Characterisation of the serum cytokine profile in feline atopic skin syndrome     

Cheryl Vargo  Robert Gogal  James Barber  Michaela Austel  Frane Banovic 《Veterinary dermatology》2021,32(5):485-e133

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Validation of the Accutrend Plus point‐of‐care triglyceride analyzer in horses,ponies, and donkeys          下载免费PDF全文

Michaela C. Pongratz Dr. med vet  DECEIM  FVH  Hannah K. Junge Dr. med vet  Barbara Riond Dr. med vet  FVH  Colin C. Schwarzwald Dr. med vet  PhD  DACVIM  DECEIM 《Journal of Veterinary Emergency and Critical Care》2016,26(5):682-690

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Sebaceous adenitis in the Akita: clinical observations, histopathology and heredity   总被引：1，自引：1，他引：0  

Reichler IM  Hauser B  Schiller I  Dunstan RW  Credille KM  Binder H  Glaus T  Arnold S 《Veterinary dermatology》2001,12(5):243-253

Ninety-seven pure-bred Akitas were examined clinically and histologically for sebaceous adenitis. The diagnosis was established histologically in 23 Akitas by demonstrating an inflammatory reaction targeted against the sebaceous glands or a reduction in the number of glands. The clinical course of sebaceous adenitis in the Akita was similar to that seen in other breeds. The first skin lesions occurred mainly on the dorsal midline and ears. Compared with the Poodle, the age at first onset of the disease was more variable and the hair loss affected mainly the undercoat. The progression of sebaceous gland destruction varied between dogs and was not seen in all cases. Because bud-like sebaceous gland proliferation could be identified, it seems that regeneration of the sebaceous glands may occur. An autosomal recessive inheritance appears to be possible. Apart from a genetic background, immune-mediated factors possibly influence the onset and course of sebaceous adenitis.  相似文献   

Ocular Onchocerca infections in two dogs in western United States     

Eberhard ML  Ortega Y  Dial S  Schiller CA  Sears AW  Greiner E 《Veterinary parasitology》2000,90(4):333-338

Two dogs, one from California and one from Arizona, were found to have aberrant infections caused by filarial nematodes of the genus Onchocerca. In both cases, the parasites are localized in or near the eye. In one case the worm was located in the cornea and was surgically removed. In the second case, a very marked granulomatous reaction was induced in the retrobulbar space, mimicking an abscess. This eye was enucleated. The worms in both instances were female, and were gravid, i.e. contained microfilariae in utero, indicating that a male worm(s) had been present and mating had occurred. The exact identity of the species of Onchocerca responsible cannot be determined, although the features observed are most like Onchocerca lienalis of cattle. These cases represent the fourth and fifth such cases reported from the US, and are especially interesting because of the unusual location of the worms, the small number of recognized cases, and the similarity to a recent zoonotic human infection.  相似文献   

Phenotypic and histological expression of different genetic backgrounds in interactions between lettuce, wild Lactuca spp., L. sativa × L. serriola hybrids and Bremia lactucae     

Aleš Lebeda  Michaela Sedlářová  James Lynn  David A. C. Pink 《European journal of plant pathology / European Foundation for Plant Pathology》2006,115(4):431-441

Phenotypic and histological responses of cultivated lettuce (Lactuca sativa) and wild relatives L. saligna, L.␣virosa as well as interspecific crosses derived from L. sativa × L. serriola to two races of Bremia lactucae (CS2, CS9) were investigated. With the exception of L. sativa genotypes, all accessions and hybrids expressed incomplete or complete resistance to both pathogen races, with slight differences at seedling and adult plant stages, respectively. Histological features of the interactions (development of pathogen infection structures and host hypersensitive response to attempted infection) were studied on leaf discs 48 h after inoculation. Interactions with similar phenotypic expression of resistance were characterized by significant variation in rate of development of pathogen infection structures and hypersensitive reactions. Differences found within eight Lactuca spp. accessions and hybrids challenged by two distinct pathogen races are interpreted and discussed.  相似文献   

Surface Electromyography of the Vastus Lateralis,Biceps Femoris,and Gluteus Medius Muscle in Sound Dogs During Walking and Specific Physiotherapeutic Exercises          下载免费PDF全文

Katharina Breitfuss DVM  Michaela Franz DVM  Christian Peham DME  PhD  Barbara Bockstahler DVM 《Veterinary surgery : VS》2015,44(5):588-595

