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Sinoatrial syncope in Miniature Schnauzers 总被引：2，自引：0，他引：2
R L Hamlin D L Smetzer E M Breznock 《Journal of the American Veterinary Medical Association》1972,161(9):1022-1028
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B Berger P G Whiting E M Breznock R Bruhl-Day P F Moore 《Journal of the American Veterinary Medical Association》1986,188(5):517-521
Five young cats with portosystemic communications, 2 with single intrahepatic and 3 with single extrahepatic portosystemic communications, were managed surgically. One cat with a ductus venosus was treated successfully by surgery. Ptyalism and behavioral changes were similar in all 5 cats. Biochemical abnormalities included low BUN values, increased blood ammonia values, and increased sulfobromophthalein retention. None of the cats had portal hypertension at the time of surgery. Seemingly, single portosystemic shunts should be considered a surgical disease in the cat. 相似文献
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Steven L. Peterson DVM MS Philip D. Koblik DVM MS Pamela G. Whiting DVM Eugene M. Breznock DVM PhD 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1991,5(2):71-74
A chromogenic Limulus amebocyte lysate assay was used to measure portal and peripheral venous endotoxin concentrations in ten medically managed dogs undergoing surgery for correction of a single extrahepatic portosystemic shunt. In all dogs, both peripheral and portal venous blood samples were obtained at the time of surgical manipulation of the anomalous vessel. In six dogs, peripheral venous samples were obtained an average of 8.0 months after surgery. Five physically normal dogs without biochemical or histologic evidence of liver disease served as controls. Data analysis failed to demonstrate significant differences in peripheral and portal venous endotoxin concentrations between the control and study groups. Postoperatively five of six dogs showed a measurable reduction in peripheral venous endotoxin concentration over intraoperatively obtained values, but the differences were not statistically significant (P = 0.06). Based on results of this study it was concluded that systemic endotoxemia was not present in dogs with a single extrahepatic portosystemic shunt that were medically stable prior to surgery. 相似文献
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Philip D. Koblik DVM William J. Hornof DVM MS Eugene M. Breznock DVM PhD 《Veterinary radiology & ultrasound》1983,24(5):232-236
Quantitative hepatic scintigraphy is a valid means for estimating total liver blood flow and relative portal hepatic perfusion. The Hepatic perfusion index (HPI) was determined for a group of 12 dogs with portosystemic shunts prior to and two days after corrective surgery. HPI values for the dogs prior to operation were significantly elevated (p<0.001) as compared with those for a group of normal dogs, indicating reduced effective portal hepatic perfusion in dogs with shunts. Dogs showing a favorable clinical response after surgery had a significant decrease (p<0.02) in HPI values after operation. One dog showing a poor clinical response after operation had an increase in HPI score after operation. Quantitative hepatic scintigraphy is a valuable diagnostic test for screening presumptive cases of portosystemic shunts and monitoring the response to surgical intervention. 相似文献
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Valved apico-aortic conduit for relief of left ventricular hypertension caused by discrete subaortic stenosis in dogs 总被引：1，自引：0，他引：1
E M Breznock P Whiting D Pendray B Thomas D Strack T Bauer P Koblik W Hornof J D Ludders 《Journal of the American Veterinary Medical Association》1983,182(1):51-56
A double-outlet left ventricle (LV), with a valved conduit interposed between the LV apex and the aorta, was created in 7 dogs with subaortic stenosis. Of 8 dogs in which the implantation was attempted, 1 died following thoracotomy but before conduit implantation could be performed, 1 died from hemorrhage 24 hours after surgery, 1 died from septicemia as a sequel to pneumonia 10 days after surgery, 1 died from "shock-lung" 4 days after surgery, and 4 were functionally normal 22, 12, 6, and 2 months after surgery. In the 7 dogs in which the implantation was completed, the mean LV to aorta (LV-Ao) pressure gradient was significantly (P less than 0.01) reduced by the implantation. Diastolic and systolic murmurs were detected over the prosthetic valve area in 3 of the 4 surviving dogs 1 to 4 days postoperatively, but the murmurs gradually decreased in intensity until they disappeared after 1 month. The 4 survivors had no angiographic evidence of prosthetic valve insufficiency at 2 months or at 1 year. In 3 of the survivors, the LV-Ao pressure gradients 2 months postoperatively were 45, 20, and 0 mm of Hg, as compared with 120, 90, and 50 mm of Hg preoperatively. Postoperative pressure measurements were not obtained on 1 surviving dog. 相似文献
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A gallbladder cannula suitable for chronic implantation in the dog is described. The device is simple to operate, inexpensive to construct, durable, and easy to implant. With the cannula in place, measurements of hepatic and biliary drug kinetics, as well as enterohepatic function, in the awake nonstressed animal are possible. Minimal postoperative care is required after implantation of the device. 相似文献
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