排序方式： 共有27条查询结果，搜索用时 15 毫秒
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Dijkman H 《Tijdschrift voor diergeneeskunde》2006,131(14-15):551
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Ingeborg van den Beukel Remco Klaassen Guus B Smit Regina G
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M van Kleef Marga Oortgiesen 《Pest management science》1999,55(10):1031-1033
Species-specific agonist binding regions of nicotinic acetylcholine receptors (nAChR) were examined. Imidacloprid and physostigmine (Phy) selectively activated insect nAChR composed of Drosophila second alpha-like subunit (SAD) and chick β2, in contrast to rat α7 nAChR. The Phy-activated currents were α-bungarotoxin (α-BGT) sensitive, suggesting activation at the agonist binding loop C. Several SAD-α7 chimeras were constructed, by switching agonist binding regions, and expressed in oocytes. Though none of the chimeras was activated by a range of nicotinic agonists, [125I]α-BGT binding revealed homomeric assembly of all chimeric cDNAs. Phy differentially displaced [125I]α-BGT from the nAChR chimeras, suggesting that the β subunit is not involved in Phy binding, and that Phy targets the insect agonist binding loop C. 相似文献
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S. Veraa R. Dijkman W. R. Klein A. J. M. van den Belt 《Equine Veterinary Education》2009,21(6):284-288
Malignant tumours are uncommon in horses, but when they do occur, they are most frequently found in the head. Clinical findings, such as facial swelling and nasal discharge, are frequently encountered but are nonspecific. To highlight the usefulness of a computed tomography (CT) examination in malignancy in the equine head, this Case Report describes the CT features of a leiomyosarcoma, an osteosarcoma and a sarcoma in 3 horses. CT of the equine head was able to provide more information about the extent and severity of lesions than conventional radiography in these cases. 相似文献
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Remco Ursem Yury Tikunov Arnaud Bovy Ralph van Berloo Fred van Eeuwijk 《Euphytica》2008,161(1-2):181-193
Network analysis of correlations between abundances of metabolites across tomato genotypes can help in unraveling the biological
basis of organoleptic variation in tomato. We illustrate how to construct and interpret simple correlations networks using
metabolic data collected on a diverse set of tomato genotypes. Various types of correlations are calculated and displayed
in the form of networks. Interpretations on the basis of network analyses are compared to interpretations following principal
components analysis. 相似文献
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Pearson R.A. Dijkman J.T. Krecek R.C. Wright P. 《Tropical animal health and production》1998,30(1):67-78
Two experiments were designed to compare the energy used in carrying loads by donkeys and ponies. In the first experiment 3 donkeys and 3 ponies were compared on treadmills in the UK. Density of load (lead shot or straw) had no significant effect on the energy cost of carrying loads; however, the energy cost of carrying a load decreased significantly (p<0.001) as the weight of the load increased (in donkeys 6.44, 4.35 and 3.03 J/kg load/m, in ponies 5.82, 3.75 and 3.68 J/kg load/m, for loads of 13, 20 and 27 kg/100 kg liveweight (M) respectively). Differences between species were not significant. In the second experiment energy expenditures were determined in 3 donkeys carrying loads equivalent to 40 kg/100 kg M over gently undulating gravel tracks in Tunisia. Energy costs of carrying the load were 2.34 (SE 0.07) J/kg load/m. The results of both experiments showed that provided the load is balanced, density does not significantly affect the energy cost of carrying; however, as the weight of the load increased then the unit energy cost of carrying it decreased. This suggests that it is more efficient in terms of energy used to carry loads equivalent to 27 to 40 kg/100 kg M than it is to carry lighter loads of less than 20 kg/100 kg M. 相似文献
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