrations increased and thereafter were similar to those in the dehorned animals. The combination of local anaesthesia and cautery resulted in a plasma cortisol response similar to those in control calves with or without local anaesthesia.
Conclusions If plasma cortisol concentrations reflect the distress being experienced by the calves, then local anaesthesia reduces the acute distress for about 3 h after dehorning but not during the subsequent 3 to 4 h. Combining local anaesthetic and cautery prevented the significant increase in plasma cortisol following dehorning and may eliminate the acute distress caused by scoop dehorning.  相似文献   

Essential Fatty Acid Supplementation In The Treatment Of Canine Atopy: A Preliminary Study     

David H.  Lloyd Lovell R.  Thomsett 《Veterinary dermatology》1990,1(1):41-44

Abstract— In an open, uncontrolled study, 10 dogs with atopy were given evening primrose oil (EPO) (5ml/10kg/day) over a period of 9 weeks. During the first three weeks pruritus, scaling and oedema worsened but erythema and coat condition tended to improve. Subsequently all these parameters tended to improve. The effect on oedema was significant (p < 0.05). Eight of these dogs and two others were then given a 4:1 mixture of EPO and marine fish oil for 9 weeks. Although further reductions in scale and improvements in coat condition were marked in some animals, no significant changes occurred. Alterations in the plasma phospholipid essential fatty acid levels reflected the compositions of the two supplements. These findings suggest that EPO can ameliorate of atopy in dogs. This mirrors observations obtained in studies of human atopic eczema. Résumé— Dans une étude ouverte, sans lot témoin, 10 chiens souffrant d'atopie ont reçu de l'huile d'onagre (5 ml/10 kg/jour) pendant une période de 9 semaines. Pendant les 3 premières semaines, le prurit, le squamosis et l'oedème se sont aggravés mais, l'érythème et l'aspect du poil tendaient à s'améliorer. Enfin tous ces parametres tendaient à s'améliorer. L'effet sur l'érythème a été significatif (p < 0.05). Huit de ces chiens et deux autres ont alors reçu un mélange (4:1) d'huile d'onagre et d'huile de poisson de mer pendant 9 semaines. Bien qu'ultérieurement la diminution du squamosis et l'amélioration de l'état de la fourrure aient été manifestes chez certains animaux, il n'y eut pas de changement significatif. Les modifications des taux d'acides gras essentiels des phospholipides plasmatiques ont reflété la composition des deux supplémentations. Ces observations suggèrent que l'huile d'onagre peut apporter une amélioration de l'atopie canine. Cela reflète certains résultats observés lors d'études sur l'eczéma atopique de l'homme. Zusammenfassung— In einer offenen, nicht kontrollierten Untersuchung wurde 10 Hunden mit Atopie Nachtkerzenöl (EPO) in einer Dosierung von 5 ml/10 kg/Tag über einen Zeitraum von 9 Wochen verabreicht. Während der ersten 3 Wochen verschlimmerten sich Pruritus, Schuppenbildung und Ödeme, während Erytheme und Fellzustand eher eine Tendenz zur Besserung zeigten. Danach besserten sich alle diese Parameter. Die Wirkung auf Erytheme war signifikant (p < 0.05). Acht dieser Hunde und zwei andere erhielten 9 Wochen lang Nachtkerzenöl und Seefischöl in einer Mischung von 4:1 im Anschlufl an diese Untersuchung. Obwohl eine weitere Verminderung der Schuppenbildung und eine Vorbesserung der Fellqualität bei einigen Tieren festgestellt wurden, waren diese Veränderungen nicht signifikant. Die Veränderungen der essentiellen phospholipiden Fettsäuren im Plasma spiegeln die Zusammensetzung der beiden verabreichten Öle wieder. Diese Befunde weisen darauf hin, daß die Atopie des Hundes durch EPO gebessert werden kann. Dies entspricht auch Beobachtungen bei Untersuchungen des atopischen Exzems des Menschen.  相似文献   

