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1.
A number of N2-alkyl and N2-acyl derivatives of guanosine 5'-phosphate (GMP) have been synthesized and tested for their synergistic effect with monosodium L-glutamate (MSG), the prototypical substance imparting umami taste to savory-based foods. Capacities to enhance the taste intensity of MSG (gamma values) were estimated through subjective comparisons of MSG/nucleotide mixtures in water with appropriate solutions of MSG alone. Assuming beta = gamma[nucleotide]/gamma[IMP], beta values of the N2-substituted GMPs were found in the range 1.2-5.7. Such values appear to be related to the chain length of the substituent in the 2-position of the purine nucleus and dependent on the replacement of a CH 2 group with an S atom and/or with an alpha-CO group. These findings indicate that the exocyclic NHR group of the guanine moiety is actively implicated in the synergism between GMP derivatives and MSG. Theoretical calculations suggest that an anti conformation is probably assumed by ribonucleotide molecules interacting with umami receptors.  相似文献   
2.
Veterinary Research Communications - Canine parvovirus type 2 (CPV-2) is one of the most relevant pathogens associated with enteritis in dogs and is frequently reported in association with the...  相似文献   
3.
Two new compounds, 10-O-beta-D-glucopyranosyl aloenin (4) and 8-C-beta-D-glucopyranosyl-7-O-methyl-(R)-aloesol (6), were isolated from a commercial sample of Kenya aloe together with the known products aloenin (2), aloenin 2'-p-coumaroyl ester (3), aloenin aglycone (1), orcinol and acetylorcinol. All structures were determined or confirmed by spectral analyses.  相似文献   
4.
In this work the formation and composition of aggregates between metals and organic material is studied in real fog samples. In a preliminary experiment it has been found that concentrated cloud samples form a yellow-brown precipitate in the presence of Fe(III). Standards of humic acids and fulvic acids co-precipitate with Fe(III), forming similar aggregates i.e. iron-humates (Fe-HA) and iron-fulvates (Fe-FA). By comparing the solubility properties of aggregates by extracting organic carbon (OC) in different pH conditions, it has been observed that fog droplet particulate samples are characterised by solubility properties more similar to those of Fe-HA than Fe-FA. Dilute alkaline solutions can also easily extract organic refractory substances that form aggregates with metals. The recoveries of the total extractable organic matter (accounting for 12% of total insoluble carbon and 15% of particulate mass) are similar to those of humic-like substances (HULIS) from particulate samples. The chromatographic behaviour and functional group characteristics measured in the alkali-extract fraction of precipitated aggregates with iron and in the insoluble particulate of fog samples, are those of humic-like material. Thus, soluble HULIS are able to interact with iron to form particulate, but the composition of a large fraction of insoluble organic carbon is still unknown. These findings have implications on the solubility and surface tension properties of fog droplets and can therefore potentially influence droplet formation, as well as cloud chemical and photochemical processes.  相似文献   
5.
By means of an international project, Argentinian and Italian researchers are carrying out joint research to study biological and ecological aspects of Tuta absoluta biological control. This paper lists indigenous natural enemies reported for T. absoluta, as well as the current results on T. absoluta egg and larval parasitoids in both countries. Parasitoid species that conformed to different guilds are shown to coexist in cropping conditions, and some show positive characteristics as potential biocontrol agents against T. absoluta by means of augmentative releases. Future laboratory and field evaluations of the efficacy of biological control programmes in Argentina and Italy are proposed.  相似文献   
6.
