Carriage rate and antibiotic susceptibility of coagulase‐positive staphylococci isolated from healthy dogs in Victoria,Australia          下载免费PDF全文

DC Bean  SM Wigmore 《Australian veterinary journal》2016,94(12):456-460

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Transdermal absorption of a liposome-encapsulated formulation of lidocaine following topical administration in cats     

Fransson BA  Peck KE  Smith JK  Anthony JA  Mealey KL 《American journal of veterinary research》2002,63(9):1309-1312

OBJECTIVE: To determine plasma disposition after dermal application of a liposome-encapsulated formulation of lidocaine in cats. ANIMALS: 6 healthy adult cats with a mean (+/- SD) body weight of 4.1 +/- 0.44 kg. PROCEDURE: CBC determination and biochemical analysis of blood samples were performed for all cats. Cats were anesthetized by use of isoflurane, and catheters were placed IV in a central vein. The next day, blood samples were obtained from the catheters before and 1, 2, 3, 4, 6, 8, 10, 12, and 24 hours after applying a 4% liposome-encapsulated lidocaine cream (15 mg/kg) to a clipped area over the cephalic vein. Plasma concentrations of lidocaine were analyzed with a high-performance liquid chromatography assay. Results-Two cats had minimal transdermal absorption of lidocaine, with lidocaine concentrations below the sensitivity of the assay at all but 1 or 2 time points. In the other 4 cats, the median maximum plasma concentration was 149.5 ng/ml, the median time to maximum plasma concentration was 2 hours, and the median area under the concentration versus time curve from zero to infinity was 1014.5 ng.h/ml. CONCLUSIONS AND CLINICAL RELEVANCE: Maximum plasma concentrations of lidocaine remained substantially below toxic plasma concentrations for cats. On the basis of these data, topical administration of a liposome-encapsulated lidocaine formulation at a dose of 15 mg/kg appears to be safe for use in healthy adult cats.  相似文献   

Not classical homeopathy          下载免费PDF全文

Drosdovech M  Neumann S  Evans D  Blake S  Peck LS  Yearout DR  Ulbrich B  Facinelli J  Delgado R  Hoberg L  Harman J  Sthamann M  Lindsay M  Kwong H  Lampru A  Lamb J  Stagmeier K  Doyle JL  Elliot J  Siemon L 《The Canadian veterinary journal. La revue veterinaire canadienne》2002,43(12):908-909

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Clarifying convention session on alternative therapies     

Peck LS 《Journal of the American Veterinary Medical Association》2000,217(10):1458

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Spontaneous bilateral coxofemoral luxation in four dogs     

Trostel CD  Peck JN  deHaan JJ 《Journal of the American Animal Hospital Association》2000,36(3):268-276

Spontaneous bilateral coxofemoral luxations and their clinical managements are described in four dogs. Luxations in each case occurred while the patient was in a controlled environment with no possibility of trauma. While all cases had bilateral luxations, the luxations occurred in a staged fashion in two of the four cases. Treatment varied with each case, but included closed reduction, triple pelvic osteotomy, prosthetic capsulorrhaphy, toggle pin, ischioilial pinning, total hip replacement, and femoral head and neck ostectomy. Other than femoral head and neck ostectomy, results were uniformly poor, with reluxation being the most common complication. Evidence of pre-existing degenerative changes was minimal, particularly considering the ages of the patients (range, three to 12 yrs). Histopathological evaluation of joint capsules, round ligaments, and femoral heads are warranted in future cases.  相似文献   

Otto Martin Radostits 1934 – 2006     

DC Blood  CC Gay  KW Hinchcliff  PD Constable 《Australian veterinary journal》2007,85(6):231-231

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Snake bites recorded by veterinary practices in Australia     

PJ MIRTSCHIN  P. MASCI  DC PATON  T. KUCHEL 《Australian veterinary journal》1998,76(3):195-198

