THE EFFECT OF A COMBINATION OF MEDETOMIDINE-BUTORPHANOL AND MEDETOMIDINE, BUTORPHANOL, ATROPINE ON GLOMERULAR FILTRATION RATE IN DOGS     

Jennifer B.  Grimm  DVM  MS  Kurt A.  Grimm  DVM  MS  Stephen K.  Kneller  DVM  MS  William J.  Tranquilli  DVM  MS  Sonia S.  Crochik  DVM  MS  Matthew G.  Bischoff  DVM  Jennifer L.  Podolski  DVM 《Veterinary radiology & ultrasound》2001,42(5):458-462

The effects of intramuscularly administered medetomidine and butorphanol (MB), and medetomidine, butorphanol, atropine (MBA) on glomerular filtration rate (GFR) were determined in six dogs as measured by 99m-Tc-labeled diethylenetriaminepentaacetic acid (99mTc-DTPA) nuclear scintigraphy. Direct systolic, diastolic, and mean arterial blood pressures and heart rate were measured at regular time intervals before, during, and after GFR calculations. The mean GFR measurement following MB was significantly greater (4.44 ml/min/kg) than following MBA (3.82 ml/min/kg) or saline treatment (3.41 ml/min/kg). There was no significant difference between the mean GFR measurements following MBA injection and following saline injection. Diastolic and mean arterial pressures following MBA injection were significantly higher than the values recorded after either MB or saline alone. Heart rate following MB administration was significantly lower than that recorded for dogs receiving MBA or saline alone. The results of this study indicate that the administration of medetomidine in combination with butorphanol significantly increases total GFR in healthy dogs, while the administration of the combination of medetomidine, butorphanol, and atropine does not.  相似文献   

The next step — a monthly journal     

William E. Jones DVM  PhD 《Journal of Equine Veterinary Science》1992,12(6):329

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Characterization of ovine strains of Mycobacterium paratuberculosis by restriction endonuclease analysis and DNA hybridization.     

G W De Lisle  D M Collins  H F Huchzermeyer 《The Onderstepoort journal of veterinary research》1992,59(2):163-165

Restriction endonuclease analysis and DNA hybridization revealed five ovine strains of Mycobacterium paratuberculosis from South Africa had identical DNA patterns to an ovine strain from Canada. Genetically this strain type has features in common with the two major groups of M. paratuberculosis.  相似文献   

A quantitative study of Eimeria infections of goats from central Spain.     

C de la Fuente  J M Alunda 《Veterinary parasitology》1992,41(1-2):7-15

A survey on coccidial infections in goats from central Spain was carried out. Fifty-five goat farms from 28 localities belonging to the three bioclimatic subregions of the area were visited. Individual samples (702) were obtained from the rectum of 130 young (under 1 year of age) and adult (572 over 1 year of age) goats. Coproscopical analyses showed a 100% prevalence and a moderate average intensity (7606.48 +/- 17918.78 Eimeria oocysts per gram of faeces), although wide variations were seen among herds and among individuals within each goat flock. Statistical analysis showed a strong age-related reduction in oocysts output in goats up to 4 years of age. The intensity of coccidial infections (young and adult goats, herds) was independent of the prevailing bioclimatic conditions. Heavier infections in young goats were found in bigger herds, whereas adult goats from these same big flocks (over 300 animals) showed the lowest oocyst output. Under our conditions, neither the female restocking rate nor the age structure seemed to play a significant role in the intensity of the Eimeria infections.  相似文献   

Postanesthetic Pulmonary Edema In an Arab Stallion     

Thomas K. Day DVM  MS    Susan Holcombe VMD  William W. Muir II  DVM  PhD 《Journal of Veterinary Emergency and Critical Care》1993,3(2):90-95

A six-year-old arabian stallion was admitted to The Ohio State University Veterinary Hospital for evaluation and repair of a comminuted fracture of the second phalanx. The horse developed impaired arterial oxygenation during surgey and pulmonary edema post-operatively. We postulate that impaired arterial oxygenation resulted from atelectasis of the dependent lung during annesthesia, and the pulmonary edema occurred following re-expansion of the atelectatic of the initiating cause of the edema, removal of excess lung water from the alveoli, and restoration of normal arterial oxygenation. The horse was fully recovered within 12 hours of initiation of clinical signs of respiratory compromise. The horse was fully recovered within 12 hours of initiation of clinical signs of respiratory compromise. This report describes re-expansion pulmonary edema due to reperfusion injury in a horse, treatment of the condition, and a possible explanation of the pathogenesis of this pulmonary pathology.  相似文献   

