Aerosol therapy in the equine species     

D.H. Duvivier  D. Votion  S. Vandenput  P. Lekeux 《Veterinary journal (London, England : 1997)》1997,154(3):189-202

Inhalation therapy plays an increasing role in the management of equine respiratory disorders. Thisalternative to systematic treatment permits a high concentration of medication to act locally while minimizing side effects and residues. In human medicine, literature in this field is prolific and continuously renewed, whereas in veterinary medicine, applications of aerosol therapy are less extensive. This review considers the principles of action of the different types of devices used for inhalation, i.e., nebulization, metered-dose inhalation and dry powder inhalation, describes the technical and practical requirements for their use in the equine species and considers the advantages and disadvantages of each inhalation device. The pharmacological agents currently administered to horses by inhalation are also discussed. Perspectives of aerosol therapy in the equine species, including aerosols already used in human medicine and their potential applications for horses are described.  相似文献   

In vitro susceptibility of Brachyspira hyodysenteriae to organic acids and essential oil components     

Lien VANDE MAELE  Marc HEYNDRICKX  Dominiek MAES  Nele DE PAUW  Maxime MAHU  Marc VERLINDEN  Freddy HAESEBROUCK  An MARTEL  Frank PASMANS  Filip BOYEN 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2016,78(2):325-328

The antibacterial potential of organic acids and essential oil components against Brachyspira hyodysenteriae, the causative pathogen of swine dysentery, was evaluated. Minimum inhibitory concentrations (MIC) of 15 compounds were determined at pH 7.2 and pH 6.0, using a broth microdilution assay. In addition, possible synergism was determined. MIC values for the three tested strains were similar. For organic acids, MIC values at pH 6.0 were lower than at pH 7.2. B. hyodysenteriae was most sensitive to cinnamaldehyde and lauric acid, with MIC values <1.5 mM. Most antibacterial effects of binary combinations were additive, however, for thymol and carvacrol, synergism could be observed. In vitro results demonstrate the antibacterial action of certain essential oil components and organic acids against B. hyodysenteriae.  相似文献   

Planning wetland protection and restoration for the safeguard of ecosystem service flows to beneficiaries     

Goyette  Jean-Olivier  Cimon-Morin  Jérôme  Mendes  Poliana  Thériault  Maxime  Pellerin  Stéphanie  Poulin  Monique 《Landscape Ecology》2021,36(9):2691-2706

Landscape Ecology - Human activities have led to the degradation of wetlands, impinging on their capacity to deliver essential ecosystem services to society. Wetland restoration now appears an...  相似文献   

Evaluation of the durability of the <Emphasis Type="Italic">Barley yellow dwarf virus</Emphasis>-resistant <Emphasis Type="Italic">Zhong ZH</Emphasis> and <Emphasis Type="Italic">TC14</Emphasis> wheat lines     

Florian Chain  Gérard Riault  Maxime Trottet  Emmanuel Jacquot 《European journal of plant pathology / European Foundation for Plant Pathology》2007,117(1):35-43

Serial passage experiments (SPE) of a Barley yellow dwarf virus-PAV (BYDV-PAV) isolate were performed on Zhong ZH and TC14 wheat lines to evaluate the durability of their resistance to BYDV. At different passage numbers (from the 2nd to the 114th), biological properties of the produced isolates were recorded either by monitoring infection percentages and virus titers of the first 3 weeks of viral infection or by measuring their impact on yield components. Statistical analyses using the area under pathogen progress curves and the area under concentration progress curves demonstrated that these two resistant lines induce, after only a few passages, a selection of variant(s) with significantly modified infection abilities. Isolates resulting from SPE performed on these lines induced important decreases of yield components. These results indicate that the use of Zhong ZH and TC14 lines in BYDV-resistant breeding programmes should be approached with caution.  相似文献   

Global parasite and Rattus rodent invasions: The consequences for rodent‐borne diseases          下载免费PDF全文

