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It is well documented that synthetic chlorinated hydrocarbon residues are widespread throughout the world ecosystem. Recently serious contamination of the Kupa River in Slovenia resulting from improper disposal of the waste disharged by an electro-capacitor manufacturing plant was observed. The migration of the PCBs from the waste tip into the karst ground water and source water has been established. PCBs have been also introduced into the small Lahinja River a tributary of the Kupa. Consequently, these pollutants have been detected in the Kupa river. An investigation of the levels of chlorinated hydrocarbons in tap water, water and fish samples collected from 1985 to 1988 from the Kupa River in the region of Petrinja and Sisak was performed. This region is about 200 km downstream of the primary contamined area. Concentrations of chlorinated insecticides and polychlorinated biphenyls in tap water ranged from <0.2 to 5.0 ng dm?3 for PCBs such as Aroclor 1254 and from <0.4 to 10.4 ng dm?3 for PCBs such as Pyralene 1500. In the Kupa River, water samples were found with PCBs such as Aroclor 1254 from <1.5 to 5.0 and from <2.6 to 104 ng dm?3 for PCBs such as Pyralene 1500. The level of the investigated chlorinated insecticides were under the sensitivity limits of 0.05 for dieldrin and 0.1 ng dm?3 for DDTs. Concentrations of chlorinated insecticides and polychlorinated biphenyls in the fish samples were several orders of magnitude higher in comparison with the water samples and ranged from the sensitivity limit for dieldrin (<0.0001) to 0.0034 mg kg?1; p,p'DDT from 0.0003 to 0.0076 mg kg?1; p,p'DDE from 0.0004 to 0.1752 mg kg?1; p,p'DDD from 0.0001 to 0.0201 mg kg?1 wet weight. Concentrations of PCBs were significantly higher and ranged from 0.015 to 2.742 mg kg?1 wet weight for Pyralene 1500 and from 0.090 to 1.590 mg kg?1 for Aroclor 1254 +Aroclor 1260. 相似文献
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Peres R. Badial Jos P. Oliveira Filho Paulo Henrique J. Cunha Didier Q. Cagnini Joo P. Araújo Jr Nena J. Winand Alexandre S. Borges 《Research in veterinary science》2011,90(3):443-450
Hepcidin is part of the innate immune system, and it plays a central role in the regulation of iron homeostasis. This peptide has been previously characterized in man, non-human primates, rat, mouse, dog, swine, cattle, horse, fishes, reptiles and birds but until now not in sheep. The aim of this study was to sequence, characterize and perform hepcidin expression analysis in different tissues collected from healthy sheep. The resulting open reading frame consisted of 249 bp predicted to encode an 82 aa peptide with a putative 23 aa signal peptide, a 34 aa pro-region and the 25 aa mature hepcidin. The deduced sequence of the sheep hepcidin precursor was most homologous to Bos taurus and Bubalus bubalis. Hepcidin was predominantly expressed in liver, although high expression was present in abomasum and lower level expression occurred in other tissues. These findings extend our comparative knowledge showing the relationship of sheep hepcidin to other mammalian hepcidins and will be helpful for additional studies on iron metabolism and inflammatory processes in sheep. 相似文献
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Peres R. Badial José P. Oliveira-Filho Nena J. Winand Alexandre S. Borges 《Veterinary journal (London, England : 1997)》2014,199(2):306-307
Hereditary equine regional dermal asthenia (HERDA) is a genetic disorder that occurs in the American Quarter horse (AQH) and is caused by a c.115G>A missense mutation in the peptidylprolyl isomerase B (PPIB) gene. Using a quantitative real-time PCR high resolution melting analysis genotyping assay for the PPIB mutation, the estimated HERDA allele and carrier frequencies in a sample of Brazilian AQHs were 2.9% and 5.8%, respectively. 相似文献
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