Exercise physiology. An overview     

D K Lovell 《Veterinary Clinics of North America: Equine Practice》1985,1(3):439-445

Through the study of equine exercise physiology, one can learn more about what happens to the body of the performance horse during all forms of exercise. Better understanding of skeletal, joint, tendon, and ligament adaptations to loading and stress may allow adjustments to be made in training techniques to reduce the incidence of injury. The information obtained from exercise research may also facilitate the investigation of questions such as the following: What makes one horse perform better than another? How can one bring out the optimal performance in each horse? How can one tell when a horse has arrived at its peak performance capability? What are the factors that actually limit performance?  相似文献   

Effect of Initial GnRH and Duration of Progesterone Insert Treatment on the Fertility of Lactating Dairy Cows          下载免费PDF全文

MG Colazo  DJ Ambrose 《Reproduction in domestic animals》2015,50(3):497-504

The study compared response to prostaglandin F2α (PG), synchrony of ovulation and pregnancy per AI (P/AI) in a 5‐ vs a 7‐day Ovsynch + PRID protocol and investigated whether the initial GnRH affects P/AI in lactating dairy cows. Two hundred and seventy‐six cows (500 inseminations) were assigned to one of four timed‐AI (TAI) protocols: (i) PRID‐7G; 100 μg GnRH im, and a progesterone‐releasing intravaginal device (PRID) for 7 days. At PRID removal, PG (500 μg of cloprostenol) was given im. Cows received the second GnRH treatment at 60 h after PRID removal and TAI 12 h later. (ii) PRID‐5G; as PRID‐7G except the duration of PRID, treatment was 5 days and PG was given twice (12 h apart). (iii) PRID‐7NoG; as PRID‐7G except the initial GnRH, treatment was omitted. (iv) PRID‐5NoG; as PRID‐7NoG except the duration of PRID, treatment was 5 days. Response to treatments and pregnancy status at 32 and 60 days after TAI was determined by ultrasonography. The percentage of cows ovulating before TAI was greatest in PRID‐7G (17.1%), and the percentage of cows that did not have luteal regression was greatest in PRID‐5G (9.5%). The overall P/AI at 32 and 60 days did not differ among TAI protocols. However, during resynchronization, cows subjected to the 5‐day protocols had greater (p < 0.05) P/AI (45.3% vs 33.6%) than cows subjected to the 7‐day protocols. Pregnancy loss between 32 and 60 days tended (p = 0.10) to be greater in cows that did not receive initial GnRH (14.8%) compared to those that received GnRH (8.2%). In conclusion, the PRID‐5G protocol resulted in fewer cows responding to PG, but P/AI did not differ among TAI protocols. A 5‐day protocol resulted in more P/AI in resynchronized cows, and cows that did not receive initial GnRH tended to experience more pregnancy losses.  相似文献   

The effect of footrot on body weight and wool growth of sheep   总被引：1，自引：0，他引：1  

DJ MARSHALL  RI WALKER  BR CULLIS  MF LUFF 《Australian veterinary journal》1991,68(2):45-49

Body weight and traits associated with production of wool were measured over a 2-year period between 1985 and 1987 in south-western New South Wales in a flock of Merino wethers experimentally infected with footrot. The disease was allowed to spread freely amongst 150 of the flock but kept at very low prevalence in the remaining 50 by preventive footbathing during transmission periods. Severe, underrunning footrot had a significant adverse effect on body weight, for each year of the trial. Body weight was most severely reduced at times of the year when footrot was spreading among animals and lesions were severe. The mean body weight of the infected group at the end of the 2 years of observation was 7.3 kg (11.6%) below that of the control group. Footrot also depressed wool growth, with the mean clean fleece weight of the infected group being 0.4 kg (8%) lighter than that of the controls at each of the 2 annual shearings. There were no consistent differences between the groups for the other wool characteristics measured.  相似文献