Objective To determine the extent of the snake bite problem in domestic animals, its regional significance and the effects of antivenom treatment.
Design A questionnaire was designed seeking information on the number and type of domestic animals referred, whether treated or untreated, type of snakes and management of the bite.
Procedure The survey form was sent to 10% of veterinary surgeons, selected at random throughout Australia.
Results The response of 106 veterinary surgeons revealed that snake bite in domestic animals is frequent, with an estimated 6200 cases reported annually. Bites were more prominent in rural (78%) than urban areas (22%) with brown, tiger and black snakes accounting for 76%, 13% and 6% of cases, respectively. Cats and dogs were the most frequently reported victims. Ninety-one percent of cats and 75% of dogs survived following the administration of antivenom whereas 66% of cats and 31% of dogs survived without antivenom. Overall, in 33% of cases antivenom was not used, and venom detection kits were used in only 1% of cases. A number of drugs were used in various combinations with or without antivenom and intravenous fluids in the treatment of animals with snake bite, but their role in reducing the severity of envenomations was not assessed.
Clinical implications Antivenom significantly improves the chances of survival of domestic animals bitten by snakes.  相似文献   

Impact of foot-and-mouth disease on mastitis and culling on a large-scale dairy farm in Kenya     

Nicholas A Lyons  Neal Alexander  Katharina DC St?rk  Thomas D Dulu  Jonathan Rushton  Paul EM Fine 《Veterinary research》2015,46(1)

Foot and mouth disease (FMD) is a highly transmissible viral infection of cloven hooved animals associated with severe economic losses when introduced into FMD-free countries. Information on the impact of the disease in FMDV-endemic countries is poorly characterised yet essential for the prioritisation of scarce resources for disease control programmes. A FMD (virus serotype SAT2) outbreak on a large-scale dairy farm in Nakuru County, Kenya provided an opportunity to evaluate the impact of FMD on clinical mastitis and culling rate. A cohort approach followed animals over a 12-month period after the commencement of the outbreak. For culling, all animals were included; for mastitis, those over 18 months of age. FMD was recorded in 400/644 cattle over a 29-day period. During the follow-up period 76 animals were culled or died whilst in the over 18 month old cohort 63 developed clinical mastitis. Hazard ratios (HR) were generated using Cox regression accounting for non-proportional hazards by inclusion of time-varying effects. Univariable analysis showed FMD cases were culled sooner but there was no effect on clinical mastitis. After adjusting for possible confounders and inclusion of time-varying effects there was weak evidence to support an effect of FMD on culling (HR = 1.7, 95% confidence intervals [CI] 0.88-3.1, P = 0.12). For mastitis, there was stronger evidence of an increased rate in the first month after the onset of the outbreak (HR = 2.9, 95%CI 0.97-8.9, P = 0.057).

Electronic supplementary material

The online version of this article (doi:10.1186/s13567-015-0173-4) contains supplementary material, which is available to authorized users.  相似文献   

Evaluation of the effect of ketoprofen on experimentally induced ephemeral fever in dairy heifers   总被引：1，自引：0，他引：1  

DC FENWICK  RCW DANIEL 《Australian veterinary journal》1996,74(1):37-41

Objective To evaluate ketoprofen for the therapy of ephemeral fever.
Design A blind controlled clinical trial.
Animals Sixteen cattle (one immature Holstein bull, eight Holstein and seven Jersey heifers).
Procedure Ephemeral fever was induced by the intravenous injection of blood leucocyte layer from a clinical case. Ketoprofen solution or a coded placebo was injected intramuscularly at the rate of 3 mg/kg daily for three days.
Results Ketoprofen reversed locomotor dysfunctions significantly compared with controls, but did not have any effect on rectal temperatures, leucocyte counts, plasma fibrinogen concentrations, ionised Ca-concentrations or the presence of dyspnoea.
Conclusion Ketoprofen is a safe and effective drug for the treatment of locomotor symptoms of milk fever, but has no effect on the duration of clinical respiratory abnormalities.  相似文献   

Receptor-estrogen complex in the nuclear fraction of rat uterine cells during the estrous cycle     

J H Clark  J Anderson  E J Peck 《Science (New York, N.Y.)》1972,176(34):528-530

A quantitative method was used to determine the concentration of receptor-estrogen complex in the nuclear fraction of rat uterine cells throughout the estrous cycle. The concentrations of nuclear receptor-estrogen complex were: metestrus, 0.22; diestrus, 0.75; proestrus, 1.29; and estrus, 0.31 picomoles per milligram of DNA. This cyclic fluctuation in the nuclear complex closely parallels the secretion of ovarian estrogen during the estrous cycle, an indication that the accumulation of receptor-estrogen complex by the nuclear fraction of uterine cells may be of physiological significance, and under the control of endogenous estrogen.  相似文献