Selenium, vitamin E and polyunsaturated fatty acid concentrations in goat kids with and without nutritional myodegeneration     

Rammell CG  Thompson KG  Bentley GR  Gibbons MW 《New Zealand veterinary journal》1989,37(1):4-6

Mean selenium and vitamin E (alpha-tocopherol) concentrations in the liver, myocardium and skeletal muscle of nine goat kids with nutritional myodegeneration (NMD) were significantly lower than those in a group of nine kids dying from other causes. Each of the 18 kids was from a different property in the southern half of the North Island. The polyunsaturated fatty acid composition of the liver, myocardium and skeletal muscle was not significantly different between the two groups, but the overall level of peroxidisable polyunsaturated fatty acids appeared high in both groups. A further 21 kids with confirmed NMD and live 'controls', submitted as routine cases to Palmerston North Animal Health Laboratory, were included with the above 18 kids in a comparison of liver selenium and alpha-tocopherol concentrations. Kids with NMD had liver selenium concentrations ranging from 170-1100 (mean = 380) nmol/kg and alpha-tocopherol from 0.7-11.0 (mean =2.2) micromol/kg. In control kids, the liver selenium concentration ranged from 530-4300 (mean = 1220) nmol/kg and a-tocopherol from 1.7-14.0 (mean = 5.6) pmollkg. Although these ranges overlapped, the results suggest that liver selenium concentrations <500 nmol/kg and alpha-tocopherol concentrations <2.5 micromol/kg should be regarded as deficient. Liver selenium concentrations from 500-1100 nmol/kg and alpha-tocopherol concentrations from 2.5-10 micromol/kg should be considered marginal. Goat kids appear to require more selenium than lambs or calves which may explain the higher prevalence of NMD in kids. In some cases, however, the disease is associated with low alpha-tocopherol suggesting that supplementation with selenium alone may not always be sufficient.  相似文献   

Limited effects of land use on soil dissolved organic matter chemistry as assessed by excitation–emission fluorescence spectroscopy and molecular weight fractionation          下载免费PDF全文

P. Roberts  J. M. Gibbons  P. W. Hill  D. L. Jones  M. Farrell 《Soil Use and Management》2016,32(4):662-665

Dissolved organic matter (DOM) in soil solution represents a complex mixture of organic molecules and plays a central role in carbon and nitrogen cycling in plant–microbial–soil systems. We tested whether excitation–emission matrix (EEM) fluorescence spectroscopy can be used to characterize DOM and support previous findings that the majority of DOM is of high molecular weight (MW). EEM fluorescence spectroscopy was used in conjunction with MW fractionation to characterize DOM in soil solution from a grassland soil land management gradient in North Wales, UK. Data analysis suggested that three distinct fluorescence components could be separated and identified from the EEM data. These components were identified as being of humic‐like or fulvic‐like origin. Contrary to expectations, the majority of the fluorescence signal occurred in the small MW (<1 kDa) fraction, although differences between soils from the differently managed grasslands were more apparent in larger MW fractions. We conclude that following further characterization of the chemical composition of the fluorophores, EEM has potential as a sensitive technique for characterizing the small MW phenolic fraction of DOM in soils.  相似文献   

In this issue – December 2015          下载免费PDF全文

AE Jackson 《Australian veterinary journal》2015,93(12):431-432

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Pharmacokinetics of single‐dose oral ponazuril in weanling goats          下载免费PDF全文

D. Love  P. Gibbons  V. Fajt  M. Jones 《Journal of veterinary pharmacology and therapeutics》2016,39(3):305-308

Ponazuril (toltrazuril sulfone) is a triazine antiprotozoal agent that targets apicomplexan organisms. Ponazuril may have clinical application in the treatment of clinical coccidiosis due to Eimeria species in goats, along with other protozoal infections. To evaluate the absorption, distribution and elimination characteristics of ponazuril in goats, a sensitive, validated high‐pressure liquid chromatography and mass spectroscopy method for ponazuril in caprine plasma was developed. After a single oral dose of ponazuril at 10 mg/kg, plasma samples from seven weanling goats were collected and assayed. Plasma concentrations of ponazuril in the goats peaked at 36 ± 13 h post drug administration at a concentration of 9 ± 2 μg/mL. Concentrations declined to an average of 4.2 ± 0.8 μg/mL after 168 h with an average elimination half‐life of 129 ± 72 h post drug administration. This study shows that ponazuril is relatively well absorbed after a single oral dose in goats. Efficacy trials are underway to determine clinical efficacy of ponazuril in the treatment of clinical coccidiosis in goats at 10 mg/kg dosage.  相似文献   

In this issue – November 2016          下载免费PDF全文

AE Jackson 《Australian veterinary journal》2016,94(11):395-396

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In this issue – June 2011     

AE Jackson 《Australian veterinary journal》2011,89(6):197-198

Computer model predictions and field observations of anthelmintic resistance in sheep · Dangers of off‐label use of barium selenate · Elbow luxation in dogs and cats · Prognosis of joint infections in adult horses · Omentalisation for mediastinal abscess in a dog · Adenoviruses in lizards  相似文献   

Clinical application of a polymerase chain reaction assay in the diagnosis of pneumonia caused by Rhodococcus equi in a horse     

Vivrette SL  Sellon DC  Gibbons DS 《Journal of the American Veterinary Medical Association》2000,217(9):1348-1350

Diagnosis of pneumonia caused by Rhodococcus equi can be made more rapidly by use of a polymerase chain reaction (PCR) assay than by use of conventional bacteriologic culture techniques. Use of a PCR assay aids in the differentiation between virulent and avirulent strains of R equi, and the assay may be used to identify R equi in feces and soil of breeding farms.  相似文献   

In this issue – September 2009     

AE Jackson 《Australian veterinary journal》2009,87(9):345-346

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Presentation,treatment, and outcome of squamous cell carcinoma in the perineal region of 9 goats     

Philippa M. Gibbons  Lauren Lamb  Joanne Mansell 《The Canadian veterinary journal. La revue veterinaire canadienne》2015,56(10):1043-1047

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An outbreak of primary photosensitisation in lambs secondary to consumption of Biserrula pelecinus (biserrula)          下载免费PDF全文

AE Kessell  GE Ladmore  JC Quinn 《Australian veterinary journal》2015,93(5):174-178

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