Soil Bulk Density (BD) is an extremely important variable because it is an important site characterization parameter, and it is highly relevant for policy development because it is mandatory for calculating soil nutrient stocks. BD can influence soil chemical properties, land-use planning and agronomic management. The 2018 Land Use and Coverage Area Frame Survey (LUCAS) saw the unprecedented collection of BD core analysis in a subset of the locations in Europe and the United Kingdom where soil physical and chemical properties were analysed in the 2009 and the 2015 sampling campaigns. Here, we integrated the LUCAS 2018 BD sampling campaign with the mass fraction of coarse fragments previously determined in LUCAS 2009–2015 in order to provide a dataset of the volume fraction of coarse fragments and the BD of the fine earth and improve soil organic carbon (SOC) stock estimation accuracy for topsoil. BD data sampled at 0–10 and 10–20 cm were averaged to harmonize the BD with the mass fraction of coarse fragments measured in 2009, 2012 and 2015. Samples were from cropland, grassland and woodland soils, which accounted for 41%, 21% and 30%, respectively, of the total number of selected sites (n = 6059); ‘bareland’, and ‘shrubland’ accounted for 3% of the sites each, whereas ‘artificial land’ accounted for <1%. Only six samples were classified as ‘wetland’. The dataset was produced assuming the mass density of the coarse fraction to be constant across all LUCAS soil samples. We also estimated the SOC stocks associated with LUCAS 2018 BD and SOC content measurements and showed that correcting the BD by the coarse mass fraction instead of the coarse volume fraction generates SOC stock underestimation. We found the highest deviations in woodlands and shrublands. We showed that, when SOC stock is computed with coarse mass fraction, the error compared with the computation by volume may vary depending on the SOC and coarse mass fraction. This may imply a SOC stock underestimation for European soils. This dataset fits into the big framework of LUCAS soil properties monitoring and contributes both to soil awareness and soil research and assessments, which are two important objectives of the Soil Strategy and the European Soil Observatory (EUSO).  相似文献   
7.
Whole plant foods, including fruit, vegetables, and whole grain cereals, protect against chronic human diseases such as heart disease and cancer, with fiber and polyphenols thought to contribute significantly. These bioactive food components interact with the gut microbiota, with gut bacteria modifying polyphenol bioavailability and activity, and with fiber, constituting the main energy source for colonic fermentation. This paper discusses the consequences of increasing the consumption of whole plant foods on the gut microbiota and subsequent implications for human health. In humans, whole grain cereals can modify fecal bacterial profiles, increasing relative numbers of bifidobacteria and lactobacilli. Polyphenol-rich chocolate and certain fruits have also been shown to increase fecal bifidobacteria. The recent FLAVURS study provides novel information on the impact of high fruit and vegetable diets on the gut microbiota. Increasing whole plant food consumption appears to up-regulate beneficial commensal bacteria and may contribute toward the health effects of these foods.  相似文献   
8.
In this work, we documented the influence of earthworm's galleries on their speed of movements during dispersal events in the soil. We quantified, by using X-rays, the dispersal behaviour of earthworms in the soil. The observations were conducted in mesocosms in controlled conditions for 12?h. Our experiments revealed that during a dispersal sequence of a batch of individuals of the species Aporrectodea terrestris (Savigny 1826): (a) individuals used preferentially existing conspecifics' galleries, (b) individual velocity increased after each dispersal event and (c) the lag time before each dispersal event did not seem to be influenced by previous dispersers. Therefore, dispersal seems to be facilitated by conspecifics' activity, which strongly supports the hypothesis of a feedback between ecosystem engineers' activity and their dispersal speed.  相似文献   
9.
Leptin regulates body weight and several physiological processes including reproduction. We evaluated the circulating levels of leptin in pregnant and non-pregnant bitches as well as their correlation with body weight, food intake and number of foetuses. Nineteen healthy German shepherd bitches were used and divided in two groups (pregnant n = 12 and non-pregnant n = 7). Blood samples were collected every 15 days starting from ovulation (Day 0) throughout pregnancy (pregnant group, P) or throughout luteal phase (non-pregnant group, NP) In pregnant bitches, leptin concentrations increased from the day of ovulation (1.32 ± 0.06 ng/ml) up to day 45 (1.51 ± 0.06 ng/ml; p < .01) and returned to baseline values from day 60 post-ovulation. In non-pregnant bitches, leptin concentrations remained constant throughout the whole observation period (estimated marginal mean ± SE=1.33 ± 0.38 ng/ml). Pairwise comparisons showed significant differences between P and NP at day 45 post-ovulation (p < .05). Multivariable models indicated that, controlling for time and litter size, there was a positive relationship between leptin concentration and BW (p < .05) although Pearson coefficients showed that the correlation between BW and leptin was only significant in NP animals at day 45 (r = 0.76, p < .05). The multivariable approach also suggested that, holding BW and time constant, leptin concentrations tend to increase as the number of puppies increased (p = .06). Our study supports indirectly the contribution of the feto-placental unit to the circulating maternal leptin concentration.  相似文献   
10.
Pollen grains collected from trees of Quercus ilex L. belonging to different classes of new type damage were analyzed. Five parameters were taken into account: viability, germinability, tube lengthening, grain volume of the dehydrated state and after rehydration. Damage to mother plants clearly influences the above mentioned parameters, causing a reduction in pollen grain viability, germinability, and in the ability of the grains to rehydrate.  相似文献   
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