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The ethyl acetate, acetone and methanol extracts of Wrightia tinctoria bark showed antinociceptive activity on acetic acid-induced writhing test in mice, their effects being comparable to that of acetylsalicylic acid. 相似文献
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The present study was aimed to investigate the possible interaction of the standardized extract of Acorus calamus (AC) with Cytochrome P450 enzyme, quantitative determination of the α-asarone in the AC rhizome was performed by RP-HPLC method. In vitro interaction of the plant extract was evaluated by CYP450-carbon monoxide complex (CYP450-CO) assay. Effect on individual isoforms such as CYP3A4 and CYP2D6 isozymes were analyzed through fluorescence product formation and respective IC50 values were determined. CYP450-CO assay showed moderate interaction potential. Extract showed higher IC50 values (46.84 ± 1.83-32.99 ± 2.21 μg/ml) comparing to the standard inhibitors and lower IC50 value than α-asarone (65.16 ± 2.37-42.15 ± 2.45 μg/ml). 相似文献
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Kadarkarai Murugan Kandasamy Kalimuthu Palanisamy Mahesh Kumar Jiang-Shiou Hwang Marcello Nicoletti 《Phytoparasitica》2013,41(3):307-316
The efficacy of copepod Mesocyclops aspericornis (Daday) combined with the larvicide Bacillus sphaericus (Bs) and a plant extract of Plectranthus amboinicus leaf abstract (PALE), used jointly and singly, was studied against Aedes aegypti in the laboratory. P. amboinicus leaf extract of 20, 40, 60, 80 and 100 ppm caused significant mortality against Ae. aegypti larvae. The LC50 and LC90 values for I to IV instars larvae and pupae were 26.12, 35.36, 45.76, 52.32 and 63.82 ppm, respectively. The LC90 values for I to IV instars larvae and pupae were 82.53, 92.65, 108.06, 119.47 and 131.71 ppm, respectively. Under laboratory conditions, copepods treatment produced 7.9% predatory efficiency against 1st instar larvae of Ae. aegypti, at a copepod:larvae ratio of 1:10. When copepod treatment was combined with PALE this was increased to 8.7. The treatment of copepods combined with Bs and PALE yielded a better and more sustainable result (9.6%) than the agents used individually. This predation efficiency may be caused by detrimental effects of the P. amboinicus active principle compound (carvacrol) on the mosquito larvae. Our results suggest that the combined application of microbial insecticide (Bs), copepods and P. amboinicus leaf extract may be used to control Aedes populations. 相似文献
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Amarchand Chordia Murugan Jibu Thomas Raj Kumar Rajagopal AbulKalamAzad Mandal 《Journal of Crop Science and Biotechnology》2012,15(1):53-57
Effects of exogenous application of ascorbic acid on physiological and metabolic changes in tea were investigated in the present
study. The highest improvement in yield was evident in response to regular application (a day after every harvest) of ascorbic
acid at 600 ppm followed by 400 ppm. Foliar application of ascorbic acid (600 ppm) at regular intervals enhanced chlorophyll
a and b contents besides a significant increase in total polyphenols and catechins when compared to the untreated control. Exogenous
application of ascorbic acid at alternate harvesting rounds increased the activity of polyphenol oxidase whereas ascorbate
peroxidase remained unchanged. An increase in phenylalanine ammonia lyase activity was noticed with foliar application of
ascorbic acid irrespective of its concentrations. Theaflavins and thearubigins of made tea showed an increase when ascorbic
acid was applied with 400 and 600 ppm at alternate intervals. The scores of brewed tea liquor characteristics, viz. infusion,
color, strength, and briskness were higher even at the lower concentration of ascorbic acid treatment. Results suggest that
foliar application of ascorbic acid (400 ppm) proved to be a useful measure to improve the yield, physiological attributes,
and antioxidant properties of tea. 相似文献
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André Sradnick Mariko Ingold Johanna Marold Rajasekaran Murugan Andreas Buerkert Rainer Georg Joergensen 《Biology and Fertility of Soils》2014,50(1):95-103
Effects of goat manure application combined with charcoal and tannins, added as feed additives or mixed directly, on microbial biomass, microbial residues and soil organic matter were tested in a 2-year field trial on a sandy soil under Omani irrigated subtropical conditions. Soil microbial biomass C revealed the fastest response to manure application, followed by microbial residue C, estimated on the basis of fungal glucosamine and bacterial muramic acid, and finally soil organic C (SOC), showing the slowest, but still significant response. At the end of the trial, microbial biomass C reached 220 μg g?1 soil, i.e. contents similar to sandy soils in temperate humid climate, and showed a relatively high contribution of saprotrophic fungi, as indicated by an average ergosterol to microbial biomass C ratio of 0.35 % in the manure treatments. The mean fungal C to bacterial C ratio was 0.55, indicating bacterial dominance of microbial residues. This fraction contributed relatively low concentrations of between 20 and 35 % to SOC. Charcoal added to manure increased the SOC content and the soil C/N ratio, but did not affect any of the soil microbial properties analysed. Tannins added to manure reduce the 0.5 M K2SO4-extractable N to N total ratio compared to manure control. These effects occurred regardless of whether charcoal or tannins were supplied as feed additive or directly mixed to the manure. 相似文献
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P. Arumugam D. Inbakandan M. S. Ramasamy M. Murugan 《Journal Of Applied Aquaculture》2013,25(3):265-270
Abstract Liposomes were prepared in the laboratory with lipids obtained from chicken egg yolk to encapsulate Spirulina powder. Artemia napulii were hatched and fed with lipid-encapsulated Spirulina or Spirulina powder. After 20 days of rearing, the experimental A. salina were harvested and measured for total body length and total content of protein and carbohydrates. Total body length was 45% higher, protein content was 49% higher, and carbohydrate was 35% higher in Artemia fed with liposomes as compared with those fed only Spirulina powder. 相似文献
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Subramani Paranthaman Balasubramani Ramar Murugan Kaliamoorthy Ravikumar Padma Venkatasubramanian 《Fitoterapia》2010
Tribulus terrestris L. (Zygophyllaceae) is one of the highly traded raw drugs and also used as a stimulative food additive in Europe and USA. While, Ayurvedic Pharmacopoeia of India recognizes T. terrestris as Goksura, Tribulus lanuginosus and T. subramanyamii are also traded by the same name raising issues of quality control. The nuclear ribosomal RNA genes and ITS (internal transcribed spacer) sequence were used to develop species-specific DNA markers. The species-specific markers efficiently amplified 295 bp for T. terrestris (TT1F and TT1R), 300 bp for T. lanuginosus (TL1F and TL1R) and 214 bp for T. subramanyamii (TS1F and TS1R). These DNA markers can be used to distinguish T. terrestris from its adulterants. 相似文献