A Tremor Syndrome With a Central Axonopathy in Scottish Terriers     

Luc Van  Ham  Marc Vandevelde  Miek Desmidt  Mulenda Tshamala  Luc De  Schaepdrijver Daniel Mattheeuws 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1994,8(4):290-292

A central axonopathy in 2 male and 1 female Scottish Terrier puppies from 3 different but related litters is reported. Clinical signs consisting of severe whole-body tremors and ataxia were first detected at the age of 10 to 12 weeks. They worsened with activity and excitement and diminished during rest or sleep. Two dogs also had paraparesis. In 1 dog the neurological deficits progressed over several months. Neuropathological examination revealed widespread axonal changes, vacuolation, and gliosis in the white matter of the central nervous system.  相似文献   

Use of ⁶⁴Copper Measurements to Diagnose Canine Copper Toxicosis     

George J. Brewer MD    William Schall DVM    Robert Dick BS    Vilma Yuzbasiyan-Gurkan PhD    Michael Thomas DVM  George Padgett DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(1):41-43

Inherited canine copper toxicosis is a serious problem in Bedlington terriers and West Highland White terriers, and may also be a problem in other less-studied breeds. Affected dogs become ill at midlife with progressive and ultimately fatal liver disease. Treatments for removal of copper and prevention of copper accumulation are available, but are most effective if begun before the dog becomes ill. Until recently diagnosis has not been available until the dog is 1 year of age, and then only by an invasive liver biopsy with determination of liver copper concentration. The authors studied the use of 64copper for early diagnosis of canine copper toxicosis. Two procedures were evaluated. The first involved measuring the concentration of 64copper in blood 24 hours after oral administration of the radioisotope. At this time, 64copper was associated primarily with ceruloplasmin secreted into the blood by the liver. This procedure is useful in the diagnosis of the human counterpart, Wilson's disease. However, the authors found it to be nondiscriminatory between affected and unaffected dogs. In contrast, the second procedure, which involved measuring 64copper excreted in stool during 48 hours after an intravenous dose of radioisotope, yielded results that differentiated most affected and unaffected dogs.  相似文献   

Comparison of slot blot nucleic acid hybridization, immunofluorescence, and virus isolation techniques to detect bluetongue virus in blood mononuclear cells from cattle with experimentally induced infection.   总被引：1，自引：0，他引：1  

A de la Concha-Bermejillo  C E Schore  C A Dangler  C C de Mattos  C A de Mattos  B I Osburn 《American journal of veterinary research》1992,53(12):2245-2250

A slot blot hybridization technique was applied for detection of bluetongue virus (BTV) in blood mononuclear cells (BMNC) obtained from cattle with experimentally induced infection. This technique lacked sensitivity to detect the viral nucleic acid directly in clinical specimens. When aliquots of mononuclear cells from these cattle were cultivated in vitro for 10 days to amplify virus titer, only 33.3% of the samples collected during viremia gave a positive signal in the slot blot hybridization format. By contrast, results for 34.3% of noncultured and 63.3% of cultured mononuclear cell samples collected during viremia were positive by immunofluorescence. The average number of infected cells, as detected by immunofluorescence in the noncultured mononuclear cell samples, was 1 to 5/300,000, and was usually > 10/300,000 in the cultured cell samples. Virus was isolated from all postinoculation blood samples obtained from 4 heifers that were seronegative at the time of inoculation, but was not isolated from any of the preinoculation samples, or from any of the postinoculation samples obtained from 2 heifers that were seropositive at the time of inoculation. When virus isolation was attempted from separated mononuclear cells in 2 heifers, 43.7% of the noncultured and 87.5% of the cultured samples had positive results.  相似文献   

鼻气管鸟杆菌对鸡的感染及其防制     

程思明  任文雁  Peter De Herdt 《国外畜牧学(猪与禽)》2002,(1):50-52

鼻气管鸟杆菌发现于 1 990年 ,自那时以来已在世界范围内被公认为一种呼吸道病原菌 ,可在肉用鸡引起原发感染或继发感染。对种鸡进行免疫接种是减轻鼻气管鸟杆菌所致经济损失的有效方法。  相似文献   

RADIOGRAPHIC DIAGNOSIS: PERICARDIOPERITONEAL DIAPHRAGMATIC HERNIA AND CHOLELITHIASIS IN A DOG     

Diana S.  Rosenstein  DVM  Ullrich  Reif  DVM  Russ L.  Stickle  DVM  Gary  Watson  DVM  William  Schall  DVM  Pierre  Amsellem  DVM 《Veterinary radiology & ultrasound》2001,42(4):308-310

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