Serge MORAND  Frédéric BORDES  Hsuan‐Wien CHEN  Julien CLAUDE  Jean‐François COSSON  Maxime GALAN  Gábor Á CZIRJÁK  Alex D GREENWOOD  Alice LATINNE  Johan MICHAUX  Alexis RIBAS 《Integrative zoology》2015,10(5):409-423

We summarize the current knowledge on parasitism‐related invasion processes of the globally invasive Rattus lineages, originating from Asia, and how these invasions have impacted the local epidemiology of rodent‐borne diseases. Parasites play an important role in the invasion processes and successes of their hosts through multiple biological mechanisms such as “parasite release,” “immunocompetence advantage,” “biotic resistance” and “novel weapon.” Parasites may also greatly increase the impact of invasions by spillover of parasites and other pathogens, introduced with invasive hosts, into new hosts, potentially leading to novel emerging diseases. Another potential impact is the ability of the invader to amplify local parasites by spillback. In both cases, local fauna and humans may be exposed to new health risks, which may decrease biodiversity and potentially cause increases in human morbidity and mortality. Here we review the current knowledge on these processes and propose some research priorities.  相似文献   

Biochemistry. Zooming into live cells     

Pinaud F  Dahan M 《Science (New York, N.Y.)》2008,320(5873):187-188

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First case of pithomycotoxicosis (facial eczema) in the Netherlands     

van Wuijckhuise L  Snoep J  Cremers G  Duvivier A  Groeneveld A  Ottens W  van der Sar S 《Tijdschrift voor diergeneeskunde》2006,131(23):858-861

Between mid September and the beginning of November 2005, the Animal Health Service (AHS) received thirteen reports offarms on which several animals showed severe symptoms of solar eczema. Blood chemistry showed very high levels of GOT/AST and GGT indicative of severe liver damage. Farm visits to eight farms showed that the animals--previous to the start of the symptoms--had been grazing 24 hours/day and received no additional feed. Ingestion of poisonous plants or medications was considered unlikely to have caused the liver damage, and liver fluke infections were present on only two farms. Microscopic examination of specimens of grass revealed the presence of spores of Pithomyces chartarum in samples taken from six of nine farms. This fungus produces the mycotoxin sporidesmin, which causes severe liver damage and pithomycotoxicosis (facial eczema). This article is the first to describe Pithomyces chartarum in cattle in mainland Europe. Further research on the distribution and re-occurrence of Pithomyces chartarum infection and sporidesmin survival in grass silage is recommended.  相似文献   

Protozoal diseases in Europe     

Maxime Madder  Dirk Berkvens  Dirk Geysen  Agustin Estrada Pena 《Veterinary journal (London, England : 1997)》2013,195(2):137-138

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Reporting of items associated with study bias in veterinary research is poor     

Maxime Rufiange  Frédérik Rousseau-Blass  Daniel Pang 《Veterinary anaesthesia and analgesia》2018,45(6):885.e12-885.e13

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Breeding for insect resistance in oilseed rape: Challenges,current knowledge and perspectives          下载免费PDF全文

Maxime R. Hervé 《Plant Breeding》2018,137(1):27-34

Dealing with insect pests is one of the biggest challenges facing the cultivation of oilseed rape (Brassica napus, OSR). Insect pests are usually controlled using insecticides, but the increasing occurrence of insecticide‐resistant populations and the socio‐economic context argue against the sole use of these substances. Plant resistance is a classical and proven alternative crop protection strategy that is the basic tool of integrated pest management. However, no insect‐resistant OSR cultivar is currently available on the market. Here, I review some of the constraints that make phenotyping for insect resistance particularly challenging with OSR and give perspectives to develop this resistance. Some studies have proved that breeding OSR for insect resistance could be achieved, and three strategies have been considered: introducing resistance transgenes into the OSR genome, exploiting natural variation in resistance already present in B. napus and introgressing resistance from other brassicaceous species. The white mustard, Sinapis alba, seems a particularly promising source of resistance against most of the OSR insect pests.  相似文献