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Effects of the needle bladder rust (Chrysomyxa rhododendri) on Norway spruce: implications for subalpine forests     

Andrea Ganthaler  Helmut Bauer  Andreas Gruber  Michaela Mayr  Walter Oberhuber  Stefan Mayr 《European Journal of Forest Research》2014,133(2):201-211

Norway spruce trees in the subalpine forests of the European Alps are frequently attacked by the needle rust Chrysomyxa rhododendri. The obligate parasite undergoes a complex life cycle with a host shift between rhododendrons (Rhododendron sp.) and Norway spruce [Picea abies (L.) Karsten] and causes a yellowing and defoliation of the current-year needles in summer. Infected trees show several anatomical, morphological and physiological modifications, including a decrease in pigment content and net photosynthesis of infected needles, lower biomass production and reduced radial and height growth. The consequences are diminished timber yield and cripple growth. Because of repeated heavy infections in recent years, forest managers report increasing difficulties in both natural regeneration and afforestation at high elevation sites, where rhododendrons occur. This review gives a summary of the present knowledge about the effects of C. rhododendri infections on Norway spruce, including so far unpublished findings and with particular attention to the phenomena of resistant trees. Implications for subalpine forests and counter strategies are discussed.  相似文献   

Uniaxial compression of rotationally symmetric Norway spruce samples: surface deformation and size effect     

Michaela Zauner  Peter Niemz 《Wood Science and Technology》2014,48(5):1019-1032

The influence of size on strength is well known for various materials and testing methods, but not enough data and knowledge of the effect on wood under compressive strength can be found. Therefore, the deformation and compressive strength of hyperboloid Norway spruce samples were tested for different dimensions. To determine the influence of size on the strength, three different approaches were used: “weakest link theory”, “size effect law” and “multifractal scaling law”. Of the three scaling theories, the “size effect law” and the “weakest link theory” predicted the effect well. Additionally, to determine the surface deformation of various samples, DIC3D was used on the largest sample geometry. The experiments show the existence of a possible size effect during compression, while digital image correlation illustrates the expected differences in deformation due to the shape and dependence of the strain distribution on the structure of wood. Additional experiments are proposed to further verify the observed effects and expand the knowledge of the size effect.  相似文献   

Establishment of proliferative cell nuclear antigen gene as an internal reference gene for polymerase chain reaction of a wide range of archival and fresh mammalian tissues.     

Irene Schiller  Zen Huat Lu  Lloyd Vaughan  Roseline Weilenmann  Stephane Koundrioukoff  Andreas Pospischil 《Journal of veterinary diagnostic investigation》2003,15(6):585-588

Polymerase chain reaction (PCR) from paraffin-embedded tissues provides a powerful tool to amplify DNA from a variety of recent and archival material. Because DNA from paraffin-embedded samples is more degraded than from fresh material, the amplification of reference genes is essential to exclude false-negative results. This study describes the use of the proliferative cell nuclear antigen (PCNA) gene as a reference gene in a range of animal species and in humans. The PCNA-PCR to amplify a fragment extending from exon 5 through exon 6 and including the intervening intron 6 gave a reproducible pattern, with a 280-base pair (bp) band from canine, equine, bovine, ovine, and caprine samples showing high sequence homology. Porcine, guinea pig, tiger, and lion samples, however, gave an additional fragment of approximately 197 bp. The whole intron 6 from these fragments is missing, possibly representing a pseudogene. In feline samples only the 197-bp fragment could be detected. This study shows that the PCNA gene is highly conserved across a broad range of animal species and is well suited as an internal control for PCR analysis in veterinary medicine.  相似文献   

Stem cell depletion through epidermal deletion of Rac1     

Benitah SA  Frye M  Glogauer M  Watt FM 《Science (New York, N.Y.)》2005,309(5736):933-935

Mammalian epidermis is maintained by self-renewal of stem cells, but the underlying mechanisms are unknown. Deletion of Rac1, a Rho guanosine triphosphatase, in adult mouse epidermis stimulated stem cells to divide and undergo terminal differentiation, leading to failure to maintain the interfollicular epidermis, hair follicles, and sebaceous glands. Rac1 exerts its effects in the epidermis by negatively regulating c-Myc through p21-activated kinase 2 (PAK2) phosphorylation. We conclude that a pleiotropic regulator of cell adhesion and the cytoskeleton plays a critical role in controlling exit from the stem cell niche and propose that Rac and Myc represent a global stem cell regulatory axis.  相似文献